Mariano Martínez Vázquez

Effect of crude extracts of Erythrina americana Mill. on aggressive behavior in rats.

Three alkaloid fractions were obtained from seeds of Erythrina americana: free alkaloids in hexane, free alkaloids in methanol and liberated alkaloids. The pharmacological evaluation of these fractions on rats showed that, administered in a dose of 3 mg/kg, the three fractions diminished the aggressive behavior. This is comparable when diazepam is used as a control. An interaction between the cholinergic and GABAergic system could be suggested.

Three flavonoids from Ageratum tomentosum var. bracteatum

Abstract The three new compounds, 5,6,7,8,3′,4′,5′-heptamethoxyflavanone, 2′,4′-dihydroxy-5,6,7,8,5′-pentamethoxyflavone and 7-hydroxy-5,6,8,5′-tetramethoxy-3′,4′-methylenedioxyflavone were isolated from the aerial parts of Ageratum tomentosum var. bracteatum , together with five known flavones and one known flavanone. The structures of the new compounds were elucidated by spectral analysis.