Malcolm Stuart Nobbs
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Featured researches published by Malcolm Stuart Nobbs.
Bioorganic & Medicinal Chemistry Letters | 1993
Paul Barraclough; James W. Black; David Cambridge; V. Paul Gerskowitch; Heather Giles; Robert C. Glen; Robert A. D. Hull; W. Richard King; Malcolm Stuart Nobbs; Peter Randall; Gita P. Shah; David Stone; Susan J. Vine; Mark V. Whiting
A series of 2-aryl imidazo[1,2-a]pyrazines has been prepared and evaluated for inotropic activity. Sulphoxide 12, BW315C, displayed potent inotropic effects having comparable in vitro and vivo inotropic potencies to those of isomazole. Structure-activity relationships are discussed.
Journal of Chemical Research-s | 1997
Paul Barraclough; W. Richard King; Malcolm Stuart Nobbs; Susan J. Vine; Janet M. Gillam
The base-catalysed hydrolysis of oxazolidin-2-one 15 gives an oxypropanolamine 7 and 4,5-dihydro-1H-imidazo[4,5-c]pyridin-4-ones (17–19) and may occur by a B AL mechanism.
Archive | 1989
Alistair Ainslie Miller; Malcolm Stuart Nobbs; Richard M. Hyde; Michael John Leach
Magnetic Resonance in Chemistry | 1991
Paul Barraclough; David Firmin; John C. Lindon; Malcolm Stuart Nobbs; Paul N. Sanderson; Steven Smith; Janet M. Gillam
Archive | 1995
Alistair Ainslie Miller; Malcolm Stuart Nobbs; Richard M. Hyde; Michael John Leach
Magnetic Resonance in Chemistry | 1989
Paul Barraclough; John C. Lindon; Malcolm Stuart Nobbs; J. M. Williams
Archive | 1995
Alistair Ainslie Miller; Malcolm Stuart Nobbs; Richard Martin Hyde; Michael John Leach
Archive | 1986
Paul Barraclough; Steven Smith; Malcolm Stuart Nobbs
Archive | 1998
Brian Cox; Mark Patrick Healy; Malcolm Stuart Nobbs; Gita P. Shah
Archive | 1995
Alistair Ainslie Miller; Malcolm Stuart Nobbs; Richard Martin Hyde; Michael John Leach