Manuel Javier Cases-Thomas
Eli Lilly and Company
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Publication
Featured researches published by Manuel Javier Cases-Thomas.
Journal of Organic Chemistry | 2010
Philip D. Dorgan; Jamie Durrani; Manuel Javier Cases-Thomas; Alison N. Hulme
The low-temperature Evans-Tishchenko coupling of a range of functionalized heteroaryl aldehydes with β-hydroxy ketones in the presence of a Sm(III) catalyst has been achieved with high yields (90-99%) and good to excellent diastereoselectivity (90:10 → 95:5 dr). However, at room temperature a retro-aldol aldol-Tishchenko reaction was found to compete with the desired Evans-Tishchenko reaction. Identification of these byproducts has allowed the corresponding aldol-Tishchenko reaction to be optimized for several heteroaryl aldehydes.
Archive | 2006
John Gordon Allen; Karin Briner; Anne Marie Camp; Manuel Javier Cases-Thomas; Richard Charles Hoying; Maria Angeles Martinez-Grau; Michael Philip Mazanetz; Natalia Pokrovskaia; Richard Edmund Rathmell; Roger Ryan Rothhaar; Selma Sapmaz; Andrew Caerwyn Williams
Archive | 2006
Karen Briner; Manuel Javier Cases-Thomas; Marta Adeva Bartolome; Christopher Stanley Galka; Alicia Marcos Llorente; Maria Angeles Martinez-Grau; Michael Philip Mazanetz; John Cunningham O'toole; Richard Edmund Rathmell; Matthew Robert Reinhard; Selma Sapmaz; Andrew Caerwyn Williams
Archive | 2004
Christopher David Beadle; Manuel Javier Cases-Thomas; Barry Peter Clark; Peter Thaddeus Gallagher; John Joseph Masters; Graham Henry Timms; Magnus Wilhelm Walter; Maria Ann Whatton; Virginia Ann Wood; Jeremy Gilmore
Archive | 2004
Gordon Iain Campbell; Manuel Javier Cases-Thomas; Teresa Man; John Joseph Masters; Hélène Catherine Eugénie Rudyk; Magnus Wilhelm Walter
Archive | 2004
Christopher David Beadle; Manuel Javier Cases-Thomas; Barry Peter Clark; Peter Thaddeus Gallagher; John Joseph Masters; Graham Henry Timms; Magnus Wilhelm Walter; Maria Ann Whatton; Virginia Ann Wood; Jeremy Gilmore
Archive | 2003
Manuel Javier Cases-Thomas; Helen Louise Haughton; Carlos Lamas-Peteira; Sivi Ouwerkerk-Mahadevan; John Joseph Masters; Robin George Simmonds; Hélène Catherine Eugénie Rudyk; Magnus Wilhelm Walter
Archive | 2006
Karin Briner; Bartolome Marta Adeva; Manuel Javier Cases-Thomas; Christopher Stanley Galka; Llorente Alicia Marcos; Maria Angeles Martinez-Grau; Michael Philip Mazanetz; John Cunningham O'toole; Richard Edmund Rathmell; Matthew Robert Reinhard; Selma Sapmaz; Andrew Caerwyn Williams
Archive | 2004
Gordon Iain Campbell; Manuel Javier Cases-Thomas; Teresa Man; John Joseph Masters; Hélène Catherine Eugénie Rudyk; Magnus Wilhelm Walter
Archive | 2004
Christopher David Beadle; Manuel Javier Cases-Thomas; Barry Peter Clark; Peter Thaddeus Gallagher; John Joseph Masters; Graham Henry Timms; Magnus Wilhelm Walter; Maria Ann Whatton; Virginia Ann Wood; Jeremy Gilmore
