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Dive into the research topics where Marc Whitlow is active.

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Featured researches published by Marc Whitlow.


Cancer | 1997

Single chain antigen binding protein (sFv CC49)

Steven M. Larson; Ayda M. El-Shirbiny; Chaitanya R. Divgi; George Sgouros; Ronald D. Finn; Jorg Tschmelitsch; Antonio Picon; Marc Whitlow; Jeffrey Schlom; Jiaju Zhang; Alfred M. Cohen

An sFv fragment of the anti‐TAG‐72 monoclonal antibody CC49 has been developed and has shown promise in improved targeting to colorectal carcinoma in animal studies. In this study the authors report their initial experience in human patients after intravenous injection.


Archive | 1992

Multivalent antigen-binding proteins

Marc Whitlow; James F. Wood; Karl D. Hardman; Robert E. Bird; David Filpula; Michele L. Rollence


Cancer Research | 1992

Rapid Tumor Penetration of a Single-Chain Fv and Comparison with Other Immunoglobulin Forms

Takashi Yokota; Diane E. Milenic; Marc Whitlow; Jeffrey Schlom


Cancer Research | 1991

Construction, Binding Properties, Metabolism, and Tumor Targeting of a Single- Chain Fv Derived from the Pancarcinoma Monoclonal Antibody CC49

Diane E. Milenic; Takashi Yokota; David Filpula; M. A. J. Finkelman; S. W. Dodd; James F. Wood; Marc Whitlow; P. Snoy; Jeffrey Schlom


Archive | 1997

Linker and linked fusion polypeptides

Marc Whitlow; David Filpula


Archive | 1998

Polyalkylene oxide-modified single chain polypeptides

Marc Whitlow; Robert G. L. Shorr; David Filpula; Lihsyng Standford Lee


Protein Engineering | 1994

Multivalent Fvs: characterization of single-chain Fv oligomers and preparation of a bispecific Fv

Marc Whitlow; David Filpula; Michele L. Rollence; Sheau-Line Feng; James F. Wood


Cancer Research | 1993

Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms

Takashi Yokota; Diane E. Milenic; Marc Whitlow; James F. Wood; Steven L. Hubert; Jeffrey Schlom


Archive | 1998

Single-chain antigen-binding proteins capable of glycosylation, production and uses thereof

David Filpula; Maoliang Wang; Robert G. L. Shorr; Marc Whitlow; Lihsyng S. Lee


Protein Engineering | 1995

1.85 Å structure of anti-fluorescein 4-4-20 Fab

Marc Whitlow; Andrew Howard; Jay F. Wood; Edward W. Voss; Karl D. Hardman

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