Maria Antonia Zancanaro de Figueiredo

Oral erythroplakia and speckled leukoplakia: retrospective analysis of 13 cases

UNLABELLEDnErythroplakia and speckled leukoplakia are oral precancerous lesions that have a high potential for malignant transformation.nnnAIMnA retrospective analysis was conducted to investigate the clinicopathologic features of 13 cases of oral erythroplakia and speckled leukoplakia in patients who were seen at a center specialized in stomatology and Histopathological diagnosis of oral diseases.nnnMATERIALS AND METHODSnAll cases diagnosed with erythroplakia and speckled leukoplakia between 1978 and 2006 were retrieved from the service archives.nnnRESULTSnThe lesions exhibited a predilection for males with a female-to-male ratio of 1:3.3. Mean age was 57 years old and soft palate was the site affected in 77% of the cases. Pain symptoms were reported by 61.5% of the patients and association with risk factors such as smoking and excessive alcohol intake was seen in 100% and in 46% of the cases, respectively. The lesions showed epithelial dysplasia, where more than 50% were diagnosed as in situ or invasive carcinoma.nnnCONCLUSIONSnDespite low prevalence, oral homogeneous erythroplakia and speckled leukoplakia show Histopathological alterations vary from epithelial dysplasia to invasive carcinoma. These lesions must be included among those oral lesions with the highest potential for malignant tranformation.

Eritroplasia e leucoeritroplasia oral: análise retrospectiva de 13 casos

Eritroplasia e leucoeritroplasia sao lesoes orais cancerizaveis com elevado potencial de transformacao maligna. OBJETIVOS: Neste estudo retrospectivo foram analisadas as caracteristicas clinico-patologicas de 13 casos de eritroplasias e leucoeritroplasias orais de pacientes atendidos em um Servico especializado em Estomatologia e diagnostico histopatologico. MATERIAL E METODO: Foram revisados os registros de biopsia de pacientes atendidos entre os anos de 1978 e 2006. Foram registradas e caracteristicas clinicas e histopatologicas das lesoes, bem como sexo, idade dos pacientes e associacao com fatores de risco. RESULTADOS: As lesoes exibiram predilecao por pacientes do sexo masculino na proporcao de 1:3.3. A media etaria dos individuos foi de 57 anos e o palato mole foi o sitio envolvido em 77% dos casos. Sintomatologia dolorosa foi relatada por 61,5% dos pacientes e associacao com tabagismo e etilismo foi observada em 100% e em 46% dos casos, respectivamente. As lesoes analisadas exibiam displasia epitelial e mais de 50% foram diagnosticadas como carcinoma in situ ou carcinoma invasivo. CONCLUSOES: Apesar de apresentarem baixa prevalencia, as eritroplasias homogeneas e as leucoplasias salpicadas exibem alteracoes epiteliais que vao de displasia epitelial a carcinoma invasivo, o que justifica sua inclusao entre as lesoes bucais com maior potencial de malignizacao.

Uso de goma de mascar: um método eficiente e seguro.para controlar a xerostomia?

The authors do a literature review napproaching basic concepts on nxerostomia and try to investigate the neffectiveness and safety of salivary nstimulation by chewing gum. nEvidences indicate that, up to now, nthere are no scientific basis to prove nthe persistent effect of this method nand that more clinical studies are nneeded to clarify the issue. nKey words: xerostomia, nchewing gum, salivary flow, safety.