Makoto Takiguchi

Influence of donor condition on postoperative graft survival and function in human liver transplantation.

BODY condition of a brain death patient, such as blood electrolytes and cardiovascular system, is often unstable because of lack of homeostasis, experience of hypoxia, and multiple severe body injuries. Therefore, postoperative hepatic allograft function should be associated with general condition of cadaveric organ donor. For this reason, several retrospective analyses of donor variables have attempted to identify risk factors predictive of both patient and graft survival after liver transplantation. In the present study, we investigated influence of donor condition, including age, need for vasopressor, and serum sodium concentration, on early postoperative graft outcome in human liver transplantation by means of prospective collection of donor and recipient data.