Marcel Bertrand

Sur une possibilite d'acces aux cetones macrocycliques par les ene-allenes

Abstract Ene-allenes can be valuable precursors for the obtention of bicyclic enones, key-intermediates for the synthesis of macrocyclic ketones like exaltone and muscone.

Allene oxide. V - oxidation of β-allenic alcohols bearing a trimethylsilyl group on the allenic moiety. Probe of a concerted mechanism in the δ-lactones formation.

Abstract β-allenic alcohols substituted by a trimethylsilyl group at the −1 or −3 position respectively give rise to γ or δ-lactones. In the last case, a concerted mechanism is involved

cis Δ5-octahydro-1-naphtalenones and cis Δ5-decahydro-1-naphthalenes (cis-1-decalones) by stereoselective intramolecular diels-alder reaction.

Abstract Intramolecular DIELS-ALDER reactions of requisite trienes led to cis -1-decalones, via an endo intermediate state.

Sur la réaction de l'iodure de triméthylsilyle avec les alcools acétyléniques

Abstract Iodotrimethylsilane reacts with propargyl alcohols to give unsaturated halohydrins or unsaturated alkyl diiodides.

Transfert de chiralite par hetero-ene synthese intramoleculaire

Abstract The first example of transfer of axial chirality into central chirality during a reaction of hetero-ene synthesis performed with optically active γ-allenic aldehyde is reported.