Malai Muttarak

Spectrum of Papillary Lesions of the Breast: Clinical, Imaging, and Pathologic Correlation

OBJECTIVE Papillary lesions of the breast are a heterogeneous group of lesions that are difficult to diagnose as benign or malignant. The purpose of this article is to review clinical presentation, imaging features, and pathologic correlation of papillary lesions of the breast and to discuss the prognosis and management of these lesions. CONCLUSION Recognition of the variety of benign and malignant papillary lesions of the breast will facilitate diagnosis and proper management.

Tuberculosis arthritis and tenosynovitis.

The incidence of extrapulmonary tuberculosis (TB) has been rising due to the increasing number of immunosuppressed patients. Musculoskeletal system accounts for 25% of extrapulmonary TB. Most of the musculoskeletal TB involves the spine. TB of peripheral joints and tendons occur infrequently, but if untreated, it can cause serious joint and tendon destruction as well as spread of the infection to the surrounding bursa, muscle, and other soft tissues. The diagnosis of TB of joints and tendons is difficult due to the nonspecific clinical manifestations and imaging features. Concurrent active pulmonary TB is present in <50% of the patients. A positive chest radiographic finding or a positive tuberculin test supports the diagnosis, but negative results do not exclude diagnosis. Although imaging features of TB of joints and tendons are nonspecific, certain findings such as relatively preserved joint space, juxta-articular osteoporosis, cold abscesses, para-articular soft tissue calcification, and rice bodies are suggestive of TB infection. Familiarity with these imaging features can help in making an early diagnosis and facilitating proper management.

Multiple Bilateral Giant Fibroadenomas Associated with Cyclosporine a Therapy in a Renal Transplant Recipient

A 31-year-old woman developed a right breast mass following cyclosporine A therapy after a renal transplant. Several large breast masses continued to grow bilaterally. Mammography and ultrasonography showed features of giant fibroadenomas. The diagnosis was confirmed by biopsy of one of the masses. Awareness of the association between cyclosporine A therapy and fibroadenoma development in renal transplant recipients is highlighted.

Pitfalls in imaging of musculoskeletal infections.

In musculoskeletal infections, imaging helps in the diagnosis and identification of disease extent. Musculoskeletal infections have variable clinical presentations related to host immune responses and virulence of pathogens. Occasionally, infectious process may mimic other entities such as autoimmune inflammatory diseases, tumors, or traumatic injuries, both clinically and radiologically. Identification of the disease extent is sometimes difficult, particularly when infection occurs in the damaged tissue. The key imaging feature of infection is formation of abscesses. Familiarity of the imaging patterns of the infectious process leads to correct diagnosis and appropriate treatment.

Malignant Breast Tumors

Breast cancer is a commonly diagnosed malignancy in women, and its incidence increases with age. This chapter presents the most common types of breast cancer encountered in geriatric patients, including invasive ductal carcinoma, invasive lobular carcinoma, mucinous carcinoma, ductal carcinoma in situ, and papillary carcinoma. Since the incidence of breast cancer in men also increases with age, a section on male breast cancer is included. The imaging features of each entity are discussed. The role of imaging for the accurate staging of breast cancer is discussed, and an overview of the treatment of elderly breast cancer patients is provided, including information regarding surgery and radiation therapy, endocrine or hormonal therapy, and systemic chemotherapy.

Clinics in diagnostic imaging (149)

A 33-year-old man presented with a painless, non-growing left testicular mass for five years. Preoperative ultrasonography (US) of the scrotum showed a small, circumscribed calcific mass in the right testis and another well-defined heterogeneous echoic mass with a partially calcified wall in the left testis, with avascularity on colour Doppler US. These imaging findings in a clinical setting of non-growing testicular masses were highly suggestive of epidermoid cysts, thus leading to testis sparing surgery. Histopathology confirmed bilateral epidermoid cysts. To the best of our knowledge, only 15 cases of bilateral epidermoid cysts have been reported. We discuss the US features of epidermoid cyst and its surgical management, as well as various cases of testicular masses.

Noninvasive Assessment of Patency of Internal Ureteral Stent: Role of Colour Doppler Ultrasound

OBJECTIVE To compare colour Doppler ultrasonography (CDU) and retrograde cystography in the assessment of the patency of internal ureteral stents. PATIENTS AND METHODS Thirty-two patients with 33 internal ureteral stents were evaluated for patency of the internal ureteral stent using both CDU and retrograde cystography. Real-time ultrasonography and CDU were performed before retrograde cystography. Stent patency was defined as seeing flow from the distal end of the stent in the urinary bladder or iodinated contrast in the renal pelvis. The two investigators had no prior knowledge of the others results. After completion of both investigations, stent patency was proved by direct inspection of the stent after removal. RESULTS Both investigations showed the same result in 27 of the 33 stents. Stent patency was found if either investigation was positive. The accuracies of retrograde cystography, CDU and both were 73%, 79% and 85%, respectively. CONCLUSIONS CDU is a noninvasive method with high accuracy. Detection of flow at the distal end of the stent is helpful, but absence of flow may or may not indicate an obstructed stent and further investigation should be performed.