Maciej Stodulski
Polish Academy of Sciences
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Publication
Featured researches published by Maciej Stodulski.
Angewandte Chemie | 2009
Joanna Paradowska; Maciej Stodulski; Jacek Mlynarski
Asymmetric organometallic and organocatalytic processes in aqueous systems are currently of great interest. A few years ago, only a few practitioners studied the subject; now organic reactions in water have become one of the most exciting research areas. The quest to identify water-compatible catalysts has evoked an intense search for new possibilities. Following natures lead, the application of amino acids as sources of chiral information seems particularly promising for aqueous systems. Herein we provide an overview of very recent advances in the area of asymmetric catalysis in water with amino acids and their derivatives as effective catalysts or essential components of catalysts.
Journal of Organic Chemistry | 2011
Michał Michalak; Maciej Stodulski; Sebastian Stecko; Adam Mames; Irma Panfil; Magdalena Soluch; Bartłomiej Furman; Marek Chmielewski
A formal synthesis of a powerful cholesterol inhibitor, ezetymibe 1, is described. The crucial step of the synthesis is based on Cu(I)-mediated Kinugasa cycloaddition/rearrangement cascade reaction between terminal acetylene derived from acetonide of L-glyceraldehyde and suitable C,N-diarylnitrone. The adduct with (3R,4S) configuration at the azetidinone ring, obtained with high stereoselectivity, was subsequently subjected to deprotection of the diol side chain followed by glycolic cleavage and base-induced isomerization at the C3 carbon atom to afford the (3S,4S) aldehyde, which has been already transformed into ezetimibe by the Schering-Plough group.
Advanced Synthesis & Catalysis | 2007
Joanna Paradowska; Maciej Stodulski; Jacek Mlynarski
Angewandte Chemie | 2009
Joanna Paradowska; Maciej Stodulski; Jacek Mlynarski
Chemistry: A European Journal | 2006
Jacek Mlynarski; Bartosz Rakiel; Maciej Stodulski; Agata Suszczyńska; Jadwiga Frelek
European Journal of Organic Chemistry | 2008
Maciej Stodulski; Jaroslaw Jazwinski; Jacek Mlynarski
Tetrahedron | 2012
Michał Michalak; Maciej Stodulski; Sebastian Stecko; Magdalena Woźnica; Olga Staszewska-Krajewska; Przemysław Kalicki; Bartłomiej Furman; Jadwiga Frelek; Marek Chmielewski
Tetrahedron-asymmetry | 2008
Maciej Stodulski; Jacek Mlynarski
Tetrahedron-asymmetry | 2011
Maciej Stodulski; Agnieszka Mamińska; Jacek Mlynarski
Tetrahedron Letters | 2016
Filip Stanek; Maciej Stodulski