Marcia W. Legro
Johns Hopkins University
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Ophthalmology | 1992
Jonathan C. Javitt; James M. Tielsch; Joseph K. Canner; Margaret M. Kolb; Alfred Sommer; Earl P. Steinberg; Marilyn Bergner; Gerard F. Anderson; Eric B Bass; Alan M. Gittelsohn; Marcia W. Legro; Neil R. Powe; Oliver P. Schein; Phoebe Sharkey; Donald M. Steinwachs; Debra A. Street; Donald J. Doughman; Merton Flom; Thomas S. Harbin; Harry L.S. Knopf; Thomas Lewis; Stephen A. Obstbaum; Denis M. O'Day; Walter J. Stark; Arlo C. Terry; C. Pat Wilkinson
PURPOSE The authors studied 57,103 randomly selected Medicare beneficiaries who underwent extracapsular cataract extraction in 1986 or 1987 to determine the possible association between performance of neodymium (Nd):YAG laser capsulotomy and the risk of subsequent retinal break or detachment. METHODS Cases of cataract surgery were identified from Medicare claims submitted in 1986 and 1987 and were followed through the end of 1988. Episodes of cataract surgery, posterior capsulotomy, and retinal complications were ascertained based on procedure and diagnosis codes listed in physician bills and hospital discharge records. Lifetable and Coxs proportional hazards models were used to analyze the risk of retinal detachment or break in patients undergoing and not undergoing capsulotomy during the period of observation. RESULTS Of the 57,103 persons identified as having undergone extracapsular cataract extraction in 1986 or 1987, 13,709 subsequently underwent Nd:YAG laser capsulotomy between 1986 and 1988. A total of 337 persons had aphakic or pseudophakic retinal detachments between 1986 and 1988 and an additional 194 underwent repair of a retinal break. Proportional hazards modeling shows a 3.9-fold increase in the risk of retinal break or detachment among those who underwent capsulotomy (95% confidence interval: 2.89 to 5.25). Younger patient age, male sex, and white race also were associated with increased risk of retinal complications after extracapsular cataract extraction. CONCLUSION The authors conclude that there is a statistically significant increase in the risk of retinal detachment or break in those patients who undergo capsulotomy after cataract extraction. Therefore, capsulotomy should be deferred until the patients impairment caused by capsular opacification warrants the increased risk of retinal complications associated with performance of capsulotomy.
Journal of Behavioral Medicine | 1993
Barbara Curbow; Mark R. Somerfield; Frank Baker; John R. Wingard; Marcia W. Legro
We investigated the number and direction of personal changes experienced by long-term survivors of bone marrow transplantation (BMT) and the relationships of those changes and dispositional optimism to psychological adjustment (current and future life satisfaction and mood). Surveys were returned by 86.0% (N=135) of all eligible long-term survivors; respondents primarily were young males who were 6 to 149 months post-BMT. Subjects reported more positive changes in the relationship and existential/psychological domains and more negative changes in the physical health domain; there was no difference on the plans/activities domain. Negative changes were more strongly related to adjustment than were positive changes. The number of negative changes reported was significantly related to current and future life satisfaction and negative mood after controlling for demographic and illness variables and dispositional optimism. The interaction term for negative and positive changes was significantly related to future life satisfaction after controlling for all other variables.
Ophthalmology | 1994
Jonathan C. Javitt; Debra A. Street; James M. Tielsch; Qin Wang; Margaret M. Kolb; Oliver D. Schein; Alfred Sommer; Marilyn Bergner; Earl P. Steinberg; Gerard F. Anderson; Eric B Bass; Joseph K. Canner; Alan M. Gittelsohn; Marcia W. Legro; Neil R. Powe; Oliver P. Schein; Phoebe Sharkey; Donald M. Steinwachs
Background: A near-total shift to cataract extraction on an outpatient basis occurred as a result of an administrative ruling by the Health Care Financing Administration. No national study has been conducted to assess the possible effects of that decision on clinical outcomes of surgery. The authors compared the rates of retinal detachment (RD) repair and hospitalization for endophthalmitis after extracapsular cataract extraction (ECCE) (including phacoemulsification) in 1986 and 1987 with those following inpatient cataract extraction in 1984. Methods: Using the 5% random sample of Medicare beneficiaries, we analyzed the claims of all individuals 66 years of age or older who underwent ECCE by nuclear expression or phacoemulsification in 1986 and 1987. A total of 57,103 patients were identified and followed to the end of 1988. Cumulative probability of RD repair and hospitalization for endophthalmitis was calculated by standard lifetable methods. These findings were compared with the cumulative probability of the same complications in a cohort of 330,000 patients who underwent cataract extraction on an inpatient basis in 1984. Results: In the 1986-to-1987 cohort, the cumulative probability of RD within 3 years after cataract surgery was 0.81% and the cumulative probability of endophthalmitis within 1 year was 0.08%. The rate of RD is similar to that which we previously reported for 330,000 patients who underwent inpatient surgery in 1984, but the rate of endophthalmitis is significantly lower in the 1986-to-1987 outpatient cohort (0.08% versus 0.12%; z = 2.42; P = 0.01). Conclusions: The shift to outpatient cataract surgery was accompanied by no significant increase in the probability of RD repair and possibly a significant decrease in the rate of hospitalization for endophthalmitis.
Ophthalmology | 1994
Oliver D. Schein; Earl P. Steinberg; Jonathan C. Javitt; Sandra D. Cassard; James M. Tielsch; Donald M. Steinwachs; Marcia W. Legro; Marie Diener-West; Alfred Sommer
PURPOSE To examine associations between surgical technique, patient and surgeon characteristics, and clinical outcomes of cataract surgery. METHODS Seventy-five ophthalmologists were recruited from three cities based on a sampling scheme stratified by surgeon-reported annual volume of cataract surgery. Seven hundred seventy-two patients undergoing first eye cataract surgery were enrolled, with complete preoperative, perioperative, and 4-month postoperative clinical data on 717 patients (93%). RESULTS Sixty-five percent of surgery was performed by phacoemulsification and 35% by standard extracapsular (ECCE) techniques. Performance of ECCE was associated with the presence of ocular comorbidity and 21 or more years in practice of the surgeon. Performance of phacoemulsification was associated with annual volume of cataract surgery, wherein high-volume (201-399 patients annually) and very high-volume (> 400 patients annually) surgeons had 3.7 and 3.9 times the likelihood of performing phacoemulsification compared with moderate-volume (51-200 cases annually) surgeons. The rates of intraoperative, perioperative, and 4-month postoperative adverse events and the amount of improvement in visual acuity did not differ either by surgical technique or volume stratum. The reported occurrence of posterior capsular opacification within 4 months of surgery was increased in the presence of cortical opacification, one city, and patients operated on by either high- or very high-volume surgeons. CONCLUSIONS In this cohort, no difference in clinical outcomes, as measured by change in visual acuity or occurrence of postoperative adverse events (except for posterior capsular opacification), can be attributed to performance of phacoemulsification versus ECCE or to the reported annual volume of cataract surgery of the surgeon. Self-reported high and very high annual volume of cataract surgery is associated independently with performance of phacoemulsification and surgeons report of posterior capsular opacification at 4 months after cataract surgery.
Social Science & Medicine | 1990
Barbara Curbow; Mark R. Somerfield; Marcia W. Legro; John Sonnega
Research and theory development on the self-concept have increased dramatically over the last decade. Investigators of the psychosocial aspects of cancer have utilized the self-concept as both an independent and dependent variable. This article discusses quantitative adult studies from the self-concept and cancer literature in terms of their correspondence with current conceptualizations of the self-concept in psychology. The wide gap between recent empirical work and self-concept theorizing is discussed and strategies for future investigations of the self-concept/cancer relationship are outlined.
Journal of Psychosocial Oncology | 1993
Barbara Curbow; Marcia W. Legro; Frank Baker; John R. Wingard; Mark R. Somerfield
This article presents findings on how survivors of an intensive treatment for cancer-bone marrow transplantation (BMT)- conceptualize and describe their current lives. The presence of 11 themes of loss (e.g., loss of reproductive capability) and 11 themes of recovery (e.g., finding new meaning in life) were rated from statements made by 135 survivors of BMT in response to items from an in-depth, structured questionnaire. No significant differences were found in the frequency of themes of loss versus recovery. A classification of respondents revealed that 26.7 percent focused more on loss, 21.5 percent focused more on recovery, and 51.8 percent had a balanced view of their lives. The frequencies of specific loss and recovery themes were related to gender, age at BMT, marital status, and time since BMT. The authors discuss the possibility that subgroups of survivors, on the basis of life stage, find different routes to recovery.
Archives of Ophthalmology | 1994
Earl P. Steinberg; James M. Tielsch; Oliver D. Schein; Jonathan C. Javitt; Phoebe Sharkey; Sandra D. Cassard; Marcia W. Legro; Marie Diener-West; Eric B Bass; Anne M. Damiano; Donald M. Steinwachs; Alfred Sommer
Ophthalmology | 1994
Earl P. Steinberg; James M. Tielsch; Oliver D. Schein; Jonathan C. Javitt; Phoebe Sharkey; Sandra D. Cassard; Marcia W. Legro; Marie Diener-West; Eric B Bass; Anne M. Damiano; Donald M. Steinwachs; Alfred Sommer
Ophthalmology | 1991
Jonathan C. Javitt; James M. Tielsch; Joseph K. Canner; Margaret M. Kolb; Alfred Sommer; Earl P. Steinberg; Marilyn Bergner; Gerard F. Anderson; Eric B Bass; Alan M. Gittelsohn; Marcia W. Legro; Neil R. Powe; Oliver P. Schein; Phoebe Sharkey; Donald M. Steinwachs; Debra A. Street; Donald J. Doughman; Merton Flom; Thomas S. Harbin; Harry L.S. Knopf; Thomas Lewis; Stephen A. Obstbaum; Denis M. O'Day; Walter J. Stark; Arlo C. Terry; C. Pat Wilkinson
Archives of Ophthalmology | 1993
Earl P. Steinberg; Jonathan C. Javitt; Phoebe Sharkey; Alan Zuckerman; Marcia W. Legro; Gerard F. Anderson; Eric B Bass; Denis M. O'Day