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Dive into the research topics where Makbule Ergin is active.

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Featured researches published by Makbule Ergin.


World Journal of Surgery | 2007

Strength of esophageal closure techniques with and without tissue reinforcement.

Ali Yeginsu; Makbule Ergin; Unal Erkorkmaz

ObjectivesThe purpose of this study was to investigate the effects of esophagotomy closure techniques on the esophageal bursting pressure.Materials and methodsAltogether, 122 freshly dead sheep esophagi received from the local slaughterhouse were prepared for manual closure. After esophagotomy, the specimens were divided into four groups. An interrupted mucosal suture pattern (n = 30), an interrupted mucosal-submucosal suture pattern (n = 30), an interrupted mucosal-submucosal + over-over continuous muscular suture pattern (n = 32), and an interrupted mucosal-submucosal + reinforcement with a diaphragmatic part with full-thickness interrupted U suture pattern (n = 30) were used for esophagotomy closure; 4-0 silk was used in all specimens. Bursting pressures were measured with a sphygmomanometer.ResultsWe found a statistically significant difference among the bursting pressures of all groups (p < 0.001). The bursting pressure values gradually increased from group 1 to group 4 (47.6 ± 22.7, 86.2 ± 49.5, 185.4 ± 53.5, and 226.8 ± 62.4 mmHg, respectively). Reinforcing the esophageal suture line with tissue significantly increased the bursting pressure compared to the other groups.ConclusionsEach layer of the esophagus significantly contributes to strengthening esophageal wall tension with primary esophageal closure, and reinforcement of the esophageal suture with tissue provides an additional significant increase in the bursting pressure of the esophagus.


Journal of Clinical and Analytical Medicine | 2011

Invasive Approaches to the Diagnosis of Pleural Effusion

Makbule Ergin; Kürşat Gürlek; Ali Yeginsu; İsmail Ergin

This article reviews the surgical and other invasive procedures in the management of pleural effusions. Pleural effusion is frequent in clinical practice. Pleural procedures vary from aspiration to more challenging procedures such as thoracoscopy. However it is difficult to make diagnosis by thoracentesis or closed pleural biopsy. Thoracoscopy is gold standart in the investigation and management of pleural disease. Pleural biopsy by thoracoscopy should be actively carried out in patients with pleurisy, because the technique has a high diagnostic rate and can be easily and safely performed. Flexible or rigid thoracoscope, bronchoscope, endoscope and mediastinoscope can be used for operation.


Akdeniz Medical Journal | 2017

During Cardiopulmonary Bypass Release of Mediators and Their Effect on Pulmonary Function

Seçil Sari; Hakan Keskin; Makbule Ergin; Saadet Gümüşlü; Mehmet Ali Şahin; Gizem Esra Genç; Cemal Kemaloğlu; Abdullah Erdoğan

Objective: The heart-lung machine, while playing an extremely important role in the development of cardiac surgery in particular restricts the use of negative effects on the lungs. The resulting postperfusion syndrome or inflammatory response of the body requires a long period of intensive care. In some cases, this may even lead to multiple organ failure or even death. This inflammatory response causes the investigation and to manifest coronary artery bypass grafting (CABG) is one of the most important points made in the case. Material and Methods: In the Cardiovascular Surgery Clinic, cardiopulmonary bypass (CPB) is applied to a control group of 25 patients CABG, coronary artery bypass surgery without CPB implementation of the 10 patients were enrolled into the study. Patients, plasma vascular endothelial growth factor (VEGF) and elastase levels were measured. Pulmonary function test with FEV1, FVC 1Celal Bayar Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Manisa, Türkiye 2Akdeniz Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, Antalya, Türkiye 3Akdeniz Üniversitesi, Biyokimya Anabilim Dalı, Antalya, Türkiye 4AkdenizÜniversitesi Tıp Fakültesi, Kalp Damar Cerrahisi Anabilim Dalı, Antalya, Türkiye Yazışma Adresi Correspondence Address Hakan KESKİN Akdeniz Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, Antalya, Türkiye E-posta: [email protected]


Journal of Clinical and Analytical Medicine | 2014

Pseudochylothorax due to Rheumatoid Arthritis; A Very Rare Entity

Makbule Ergin; Ali Yeginsu; Kürşat Gürlek; İsmail Ergin

DOI: 10.4328/JCAM.729 Received:16.06.2011 Accepted: 11.08.2011 Printed: 01.01.2014 J Clin Anal Med 2014;5(1): 62-4 Corresponding Author: Makbule Ergin, Gaziosmanpasa Üniversitesi Tip Fakültesi, Gogus Cerrahisi Anabilim Dalı., Cennet Mh. 60500, Tokat, Turkey. F.: +90 3562133179 E-Mail: [email protected] Özet Pseudoşilotoraks genellikle tüberküloz veya romatoid artrit [RA] gibi kronik inflamatuar hastalıklarla ilişkilidir. RA’e bağlı pseudoşilotoraks çok daha nadir olup 2009’a kadar İngiliz literatüründe sadece 21 vaka vardır. Uzun süreli plevral efüzyon [5 yılın üzerinde] ampiyem ve pseudoşilotoraks ile sonuçlanabilir, ancak bizim hastalarımızın hikayeleri 2 ve 3 yıllıktı. Bu yazıda pseudoşilotoraks ve ampiyemli 2 RA vakasını literatüre katkı sağlaması ve pseudoşilotoraks tanısında zamanın bir kriter olmadığını vurgulamak için bildirdik.


Turkish journal of trauma & emergency surgery | 2013

[A rare complication after Velpeau bandage: hemopneumothorax].

Ali Yeginsu; Makbule Ergin; Kürşat Gürlek

Velpeau bandage is a treatment method that fixes the arm to the body in cases of fractures and dislocations at the region of shoulder. Velpeau bandage very rarely leads to complications. This case report involves a 45-year-old male admitted to the emergency service after trauma. Glenoid and multiple rib fractures were detected in radiological examinations. A transient Velpeau bandage was performed before surgical correction. Patient had dyspnea and chest pain 24 hours after bandage application. An obvious displacement at the rib fracture sites and hemopneumothorax were seen in the chest X-ray. A chest tube was inserted into the patient. Glenoid fracture was corrected surgically. Patient was discharged on the sixth day. He has no problems at readmission after the first month.


Turkish Journal of Surgery | 2010

Göğüs tüpü takılması

Makbule Ergin; Ali Yeginsu; Kürşat Gürlek

GIRIŞ Gogus tupu, kapali drenaj sistemleri yardimi ile plevral kavitenin tek yonlu drenajini saglar. Gogus tupu takilmasi (tup torakostomi) acil durumlarda potansiyel olarak hayat kurtarici bir girisimdir ve acil serviste calisan her hekim gerekli oldugunda uygulayabilecek duzeyde bilgi sahibi olmalidir. Gogus tupu takilmasinin esas amaci temelde plevral bosluktaki hava ya da sivinin (kan, lenf, pu ve diger) tahliyesini saglamaktir. Bununla birlikte tup icerisinden tedavi amacli degisik ilaclar plevral bosluga uygulanabilir (1,2).


Anz Journal of Surgery | 2007

OESOPHAGEAL BURST STRENGTH

Ali Yeginsu; Makbule Ergin; Unal Erkorkmaz

At the early phase of primary oesophageal closure, the mechanical integrity of repaired oesophageal part is very important for maintaining an airtight, water-tight barrier against gastric contents that direct access to the mediastinum and pleural cavity, leading to severe mediastinitis, empyema and ultimately multiorgan failure. Our purpose was to investigate the influence of the length of repaired oesophageal part on the oesophageal bursting strength. Sixty fresh sheep oesophagi were received from the local slaughterhouse. The specimens were randomly divided into three groups (n = 20). Two-centimetre, 4-cm and 6-cm longitudinal oesophagotomy incisions were carried out in the 1/3 distal portion of the oesophagi in group 1, 2 and 3, respectively. Interrupted mucosal–submucosal suture plus over–over continuous muscular suture pattern with 4-0 silk was used in all groups. Specimens were mounted a sphygmomanometer (Riester, Jungingen, Germany), distal end of oesophagi were clamped and subsequently positioned under water. The bursting pressure level at which we detected air bubbles indicated the limits of the technique. One-way ANOVA was used for the comparison of parametric data. For post-hoc multiple comparison, the Scheffe’s test was used. A P-value of less than 0.05 was considered significant. Six-centimetre primary repair has significantly less bursting strength than the other groups (171 – 49mmHg, P= 0.011). Two-centimetre and 4-cm primary repairs had nearly equal bursting strengths (211 – 47mmHg and 214– 48mmHg, respectively. P= 0.989). Statistical evaluation of the bursting pressures was indicated in Table 1. Our study showed that the length of primary oesophageal closure affects the oesophageal bursting strength. In particular, primary repairs that are 6 cm or longer have less bursting strength than the shorter ones. The most vulnerable period of the healing anastomosis is between days 4 and 7.1 At this period of oesophageal healing, establishing the mechanical integrity is crucial for maintaining an airtight, water-tight barrier against the gastric contents. The leakage may occur through suture holes or between sutures in gastrointestinal repair and this might be due not only to the anastomotic technique, but also to the differences of elongation of intestine and suture material.2 It may be concluded that in a longer suture line, the likelihood of leakage rises because of more longitudinal elongation of the suture line. Bursting strength measurement is an acceptable method, which assesses longitudinal and circular forces in hollow organs.3 In this ex vivo study, we used a sheep oesophagus because of its similarities with that of humans regarding the thickness and histological structure.4


Lung | 2008

Benign Metastasizing Leiomyoma

Feride Sapmaz; Makbule Ergin; Ozgur Katrancioglu; Tanseli Efeoglu Gonlugur; Ugur Gonlugur; Sahende Elagoz


Turkish Journal of Medical Sciences | 2011

The effects of local anaesthesia with bupivacaine and botulinum toxin-A after thoracotomy on stress hormone levels

Makbule Ergin; Ali Yeginsu; İsmail Kürşat Gürlek


Journal of Clinical and Analytical Medicine | 2011

Thalassemia Minor Presenting with Xiphodynia

Makbule Ergin; Ali Yeginsu

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Ali Yeginsu

Gaziosmanpaşa University

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Ayşe Yılmaz

Gaziosmanpaşa University

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Huseyin Ozyurt

Gaziosmanpaşa University

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