Margaret N. Coryell

METABOLISM OF WOMEN DURING THE REPRODUCTIVE CYCLE. XVII. CHANGES IN ELECTROPHORETIC PATTERNS OF PLASMA PROTEINS THROUGHOUT THE CYCLE AND FOLLOWING DELIVERY

The present investigation, an electrophoretic study of blood proteins, was planned to obtain information concerning the preconceptional physiologic status of women, the physiologic changes in the maternal organism in preparation for the exigencies of labor and losses at delivery, for the readjustment during the puerperium, and the demands of lactation. The results of this study will provide the basis for a better understanding of electrophoretic determinations of the proteins in the blood of women whose child-bearing was com

Plasma Proteins in Venous and Cord Blood at Delivery Following Uncomplicated and Complicated Pregnancies

Summary 1. Total protein, albumin, and 5 globulin fractions were determined by electrophoresis in the plasma of samples of cord blood and of venous blood from 11 women whose pregnancies were uncomplicated. Similar samples were obtained for electrophoretic analysis from 21 women whose pregnancies were complicated by toxemia of pregnancy and other diseases. 2. For the samples representing uncomplicated pregnancy total protein values for venous blood were higher than for cord blood. Greater average amounts of albumin and gamma globulin were found in cord blood than in the corresponding venous blood, coincident with lesser amounts of alpha, beta, and phi globulins. 3. In complicated pregnancies the ranges for total plasma protein in venous and cord blood were lower than for the normal group. Ranges of values for serum protein (calculated as plasma minus fibrinogen) fractions in cord blood following complicated pregnancies were, in general, higher for albumin and gamma globulin and lower for alpha, beta, and phi globulins than the ranges for venous blood.

Composition of the human placenta: III Vitamin content

Abstract For nine human placentas the average fresh weight was 583 Gm., the dry weight was 72 Gm. The average content of total thiamine was 256 migrograms; of free thiamine, 84 mmg.; total riboflavin, 820 mmg.; free riboflavin, 296 mmg.; niacin, 1.99 mg.; pantothenic acid, 1,535 mmg.; firmly bound biotin, 8.9 mmg.; and of loosely bound biotin, 2.0 mmg. Per 100 Gm. of fresh weight the average content was: total thiamine, 47 mmg.; free thiamine 15 mmg.; total riboflavin, 151 mg.; free riboflavin, 54 mmg.; niacin, 1.99 mg.; pantothenic acid, 279 mmg.; firmly bound biotin, 1.6 mmg.; and loosely bound biotin, 0.4 mmg.