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Featured researches published by Maria Nunes.


British Journal of Ophthalmology | 2002

Prevalence of visual impairment in people aged 75 years and older in Britain: results from the MRC trial of assessment and management of older people in the community

Jennifer R Evans; Astrid E. Fletcher; Richard Wormald; E Siu-Woon Ng; Sue Stirling; Liam Smeeth; Elizabeth Breeze; Christopher J. Bulpitt; Maria Nunes; Dee Jones; Alistair Tulloch

Aims: To measure the prevalence of visual impairment in a large representative sample of people aged 75 years and over participating in the MRC trial of assessment and management of older people in the community. Methods: 53 practices in the MRC general practice research framework. Data were obtained from 14 600 participants aged 75 years and older. Prevalence of visual impairment overall (binocular visual acuity <6/18) which was categorised separately into low vision (binocular visual acuity <6/18–3/60) or blindness (binocular visual acuity of <3/60). The prevalence of binocular acuity <6/12 was presented for comparison with other studies. Visual acuity was measured using Glasgow acuity charts; glasses, if worn, were not removed. Results: Visual acuity was available for 14 600 people out of 21 241 invited (69%). Among people with visual acuity data, 12.4% overall (1803) were visually impaired (95% confidence intervals 10.8% to 13.9%); 1501 (10.3%) were categorised as having low vision (8.7% to 11.8%), and 302 (2.1%) were blind (1.8% to 2.4%). At ages 75–79, 6.2% of the cohort were visually impaired (5.1% to 7.3%) with 36.9% at age 90+ (32.5% to 41.3%). At ages 75–79, 0.6% (0.4% to 0.8%) of the study population were blind, with 6.9% (4.8% to 9.0%) at age 90+. In multivariate regression, controlling for age, women had significant excess risk of visual impairment (odds ratio 1.43, 95% confidence interval 1.29 to 1.58). Overall, 19.9% of study participants had a binocular acuity of less than 6/12 (17.8% to 22.0%). Conclusion: The results from this large study show that visual impairment is common in the older population and that this risk increases rapidly with advancing age, especially for women. A relatively conservative measure of visual impairment was used. If visual impairment had been defined as visual acuity of <6/12 (American definition of visual impairment), the age specific prevalence estimates would have increased by 60%.


The Lancet | 2002

Reduced hearing, ownership, and use of hearing aids in elderly people in the UK--the MRC Trial of the Assessment and Management of Older People in the Community: a cross-sectional survey.

Liam Smeeth; Astrid E. Fletcher; Edmond Siu-Woon Ng; Sue Stirling; Maria Nunes; Elizabeth Breeze; Christopher J. Bulpitt; Dee Jones; Alistair Tulloch

BACKGROUND Reduced hearing in elderly people is important because it is disabling and potentially treatable. We aimed to assess the prevalence of reduced hearing in elderly people and levels of ownership of hearing aids and use. METHODS We have done a cross-sectional survey of people aged at least 75 years in 106 family practices in the UK. We obtained self-reported data on hearing difficulties for 32,656 people and gave 14,877 a whispered voice test (response rate 78%). FINDINGS 2537 (8%) of 32,656 participants reported a lot of difficulty hearing and 13,630 (42%) a little or a lot of difficulty. 3795 (26%) of 14877 participants who completed the whispered voice test (95% CI 23-29) failed the test, the proportion rising sharply with age. Following wax removal, 343 passed a retest, leaving 3452 (23%, 20-26) who failed the test, even after wax removal if present. 998 (46%) of 2180 people wearing a hearing aid at the time of testing failed the whispered voice test. More than half the people who failed the test did not own a hearing aid. 2200 (60%) of 3846 people who owned a hearing aid said they used it regularly. Level of use was strongly related to perceived benefit. INTERPRETATION Reduced hearing is common and provision of hearing aids inadequate in elderly people. Many people who own a hearing aid do not use it regularly, and even when wearing their aid many still have socially disabling levels of hearing loss. A major source of morbidity in elderly people could be alleviated by improvements in detection and management of reduced hearing.


BMJ | 2001

Randomised comparison of three methods of administering a screening questionnaire to elderly people: findings from the MRC trial of the assessment and management of older people in the community

Liam Smeeth; Astrid E. Fletcher; Susan Stirling; Maria Nunes; Elizabeth Breeze; Edmond S. W. Ng; Christopher J. Bulpitt; Dee Jones

Abstract Objective: To compare three different methods of administering a brief screening questionnaire to elderly people: post, interview by lay interviewer, and interview by nurse. Design: Randomised comparison of methods within a cluster randomised trial. Setting: 106 general practices in the United Kingdom. Participants: 32 990 people aged 75 years or over registered with participating practices. Main outcome measures: Response rates, proportion of missing values, prevalence of self reported morbidity, and sensitivity and specificity of self reported measures by method of administration of questionnaire for four domains. Results: The response rate was higher for the postal questionnaire than for the two interview methods combined (83.5% v 74.9%; difference 8.5%, 95% confidence interval 4.4% to 12.7%, P<0.001). The proportion of missing or invalid responses was low overall (mean 2.1%) but was greater for the postal method than for the interview methods combined (4.1% v 0.9%; difference 3.2%, 2.7% to 3.6%, P<0.001). With a few exceptions, levels of self reported morbidity were lower in the interview groups, particularly for interviews by nurses. The sensitivity of the self reported measures was lower in the nurse interview group for three out of four domains, but 95% confidence intervals for the estimates overlapped. Specificity of the self reported measures varied little by method of administration. Conclusions: Postal questionnaires were associated with higher response rates but also higher proportions of missing values than were interview methods. Lower estimates of self reported morbidity were obtained with the nurse interview method and to a lesser extent with the lay interview method than with postal questionnaires. What is already known on this topic The optimum method of administering a brief multidimensional screening assessment to elderly people is not known What this study adds Postal questionnaires produce a higher response rate than interviews by nurses or lay interviewers but also higher proportions of missing data Interview by nurses and to a lesser degree by lay interviewers is associated with lower levels of self reported morbidity than are postal questionnaires


Journal of Cardiovascular Risk | 2001

Quality of life in the elderly hypertensive.

Maria Nunes

The approach to the treatment of hypertension in the elderly hypertensive should take into account the effects of the different antihypertensive drugs on the quality of life, especially in the elderly where a small reduction in health status could have an impact on their independence.


Journal of Hypertension | 2003

Results of the pilot study for the Hypertension in the Very Elderly Trial.

Christopher J. Bulpitt; Nigel S. Beckett; Jonathan Cooke; Dan Dumitrascu; Blas Gil-Extremera; Choudomir Nachev; Maria Nunes; Ruth Peters; Jan A. Staessen; Lutgarde Thijs


The Lancet | 2004

Population-based multidimensional assessment of older people in UK general practice: a cluster-randomised factorial trial

Astrid E. Fletcher; Gill M Price; Edmond S. W. Ng; Susan Stirling; Christopher J. Bulpitt; Elizabeth Breeze; Maria Nunes; Dee Jones; Amina M Latif; Nicola M Fasey; Madge R Vickers; Alistair Tulloch


Age and Ageing | 2005

Prevalence of cognitive impairment: results from the MRC trial of assessment and management of older people in the community

Greta Rait; Astrid E. Fletcher; Liam Smeeth; Carol Brayne; Susan Stirling; Maria Nunes; Elizabeth Breeze; Edmond Siu-Woon Ng; Christopher J. Bulpitt; Dee Jones; Alistair Tulloch


International Journal of Geriatric Psychiatry | 2003

Factors associated with depression in a representative sample of 14 217 people aged 75 and over in the United Kingdom: results from the MRC trial of assessment and management of older people in the community.

David P. J. Osborn; Astrid E. Fletcher; Liam Smeeth; Susan Stirling; Christopher J. Bulpitt; Elizabeth Breeze; Edmond S. W. Ng; Maria Nunes; Dee Jones; Alistair Tulloch


Clinical Nutrition | 2004

Does additional feeding support provided by health care assistants improve nutritional status and outcome in acutely ill older in-patients?--a randomised control trial.

Christopher J. Bulpitt; Maria Nunes; Ruth Peters; Jonathon Cooke; C G Nicholl; Gary Frost


International Journal of Geriatric Psychiatry | 2002

Geriatric Depression Scale Scores in a representative sample of 14 545 people aged 75 and over in the United Kingdom: results from the MRC Trial of Assessment and Management of Older People in the Community

David P. J. Osborn; Astrid E. Fletcher; Liam Smeeth; Susan Stirling; Maria Nunes; Elizabeth Breeze; Edmond Siu-Woon; Christopher J. Bulpitt; Dee Jones; Alistair Tulloch

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Ruth Peters

Imperial College London

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