Majeti Satyanarayana

PRELIMINARY PHYT OCHEMICAL AND ANTHELMINTIC SCREENING OF LEAVES, BARK , ROOTS OF PLANT T ABERNAEMONTANA CORONARIA

Tabernaemontana coronaria is a potent ial non cultivated medicinal plant widely distributed in waste lands and open forests in India. The alcoholic, ethereal and chloroform extracts were obtained from the plant Tabernaemontana coronaria by soxhlet extraction or co ntinuous hot percolation method and the extracts were evaluated for their anthelmintic activi ty , against locally available earth worms ( Pheretima posthuma ). Three concentrations (10, 30, 60 mg/ml) were prepared from each extract and were used for the study over earth worms. The study inv olves the determination of time of paralysis and time for dea th of the earth worms tested. The results obtained from the study revealed that all the extracts of Tabernaemontana coronaria possess significant anthelmintic effect at highest concentration (60 mg/ml). A solution of Albendazole was prepared in same concen tration as that of extract and was used as standard. A 5 % tween - 80 suspension prepared using normal saline solution was used as control