Maria Balle

Relationships between negative affectivity, emotion regulation, anxiety, and depressive symptoms in adolescents as examined through structural equation modeling

The relationship between negative affectivity (NA) and emotion regulation (ER) in determining anxiety and depressive symptomatology was examined in a large (n=1441) sample of adolescents (12-17 years old). Two models, diverging only as to inclusion or exclusion of a path from NA to negative ER, were analyzed through structural equation modeling; the goal was to explore the mediational or non-mediational role of ER in determining anxiety symptoms. The models yielded similar adequate fit to data, indicating that both NA and negative ER contribute to anxiety symptoms which, in turn, significantly determine depressive symptomatology. The mediational model better captures the relationships revealed in the data, with NA determining negative ER to a great extent. Additionally, most individuals scoring highly in NA also tend to score highly in negative ER, indicating that adolescents with heightened NA are prone to a dysfunctional style of ER.

Efficacy of a brief school-based program for selective prevention of childhood anxiety

Abstract Anxiety sensitivity (AS) is recognized as an early risk factor for the development of anxiety disorders. This study evaluates whether a brief school-based selective prevention program reduces AS and anxious and depressive symptoms in children and youth. Participants scoring high in AS but without any current psychopathological disorder were selected from a sample of 613 individuals (61% female, 11–17 years old) and randomly assigned to the prevention program (n=47) or to a waiting-list control (WLC) (n=45) group. A normal control (NC) group (n=53) was also included. After treatment, a significant decrease in AS and in anxiety and depressive symptoms were observed in both prevention and WLC groups. Differences between experimental conditions only emerged, partially, at six-month follow-up (FU) with the prevention group (PG) exhibiting significantly lower AS (p<.05), and equalling NCs. Although the magnitude of change in the PG is comparable to that reported in previous studies with longer and more complex prevention programs, a parallel reduction in the WLCs suggests that the observed decrease in the short term could be mostly time-linked. Despite this, our results encourage research into brief preventive interventions at an individual level.

Attentional control, attentional network functioning, and emotion regulation styles

Attentional network functioning in emotionally neutral conditions and self-reported attentional control (AC) were analysed as predictors of the tendency to engage in dysfunctional emotion regulation strategies. Diminished attentional orienting predicted an increased tendency to engage in brooding rumination, and enhanced alertness predicted a greater chance of suppression, beyond trait anxiety and self-reported AC, which were not predictive of either rumination or suppression. This is the first study to show that some forms of dysfunctional emotion regulation are related to the attentional network functioning in emotionally neutral conditions. Results are discussed in relation to regulatory temperament and anxiety-related attentional biases literature.

Ecological assessment of heart rate complexity: Differences between high- and low-anxious adolescents.

Nonlinear measures can capture the complex structure of the heart beating, and recordings taken while the individual performs daily activities may help to understand the cardiac systems output in natural conditions. As healthy systems are characterized by having highly complex outputs, we hypothesized that the cardiac output from high anxious adolescents should be less complex than the output from their low anxious counterparts. In this study ECG was recorded for two hours in 50 adolescents while they performed regular school activities. Fractal dimension (FD), scaling exponents and multiscale entropy were calculated on the interbeat intervals time series. Both FD and entropy were significantly lower in the high-anxious group than the low-anxious group. These results suggest different heart-related regulation in adolescents who suffered from high anxious symptomatology.

Distinguishing youths at risk for anxiety disorders from self-reported BIS sensitivity and its psychophysiological concomitants

The aim of the study was to explore the psychophysiological concomitants of self-reported behavioral inhibition system (BIS) sensitivity in adolescents (12 to 17 years old) supposed to be at risk for anxiety disorders. Twenty participants with high scores in self-reported BIS sensitivity (at-risk group) were matched in age and sex to 20 participants scoring in the normal range in BIS sensitivity (control group). Negative affect, negative emotion regulation style, and anxiety symptomatology were assessed by means of self-reported measures. Cardiac and electrodermal response signals were recorded during baseline, paced breathing, exposure to an attentional task with response cost and fear-relevant slides conditions. The at-risk group exhibited higher scores on measures of negative affect, negative emotion regulation style, and anxiety symptomatology than their control counterparts. After controlling for negative styles of emotion regulation, groups did not differ in skin conductance reactivity during the attentional task with response cost, but participants at risk exhibited more nonspecific skin conductance responses than the control group during baseline recording. Regarding the cardiac concomitants, participants at risk presented lower vagal tone at resting conditions as compared to participants in the control group. Additionally, at-risk participants exhibited lower flexibility across experimental conditions in heart rate and cardiac sample entropy measures than participants in the control group. These findings add knowledge on psychophysiological concomitants of BIS sensitivity and are discussed in light of associations between temperament and development of anxiety disorders in youth. They show how psychophysiological patterns observed in resting conditions could be useful endophenotypes to reliably detect individuals at risk before the disorder onset.

Resting parietal EEG asymmetry and cardiac vagal tone predict attentional control.

The present study explores both resting cortical EEG asymmetry and vagally-mediated heart rate variability (HRV), as an index for vagal tone, as physiological correlates of self-reported attentional control in a sample of 53 healthy young adults. Regression analyses indicate that higher vagally-mediated HRV and lower right-sided parietal activity in the β2 frequency range (20-30Hz) are significant predictors of larger attentional control. Results are in line with some of the basic features of the neurovisceral integration model and stress the role of parietal areas in attentional control capabilities, thus aiming to consider attentional control as a trait-like disposition.

Complexity and nonlinear biomarkers in emotional disorders: A meta-analytic study.

This meta-analysis aimed at gathering and summarising the findings on nonlinear biomarkers in the field of emotional disorders under the hypothesis that diseased systems show lowered complexity and hence less flexibility to adjust daily contexts. Scientific manuscripts from 1970 to 2014 were reviewed, 58 articles were analysed, and independent meta-analyses on anxiety disorders, bipolar disorders, and depressive disorders were conducted. Results revealed that anxious patients exhibited lower complexity than controls (p<0.05) despite panic patients showed more irregular respiratory activity. Inconclusive results were found for bipolar patients but pointed to higher randomness when suffering manic episodes. Finally, depressed patients showed a loss of complexity in the cardiac system and a loss of orderliness (despite a higher complexity) in brain and stress-related hormonal systems. As a conclusion, our findings highlight that either a loss of complexity or a loss of ordered complexity characterise the physiological systems of patients with emotional disorders. Several considerations for complexity, its related measurements, and suggestions for further research are discussed.

Spontaneous EEG activity and spontaneous emotion regulation

Variability in both frontal and parietal spontaneous EEG activity, using α and β band power and θ/β and δ/β ratios, was explored in a sample of 96 healthy volunteers as a potential correlate of individual differences in spontaneous emotion regulation (SER). Following a baseline EEG recording, participants were asked to continuously rate their discomfort while looking at affective pictures, as well as for a period of time after exposure. Greater spontaneous β band power in parietal locations, lower frontal and parietal δ/β ratios, and lower parietal θ/β ratio were associated with lower ratings of discomfort after the offset of unpleasant pictures. Moreover, lower parietal δ/β ratio was also related to less time needed to recover from discomfort after exposure to aversive pictures, while only a greater frontal and parietal α band power appeared to be associated with faster recovery from discomfort induced by normative-neutral pictures. However, parietal δ/β ratio was the only predictor of both minimum discomfort ratings and time needed to downregulate following exposure to unpleasant pictures, and frontal α band power the only spontaneous EEG index that predicted variability in spontaneous down-regulation after the exposure to normative-neutral pictures. Results are discussed focusing on the utility of diverse spontaneous EEG measures in several cortical regions when capturing trait-like individual differences in emotion regulation capabilities and processes.

Spontaneous emotion regulation and attentional control.

The current study aimed to explore whether self-reported attentional control (AC) and the attentional network functioning would predict spontaneous emotion downregulation after emotional induction. A total of 117 healthy volunteers were asked to continuously rate their discomfort while looking at affective pictures, as well as for a period of time after exposure. After controlling for trait anxiety, higher self-reported AC significantly predicted a greater spontaneous emotional downregulation after exposure to aversive pictures. Both higher self-reported AC and lower executive control network functioning (i.e., greater interference) predicted a faster spontaneous emotional downregulation after exposure to affectively neutral pictures. Results are discussed focusing on the relationship between AC and emotion regulation difficulties. (PsycINFO Database Record

Self-focused cognitive emotion regulation style as associated with widespread diminished EEG fractal dimension.

The cognitive regulation of emotions is important for human adaptation. Self-focused emotion regulation (ER) strategies have been linked to the development and persistence of anxiety and depression. A vast array of research has provided valuable knowledge about the neural correlates of the use of specific self-focused ER strategies; however, the resting neural correlates of cognitive ER styles, which reflect an individuals disposition to engage in different forms of ER in order to manage distress, are largely unknown. In this study, associations between theoretically negative ER style (self-focused or not) and the complexity (fractal dimension, FD) of the resting EEG at frontal, central, parietal, and occipital regions were investigated in 58 healthy volunteers. The Cognitive Emotion Regulation Questionnaire was used as the self-report measure of ER style. Results showed that a diminished FD over the scalp significantly correlated with self-focused ER style scores, even after controlling for negative affect, which has been also considered to influence the use of ER strategies. The lower the EEG FD, the higher were the self-focused ER style scores. Correlational analyses of specific self-focused ER strategies showed that self-blaming and rumination were negatively associated with diminished FD of the EEG, but catastrophizing and blaming others were not. No significant correlations were found for ER strategies more focused on situation or others. Results are discussed within the self-organized criticality theory of brain dynamics: The diminished FD of the EEG may reflect a disposition to engage in self-focused ER strategies as people prone to ruminate and self-blame show a less complex resting EEG activity, which may make it more difficult for them to exit their negative emotional state.