M. Zuheir Al-Kawi

Respiratory arrest: a complication of Arnold-Chiari malformation in adults.

We describe the cases of 2 adult patients who developed respiratory arrest and were found to have Arnold-Chiari malformation on magnetic resonance imaging. Following posterior fossa decompression both patients improved, though one of them subsequently died during sleep. Imaging of the craniocervical junction should be part of the workup of patients with unexplained apneic episodes.

Case report: idiopathic giant cell granuloma of the hypophysis: an unusual cause of panhypopituitarism.

A 37-year-old man presented with headache and reduced libido. He suffered from panhypopituitarism, and the walls of the pituitary fossa were noted to be thickened, sclerotic, and irregular. Computed tomography scans showed an intrasellar and suprasellar, patchy enhancing tumor. From a biopsy taken at transsphenoidal surgery, a giant cell granuloma was diagnosed, for which there was no obvious cause. Inflammatory disease within the pituitary fossa should be suspected if a reaction is seen in the surrounding bone.

Neuroimaging Features of Behcet's Disease

Behcets disease is a multi-system disorder of obscure etiology. The nervous system may be involved with grave prognosis. Pathologically, the lesions are caused by a vasculopathy involving the arte...

Personality Disorders: New Symptom-Focused Drug Therapy

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Stroke in the Young: Experience at King Faisal Specialist Hospital

ABSTRACT Over the past 5 years, 67 patients aged 15 to 45 years have been hospitalized at King Faisal Specialist Hospital with acute stroke syndrome. Of these, 35 patients had cerebral hemorrhage a...

Ethics in medical research and publication.

Ann Saudi Med 2006;26(4):257-260 Research in medicine is an activity conducted with the intent to produce new knowledge. Research may be basic or clinical, a retrospective analysis of data or a prospective clinical study. Research fosters new knowledge and improves clinical practice by improving diagnostic and therapeutic strategies. It is the medical activity that aims at the future. If necessity is the mother of invention, planning and hard work are its parents. In medical research, the scientific method is applied to an incredible diversity of issues. Evidence-based medicine requires that the results of research in prospective clinical trials be used as the best basis for management of many disorders. In general, an observation followed by complex well-organized research confirms or refutes a theory. An erroneous impression fostered by sensational popular ideas is that scientific discovery is often made by inspiration or a coup-de-foudre style invention. Curiosity is an important prerequisite for finding solutions and is a requirement in research. Inventions are usually the final assimilation of innumerable facts and impressions by the mind of a clinician or scientist. Clinical problems give the impetus to research projects. Creative thinking, curiosity, and imagination give momentum to research. The scientist takes up from the manifold observations of his predecessors when carrying out a literature review. Reproduction of research may confirm a scientific observation, while innovation generates new knowledge. New discoveries may originate by serendipity. It is important to appreciate a clue, interpret it and later exploit it. Sir Alexander Fleming in 1928 at St. Mary’s Hospital in London noticed that one culture plate got contaminated with a fungus and the colonies of Staphylococcus around the fungus died out. Following the lead of that significant observation, Fleming went on to discover penicillin, the first and most important antibiotic. This ultimately earned him the Nobel Prize. One important aspect of our profession is its adherence to a code of ethics. Since its earliest recorded history, medical professionals have set specific standards of conduct to guide the behavior of members of the profession. The roots of medical ethics are in the moral and religious principles of the society. Conformity to these standards led to the higher status of the physician in society and safeguarded the welfare of patients. Research has to be based on ethics and mutual trust between the investigator and the research participant. The declaration of Helsinki required that clinical trials should be performed only on volunteers. Innovative therapeutic approaches should always be in the patient’s best interest and risks to patients are minimized. The risk/benefit ratio should be low to justify the research effort. Following Institutional Review Board (IRB) approval, research participants must be informed about the nature of the research. Consent is obtained and alternate therapeutic modalities should be explained and offered to the patient. Ethical guidelines for public announcement of research may not be very clear to scientists. In the era of multimedia, rapid communication Ethics in Medical Research and Publication

Picture Tests and Short Cases for the MRCP

No wonder you activities are, reading will be always needed. It is not only to fulfil the duties that you need to finish in deadline time. Reading will encourage your mind and thoughts. Of course, reading will greatly develop your experiences about everything. Reading picture tests and short cases for the mrcp is also a way as one of the collective books that gives many advantages. The advantages are not only for you, but for the other peoples with those meaningful benefits.

A 900-Year-Old Document Records the Occurrence of Urinary Bilharziasis in Saudi Arabia

ABSTRACT Wadi Al-Aghigh passes into a pond located in a cleft between two mountains. The wadi digs through the narrow passage in the mountain, which is named Suqf. The water flows into a pond calle...

Serum 1,25-Dihydroxycholecalciferol and 25-Hydroxycholecalciferol in Epileptic Patients Taking Anticonvulsants

ABSTRACT Serum 25-hydroxycholecalciferol [25(OH)D] and 1,25-dihydroxycholecalciferol [1,25(OH)2D] were measured in eight normal Saudi Arabian subjects and 13 patients taking anticonvulsants. There ...

Reversible Brain Shrinkage Documented by Computerized Tomography

ABSTRACT The term “cerebral atrophy” is not suitable for describing brain shrinkage demonstrated by CT scanning, because atrophy implies cellular loss and irreversibility. The authors present four ...