Maria Yu

Infectious post-LASIK crystalline keratopathy caused by nontuberculous mycobacteria.

Purpose. To report three cases of infectious crystalline keratopathy caused by non-tuberculous mycobacteria after LASIK surgery. Methods. Interventional case reports and literature review. Results. Infectious keratitis with clinical features of crystalline keratopathy after LASIK is described. Culture revealed Mycobacterium chelonae from the corneal scrapings of the three patients, all of whom underwent medical and surgical (debridement) treatment. Conclusions. Mycobacteria may cause infectious crystalline keratopathy after LASIK. The presence of crystalline keratopathy in patients that underwent LASIK must be considered an indicator of nontuberculous mycobacteria infection. Microbiologic work-up of a corneal specimen is required for the institution of appropriate therapy.

Exophiala jeanselmei causing late endophthalmitis after cataract surgery

PURPOSE To report two cases of late endophthalmitis caused by Exophiala jeanselmei after cataract surgery. METHODS Case reports, including clinical evaluation, direct examination, and culture of the aqueous humor. RESULTS In each case, samples from the anterior chamber had positive growth of yeasts with toruloid hyphae and pseudohyphae. Intravitreal and anterior chamber amphotericin B were used in both cases. Apparent clinical resolution was achieved, but after 3 months in one case and 6 months in the other the infection recurred more aggressively, with severe endophthalmitis leading to ocular atrophy. CONCLUSION E. jeanselmei causes a severe intraocular infection and isolation, and identification of the agent ensures proper diagnosis and treatment. After clinical resolution of the infection, careful and long-term follow-up is recommended to promptly detect relapse and immediately reintroduce treatment.