M. Rollone

P458: Safety and tolerability of combined prolonged-release oxycodone and naloxone in the management of chronic pain in the elderly

with an estimated glomular filtration rate (eGFR) of ≤50ml/min and with active renally eliminated medications were selected daily by using the hospital information system (CSC). The selected patients were screened by the pharmacists. When a dose adjustment was required or if a drugs were prescribed that are unwanted in renal failure, the prescribing physician was notified. Results: In 2013 there were 295 notifications for dose adjustments according to the clinical rule in our hospital with 450 beds. More data will be presented in the poster presentation. Conclusions: Implementation of the clinical rule for dose adjustment according to renal function has lead to abundant interventions by prescribing physicians.

Pain treatment in the elderly: A new pharmacological approach

ing Scale) in order to determine fall risk in elderly people. One hundred and fifty subjects with mild fall risk met inclusion criteria (mean age 64,85 ys) were randomized into two groups: 75 for group treated with Human Body Posturizer (HBP) and 75 for placebo group. Results.– HBP group showed a significant difference in Short Physical Performance Battery, Tinetti Scale and Pain Numeric Rating Scale (P<0.05). A significant reduction in fall risk was shown in HBP group. Conclusion.– The use of exoskeleton Human Body Posturizer seems to be a new significant device for prevention of fall in elder patients. Further studies will be performed in order to demonstrate the efficacy of this device on elder patients.