M. Zardini
University of Insubria
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Publication
Featured researches published by M. Zardini.
Journal of Cardiovascular Electrophysiology | 2001
M. Tritto; M. Zardini; Roberto De Ponti; Jorge A. Salerno-Uriarte
Coronary Sinus Atrial Tachycardia. A case of iterative atrial tachycardia leading to dilated cardiomyopathy is reported. During electrophysiologic study, the tachycardia showed a markedly irregular cycle length associated with changes in atrial activation breakthrough as demonstrated by coronary sinus (CS) recordings and frequently degenerated into self‐terminating atrial fibrillation. Left atrial transseptal mapping demonstrated the earliest endocardial atrial activation close to the posterolateral mitral annulus, but this was invariably later than that recorded within the CS, where low‐energy radiofrequency applications eliminated the tachycardia. No acute vessel damage was observed at postablation CS angiography. In accordance with previously published experimental data, we hypothesized that the muscular sleeves surrounding the CS might be involved in the genesis of this tachycardia. During 6‐month follow‐up, the patient remained asymptomatic without tachycardia recurrences and with complete recovery of left ventricular function, confirming the reversible nature of the tachycardia‐induced cardiomyopathy.
American Journal of Cardiology | 2003
M. Tritto; Roberto De Ponti; M. Zardini; G. Spadacini; Jorge A. Salerno-Uriarte
heart. Am Heart J 1963;66:498–508. 5. Ho SY, Sanchez-Quintana D, Cabrera JA, Anderson RH. Anatomy of the left atrium: implications for radiofrequency ablation of atrial fibrillation. J Cardiovasc Electrophysiol 1999;10:1525–1533. 6. Wang K, Ho SY, Gibson DG, Anderson RH. Architecture of atrial musculature in humans. Br Heart J 1995;73:559–565. 7. Ho SY, Sanchez-Quintana D. Structure of the left atrium. Eur Heart J 2000;2(suppl K):4–8. 8. Mansour M, Mandapati R, Berenfeld O, Chen J, Samie FH, Jalife J. Left-toright gradient of atrial frequencies during acute atrial fibrillation in the isolated sheep heart. Circulation 2001;103:2631–2636. 9. Derakhchan K, Li D, Courtemanche M, Smith B, Brouillette J, Page PL, Nattel S. Method for simultaneous epicardial and endocardial mapping of in vivo canine heart: application to atrial conduction properties and arrhythmia mechanisms. J Cardiovasc Electrophysiol 2001;12:548–555. 10. Allessie MA, Lammers WJEP, Bonke FIM, Hollen J. Experimental evaluation of Moe’s multiple wavelet hypothesis of atrial fibrillation. In: Zipes DP. Jalife J, eds. Cardiac Electrophysiology and Arrhythmias. New York: Grune & Stratton, 1985:265–275. 11. Schuessler RB, Boineau JP, Bromberg BI, Hand DE, Yamauchi S, Cox JL. Normal and abnormal activation of the atrium. In: Zipes DP. Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside, 2nd ed. Philadelphia: W. B. Saunders, 1995:543–562. 12. Roithinger FX, Cheng J, SippensGroenewegen A, Lee RJ, Saxon LA, Scheinman MM, Lesh MD. Use of electroanatomic mapping to delineate transseptal atrial conduction in humans. Circulation 1999;100:1791–1797. 13. Schilling RJ, Kadish AH, Peters NS, Goldberger J, Davies W. Endocardial mapping of atrial fibrillation in the human right atrium using a noncontact catheter. Eur Heart J 2000;21:550–564. 14. Durrer D, van Dam RT, Freud GE, Janse MJ, Meijler FL, Arzbaecher RC. Total excitation of the isolated human heart. Circulation 1970;41:899–911.
Archive | 2000
R. De Ponti; Cesare Storti; M. Zardini; M. Tritto; M. Longobardi; P. Fang; J.A. Salerno-Uriarte
The current goal of radiofrequency catheter ablation of supraventricular tachycardias is to cure a large cohort of patients with a primary success rate close to 100% and a complication and recurrence rate close to 0%. In this setting, the ablation of the atrioventricular (A-V) accessory pathway in the triangle of Koch may still represent a grey area, since the strict anatomical relationship between the bypass tract and the A-V node-His bundle may affect the feasibility and safety of the procedure. Consequently, the only rationale for successful ablation with no complication in this area relies on the assumption that the accessory pathway is more sensitive to radiofrequency energy delivery than the normal A-V conduction system [1]. The risk of damaging the normal A-V conduction pathway and of inducing a complete A-V block requiring a permanent pacemaker has been pointed out by both early [2, 3] and recent [4–6] reports, although successful and safe ablation has been described in limited series of cases [7, 8], even with “para-hissian” accessory pathways [1]. Moreover, in the risk/benefit ratio of ablation of by-pass tracts in the Koch’s triangle one must consider not only failure and the risk of permanent complete A-V block, but also the theoretical possibility of creating an incessant reentrant circuit by partially damaging both the accessory pathway and the A-V node conduction.
Archive | 2000
J.A. Salerno-Uriarte; M. Tritto; M. Zardini; R. De Ponti; P. Fang; Cesare Storti; M. Longobardi
Patients submitted to cardiac surgery for correction of congenital or acquired heart diseases may subsequently experience several types of atrial tachyarrhythmias [1–4]. Most of these are macroreentrant atrial tachycardias strictly related to the presence of scars, prosthetic materials, or conduits and have therefore been named “incisional” or “scar-related” atrial tachycardias. Although their electrocardiographic characteristics may resemble those of atrial flutter, slight differences in P wave morphology and tachycardia cycle length are present and should be identified in order to formulate the correct diagnosis. “Incisional” atrial tachycardia may occur at widely variable times after the operation, most frequently in patients submitted to septal atrial defect repair and Fontan or Mustard procedures for tricuspid atresia or great vessel transposition correction, respectively. The true prevalence of these arrhythmias is unknown; small retrospective series reported a prevalence of 32–57% after the Fontan procedure [4, 6, 7] and about 15% after the Mustard operation [3, 8].
Archive | 1998
J.A. Salerno-Uriarte; R. De Ponti; Cesare Storti; M. Zardini; M. Longobardi
In 1997 almost the entire population with arrhythmias related to the presence of an anomalous AV pathway (AP) is treated successfully by radiofrequency catheter ablation (RF-CA) without excessive difficulty, but in some cases a very prolonged procedure or a second session or both are required to obtain a successful outcome [1].
Europace | 2002
M. Tritto; R. De Ponti; M. Zardini; G. Spadacini; J.A. Salerno-Uriarte
Europace | 2003
P. Moretti; M. Tritto; R. De Ponti; M. Zardini; G. Spadacini; B. Molinari; T. Forzani; J.A. Salerno-Uriarte
Europace | 2001
R. De Ponti; M. Tritto; M. Zardini; G. Spadacini; M. Lattanzio; B. Molinari; J.A. Salemo
Europace | 2001
M. Zardini; M. Tritto; G. Spadacini; R. De Ponti; J. A. Salerno
Europace | 2001
R. De Ponti; G. Spadacini; M. Tritto; M. Zardini; F. Cadario; P. Albonico; Ja Salerno