M. T. Carlevato
University of Turin
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by M. T. Carlevato.
Acta Oto-laryngologica | 1995
Mario Bussi; Guido Valente; M. P. Curato; M. T. Carlevato; Giorgio Cortesina
We used histological and histochemical methods to investigate the possible changes with time in skin transposed into the oropharynx and oral cavity of patients whose surgical wounds were reconstructed with the classic pectoralis major flap. We found histological evidence that skin morphology was maintained (keratinization with reduced, but the desquamating layer, hair follicles, sweat and sebaceous glands were identifiable), and noted an intense inflammatory reaction in the dermis. Histochemical studies confirmed the progressive flattening of the basal interdigitations between the epithelium and dermis, and the gradual reconstruction of the basement membrane. Although skin-mucosa continuity developed fairly quickly without scar reactions, the two epithelia maintained their original patterns of keratin production, i.e., their textural peculiarities. We propose an original method for the transposition of muscular flaps implanted with autologous culture of keratinocytes, an approach developed in an attempt to ensure more satisfactory rehabilitation of the removed mucosal structures.
Acta Oto-laryngologica | 1991
Mario Bussi; M. T. Carlevato; Emanuela Galeazzi; B. Morra
The phenotypical and functional aspects of tonsillar (TMNC) and peripheral blood mononuclear cells (PBMNC) obtained from 40 patients who had undergone adeno-tonsillectomy for different tonsillar diseases were investigated. TMNC and PBMC were separately tested at the time of surgery; then a further investigation on the peripheral blood lymphocytes was performed three months after surgery. The most interesting findings are presented and discussed with particular attention to their clinical implications.
Acta Oto-laryngologica | 1995
Giorgio Cortesina; Manuela Sacchi; Mario Bussi; Benedetta Panizzut; S. Ferro; M. T. Carlevato; P. C. Marchisio
Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumours ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.
Acta Oto-laryngologica | 1996
Giorgio Cortesina; Mario Bussi; M. T. Carlevato; S. Ferro; Benedetta Panizzut; Andrea Luigi Cavalot; C. F. Gervasio; P. C. Marchisio
Thirty laryngeal carcinomas were studied immunohistochemically in order to evaluate whether the expression and different distribution of adhesion molecules influence the clinical features and progression of the tumors. On the basis of clinical and pathological variables, two different groups were established: one with good and the other with poor prognosis. The patients were included in one of the two groups on the basis of prognostic factors previously studied by multivariate analysis (the validity of this choice was confirmed by the NED survival curves of the two groups). Different integrins, type I and V laminin and type IV collagen were evaluated by means of monoclonal antibodies in the tumoral specimens and in normal mucosa. Univariate statistical analysis was performed to evaluate differences between the two groups. The degree of expression and pattern of distribution were different in tumor compared with normal mucosa and significant differences were found between the good- and worst-prognosis tumors.
Acta Oto-laryngologica | 1993
Giorgio Cortesina; M. T. Carlevato; Mario Bussi; C. Baldi; Majore L; C. Ruffino
Secretory IgA (SIgA) is the main agent protecting the mucosal districts against both infectious microorganisms and inert foreign macromolecules. A lack of secretory immunity has previously been described in patients with allergic rhinitis, but it is a controversial finding. The discrepant results of SIgA levels found in allergy may partially be due to methodological problems. Sixty patients with previously demonstrated allergic rhinitis, treated or not with specific desensitization therapy and free from clinical manifestation of rhinitis were studied. Normal volunteers and patients with selective 11S IgA deficit, without allergic pathology, were investigated as controls. The titration of SIgA in nasal secretions, performed by an original immunoisoelectro-focusing method, showed significantly decreased values in allergic patients. An evaluation of the IgE level in nasal secretion was performed by ELISA. Low rates of IgE were also found in the intercritic period.
Acta Oto-laryngologica | 1996
Mario Bussi; M. T. Carlevato; Benedetta Panizzut; Paola Omedè; Giorgio Cortesina
Acta Otorhinolaryngologica Italica | 1997
Panizzut B; M. T. Carlevato; Ferro S; Andrea Luigi Cavalot; Gervasio Cf; Ricci E; Trusolino L; Marchisio Pc; Giorgio Cortesina
International Journal of Pediatric Otorhinolaryngology | 1996
Mario Bussi; M. T. Carlevato; Benedetta Panizzut; Lidia Majore; Fulvia Giaretta; Paola Omedè
Acta Otorhinolaryngologica Italica | 1995
Mario Bussi; M. T. Carlevato; Majore L; Battaglio S; Napoli P; Giorgio Cortesina
Acta Otorhinolaryngologica Italica | 1992
M. T. Carlevato; Battaglio S; Emanuela Galeazzi; Mario Bussi