Manki Komatsu

Two flavanones in Sophora leachiano and some related structures

Abstract A novel flavanone, leachianone A, with a lavandulyl residue was isolated from the roots of Sophora leachiano in addition to sophoraflavanone G. The structure was determined to be 5,7,4′-trihydroxy-8-lavandulyl-2′-methoxyflavanone by means of NMR ( 1 H- 1 H and 1 H- 13 C COSY) spectral analysis. The structural relationships of leachianone A with isokurarinone and vexibidin, and of sophoraflavanone G and kushenol F with nor -kurarinone and vexibinol are also discussed.

Four isoflavanones from roots of Sophora tetraptera

Four new isoflavanones, tetrapterols F–I, were isolated from roots of Sophora tetraptera in addition to seven known flavonoids, lupinifolin, 8-O-methylretusin, 5,7,4′-trihydroxy-6,3′-di(γ,γ-dimethylallyl)isoflavone, (−)-maackiain, sophoracarpan A, medicagol and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran. The structure of the new isoflavanones was determined to be 3,5,7–trihydroxy-2′-methoxy-8-γ,γ-dimethylallyl-6‴,6‴-dimethylpyrano[2‴,3‴:4′,3′]isoflavanone(tetrapterol F), 5,7,2′,4′-tetrahydroxy-6,5′-di(γ,γ-dimethylallyl)isoflavanone(tetrapterol G), 5,7,2′–trihydroxy–4′–methoxy-8,5′-di(γ,γ-dimethylallyl) isoflavanone(tetrapterol H) and 7,4′-dihydroxy-6,3′-di(γ,γ-dimethylallyl)isoflavanone (tetrapterol I) by means of spectroscopic analysis.

Isoflavonoids from Sophora secundiflora, S. arizonica and S. gypsophila

Abstract Eight new isoflavonoids, secundiflorols G-I and arizonicanols A-E, were isolated from the stem of Sophora secundiflora and the root of S. arizonica and S. gypsophila and the structures were determined by spectral analysis. The similarity of flavonoid occurrence was found in the three species. From the chemosystematic standpoint, the subgenus Styphnologbium seems to be composed of two chemical types ( S. secundiflora, S. arizonica , and S. gypsophila vs S. japonica and S. affinis ).