Malai Haniti S.A. Hamid

Synthesis of cyclopropyl-substituted furans by brønsted Acid promoted cascade reactions.

Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position. Synthetically relevant polycyclic building blocks featuring rings of various sizes and heteroatoms have been synthesized in high yield using this mild acid-catalyzed reaction.

Octyl (2E)-2-[2-(di-phenyl-phosphan-yl)benzyl-idene]hydrazinecarbodi-thio-ate.

The title compound, C28H33N2S2P, adopts the thione tautomeric form, as supported by the C—S distance [1.6744 (18) Å]. The Schiff base exhibits an E conformation about the C=N bond but a Z conformation about the C—N bond. The terminal chain is disordered over two sets of sites with an occupancy ratio of 0.732 (3):0.268 (3). In the crystal, pairs of N—N—H hydrogen bonds between the thione groups link neighbouring molecules into centrosymmetric dimers.

(1E,2E)-1,2-Bis(2,3,4-trimeth­oxy­benzyl­idene)hydrazine

The title compound, C20H24N2O6, was obtained as an unexpected product by the reaction of hydrazinium dithiocarbazate with 2,3,4-trimethoxybenzaldehyde in refluxing ethanol. The molecule lies on a center of inversion. The crystal packing is stabilized by weak intermolecular C—H⋯O interactions.