Manoj Kumar Tripathi

Standardization of Stamens of Mesua ferrea Linn.

India has a rich culture of medicinal herbs and spices, which includes Ayurvedic, Unani, Siddha and other traditional medicines but only very few have been studied chemically and pharmacognostically evaluated for their potential medicinal value. According to the World Health Organization, most populations still rely on traditional medicines for their psychological and physical health requirements. Nagkesar is a very famous ayurvedic herb used in treating fever, vomiting, urinary tract disorders, migraine and also used to preparation of several compound formulation viz. Candanabalalaksadi Taila, Kumaryasava, Nagakesaradi Curna, Kankasava, Eladi curna, Jatiphaladi curna and Karpuradi churna etc. The present paper provides a detailed account of the scientific evaluation of Mesua ferrea stamens. The study includes macro and microscopic characters, powder microscopic characteristics, High Performance Thin Layer Chromatography fingerprint profile, preliminary phytochemical screening and physicochemical parameters. The information generated by this particulars study provides relevant pharmacognostical and physicochemical data needed for proper identification and authentication of Mesua ferrea stamens.

HPTLC Fingerprint Profile and Preliminary Phyto-chemical analysis of Nimba (Azadirachta indica) Leaf and Stem Bark

Medicinal plants have been found useful in the cure of a number of diseases including bacterial diseases. Nimba is a very useful medicinal plant in the sub-continent and each part of the plant has medicinal properties. Almost every part of the plant has been in use since ancient times to treat a number of human ailments and also as a household pesticide. The extract from bark, leaves, fruits and root have been used to control leprosy, intestinal helminthiasis and respiratory disorders in children. Flavonoids, flavonoglycosides, dihydrochalcones, tannins and others are also important constituents of bark, leaves, fruits and flowers of Nimba. Present study aimed development and establishment of the HPTLC fingerprint profile and phytochemical screening of Nimba leaf and stem bark.

Standardization of Ayurvedic polyherbal formulation, Kutajastaka Pravahi Kvatha

Ayurvedic medicine Kutajastaka Pravahi Kvatha, known to be effective in Daha (burning sensation); Raktatisara (Diarrhoea with blood); Sula (pain); Amadosa; (products of impaired digestion and metabolism) and Sarvatisara (all types of diarrhoea), has been standardized by following modern scientific quality control procedures for the finished product. The results of physico-chemical parameters viz. specific gravity (1.01), total solids (4.45%) and pH (4.50) were found. Microbiological limit test and heavy metals Pb, Cd, As, Hg were also found within the limits set by Ayurvedic Pharmacopiea of India (API). The obtained values can be adapted to lay down new pharmacopoeial standards with batch to batch consistency. The phytochemical constituents found in the raw material used for the preparation of Kutajastaka Pravahi Kvatha facilitate the desirable therapeutic efficacy of the medicinal formulations a whole in elements and also could help in understanding the underlying mechanism of pharmacological action.