María Dolores González

Bovine glycomacropeptide ameliorates experimental rat ileitis by mechanisms involving downregulation of interleukin 17.

Bovine glycomacropeptide (BGMP) is an inexpensive, non‐toxic milk peptide with anti‐inflammatory effects in rat experimental colitis but its mechanism of action is unclear. It is also unknown whether BGMP can ameliorate inflammation in proximal regions of the intestine. Our aim was therefore two‐fold: first, to determine the anti‐inflammatory activity of BGMP in the ileum; second, to characterise its mechanism of action.

Microwave-assisted synthesis of sulfonic acid-functionalized microporous materials for the catalytic etherification of glycerol with isobutene

Commercial Beta, ZSM-5 and mordenite zeolites and commercial montmorillonite K-10 were successfully sulfonated by a one-step simple method using microwaves. Different amounts of the sulfonating agent were required to maximize the incorporation of sulfonic groups for each structure. This has been related to the different dealumination degree suffered by the starting samples during sulfonation together with the different accessibility of the silanols to the sulfonic groups depending on the arrangement and size of their pores. All optimised sulfonated catalysts showed total conversion and very high selectivity (79–91%) to h-GTBE (glycerol di- and tri-ethers), in spite of their microporosity, due to the incorporation of the sulfonic groups that led to a higher number and strength of Bronsted acid sites. Pore size and arrangement together with the external surface area of the catalysts affected the accessibility of the acid sites to the reactants, explaining the evolution of the catalytic results with time for each structure.