Marcela Concha R

Tuberculosis cutánea: reporte de dos casos y revisión de la literatura

Cutaneous tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis. It is uncommon (1% of all cases of tuberculosis), but has increased due to the human immunodeficiency virus epidemic and to pharmacologic immunosuppression. It presents a wide variety of clinical forms depending on how bacteria reach the skin and on the immune status of the patient. We present two cases of cutaneous tuberculosis diagnosed in the Hospital Clinico de la Pontificia Universidad Catolica de Chile. We emphasize the difficulty in diagnosis and classification of this disease and briefly discuss on the different diagnostic and therapeutic approaches.

Diagnóstico y terapia del virus papiloma humano

The identification and treatment of human papillomavirus (HPV) infections and HPV-associated neoplasm are complex. Difficulties in diagnosis and treatment of HPV-associated diseases arise from inabilities to detect HPV efficiently, the lack of specific antiviral drugs active against HPV and the high rates of recurrence and persistence of HPV infections after treatment. We present a review of therapies for HPV infections.

Enfermedad de Hansen: Revisión a propósito de un caso

Leprosy is a granulomatous disease affecting the skin and peripheral nerves caused by Mycobacterium leprae. The range of clinical forms varying from tuberculoid to lepromatous leprosy results from variations in the cellular immune response to the mycobacterium. Despite available combined drug-therapy, it continues to be a significant public health problem, carrying a strong stigma. Although recently there has been no native cases in Chile, a few imported cases have been diagnosed. We present a 56-year-old man who had lived in Paraguay for 8 years, and presented with leprosy 6 years after returning to Chile. The biology of leprosy, clinical features of the disease, current diagnostic criteria and approaches to treatment are discussed.

Septicemia neonatal: incidencia, letalidad y caracteristicas bacteriologicas. Comparacion de dos periodos

Resumen Objetivos: describir y comparar la incidencia y letaiidad de ia septicemia neonatal, en dos periodos en unhospital unive r sitario. Padentes y rnetodo: se compararon reden nacidos que tuvieron septicemia entre los rneses deJulio de 1987 a junio de 1989 con los del periodo de enero de 1995 a dicembre de 1996. Resultados: la inciden-cia de septicemia neonaral aumento (2,9 a 8,7 por mil] y la letalidad (44% a 2,2%) disminuyo en el segundoperiodo. Las poblacones estudiadas y los metodos de diagnostico fueron sirnilares. En las septicemias connotates elgerrnen preponderante fue el Srreptococcus grupo 3 sin diferencias entre periodos [50% ante 52%). Entre lassepticemias nosocomiales, aumentcron las producidas por estafilococo (desde 25% a 91%], siendo Siaphylococcusepidermidis devino el principcf agente durante el segundo periodo (57% del total), disminuyendo la sensibilidad acloxacilina (100% a 33%). Conclusiones: se demuestra un aumento de la incidencia y mejoria del pronostico de lassepticemias neonatales con un cambio en sus caracterislicas bacteriologicos entre los periodos estudiados, similar alo observado en otros paises.(Palabras clave: recien nacidos, septicemia.)

Remisión de la psoriasis luego de bypass gástrico

Resumen es: La psoriasis es una patologia dermatologica frecuente que afecta entre 1 al 3% de la poblacion. Estudios recientes han identi fi cado mayor indice de obe...