Marcus Droege

PDB10 A COMPARISON OF ECONOMIC OUTCOMES BETWEEN ADHERENT AND NONADHERENT PATIENTS TREATED WITH ORAL ANTIDIABETIC MEDICATIONS

Objectives: Healthcare costs for adherent patients were compared with costs for nonadherent patients in a cohort with diabetes mellitus taking metformin, sulfonylureas, or pioglitazone. Methods: Using both the commercial and Medicare supplemental MEDSTAT MarketScan® research databases, a retrospective cohort study identified 108,592 continuously insured patients 18 to 90 years of age with diabetes mellitus (ICD-9-CM 250.xx) using metformin, sulfonylureas, or pioglitazone monotherapy during 2003. Adherence was calculated in 2004 and 2005 using a medication possession ratio, and dichotomized at ≥80% to indicate adherence. Total healthcare costs included insurer payments and patient cost-sharing from medical (inpatient, outpatient) and prescription drug claims. Diabetes-specific costs included pharmacy claims for any diabetes drug and medical claims containing a primary diagnosis of diabetes or a diabetes complication. Multivariate analysis was conducted to adjust for potential confounders. Results: During the initial year of follow-up, the proportion of patients adherent to treatment were 57%, 61%, and 59% for metformin, sulfonylureas, anad pioglitazone, respectively. Annual unadjusted total healthcare costs were consistently lower for adherent patients than for non-adherent patients (

Comparing the T scores from bone sonometer measurements in Hispanic and non-Hispanic white women

1,470 less for metformin users,

Evaluating the Instructional Design of a Web-enhanced Educational Program for the Practice of Pharmaceutical Care

3,734 less for sulfonylurea users, and

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3,477 for pioglitazone users). In the multivariate models, total healthcare costs and diabetes specific healthcare costs respectively were

The uses and benefits of cluster analysis in pharmacy research.

846 (95% CI

Curricula Then and Now—An Environmental Scan and Recommendations Since the Commission to Implement Change in Pharmaceutical Education: Report of the 2006-2007 Academic Affairs Committee

747 to

Methodological challenges surrounding direct-to-consumer advertising research—The measurement conundrum

945) and

Pharmacists as Care Providers: Personal Attributes of Recent Pharmacy Graduates

55 (95% CI

Examining gender salary disparities: an analysis of the 2003 multistate salary survey

33 to

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77) per year lower for adherent patients compared to nonadherent patients. The adjusted annual adherence-related cost difference was