Marie Aleth Lacaille-Dubois
University of Burgundy
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Publication
Featured researches published by Marie Aleth Lacaille-Dubois.
Phytochemistry | 2009
Luc Meva’a Mbaze; Jean Alexandre Lado; Jean Duplex Wansi; Tze Chieh Shiao; David Dako Chiozem; Muhammad Ahmed Mesaik; Muhammad Iqbal Choudhary; Marie Aleth Lacaille-Dubois; Jean Wandji; René Roy; Norbert Sewald
Two amides, heitziamide A and heitziamide B and two phenylethanoids, heitziethanoid A and heitziethanoid B together with thirteen known compounds were isolated from F. heitzii (Letouzey). The structures of all compounds were established by spectroscopic analysis. Nine compounds were evaluated for oxidative burst inhibitory activity in a chemoluminescence assay and for cytotoxicity against PC-3 prostate cancer cells. All compounds exhibited a clear suppressive effect on phagocytosis response upon activation with serum opsonized zymosan at the range of IC(50)=2.0-6.5 microM, but no cytotoxic effect was observed (IC(50)>100 microM).
Phytochemistry | 2013
Gaoussou Timité; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Chiaki Tanaka; Jean François Mirjolet; Olivier Duchamp; Marie Aleth Lacaille-Dubois
A phytochemical analysis of the whole plant of Allium schoenoprasum, has led to the isolation of four spirostane-type glycosides (1-4), and four known steroidal saponins. Their structures were elucidated mainly by 2D NMR spectroscopic analysis and mass spectrometry as (20S,25S)-spirost-5-en-3β,12β,21-triol 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (1), (20S,25S)-spirost-5-en-3β,11α,21-triol 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (2), laxogenin 3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→4)]-β-D-glucopyranoside (3), and (25R)-5α-spirostan-3β,11α-diol 3-O-β-D-glucopyranosyl-(1→3)-[β-D-glucopyranosyl-(1→4)]-β-D-galactopyranoside (4). Four of the isolated compounds were tested for cytotoxic activity against the HCT 116 and HT-29 human colon cancer cell lines.
Phytochemistry | 2014
Mahenina Jaovita Manase; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Chiaki Tanaka; Stéphanie Delemasure; Patrick Dutartre; Marie Aleth Lacaille-Dubois
Four triterpenoid saponins (1-4) were isolated from Polycarpaea corymbosa Lamk. var. eriantha Hochst along with the known apoanagallosaponin IV (5). Their structures were elucidated by spectroscopic data analysis. Among the compounds 1, 3-5 which were evaluated for their cytotoxicity against three tumor cell lines (SW480, DU145 and EMT6), compound 1 exhibited cytotoxicity with IC50 values ranging from 4.61 to 22.61 μM, which was greater than that of etoposide. Compound 2 was tested only against SW480 and a cardiomyoblast cell line (H9c2), and was inactive.
Phytochemistry | 2014
David Pertuit; Sibel Avunduk; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Chiaki Tanaka; Thomas Paululat; Stéphanie Delemasure; Patrick Dutartre; Marie Aleth Lacaille-Dubois
Two triterpenoid saponins with two known ones have been isolated from the roots of Gypsophila arrostii var. nebulosa, and two new ones from the roots of Gypsophila bicolor. Their structures were established by extensive NMR and mass spectroscopic techniques as 3-O-β-d-galactopyranosyl-(1→2)-[β-d-xylopyranosyl-(1→3)]-β-d-glucuronopyranosylquillaic acid 28-O-β-d-xylopyranosyl-(1→4)-[β-d-glucopyranosyl-(1→3)]-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-fucopyranosyl ester (1), 3-O-β-d-galactopyranosyl-(1→2)-[β-d-xylopyranosyl-(1→3)]-β-d-glucuronopyranosylgypsogenin 28-O-β-d-xylopyranosyl-(1→4)-[β-d-glucopyranosyl-(1→3)]-α-l-rhamnopyranosyl-(1→2)-[β-d-glucopyranosyl-(1→4)]-β-d-fucopyranosyl ester (2), 3-O-β-d-galactopyranosyl-(1→2)-[β-d-xylopyranosyl-(1→3)]-β-d-glucuronopyranosylgypsogenin 28-O-β-d-xylopyranosyl-(1→3)-β-d-xylopyranosyl-(1→4)-α-l-rhamnopyranosyl-(1→2)-[(4-O-acetyl)-β-d-quinovopyranosyl-(1→4)]-β-d-fucopyranosyl ester (3), gypsogenic acid 28-O-β-d-glucopyranosyl-(1→3)-{6-O-[3-hydroxy-3-methylglutaryl]-β-d-glucopyranosyl-(1→6)}-β-d-galactopyranosyl ester (4). Three compounds were evaluated against one human colon cancer cell line SW480 and one rat cardiomyoblast cell line H9c2.
Magnetic Resonance in Chemistry | 2011
Aymen Jabrane; Hichem Ben Jannet; Tomofumi Miyamoto; Chiaki Tanaka; Jean François Mirjolet; Olivier Duchamp; Fethia Harzallah-Skhiri; Marie Aleth Lacaille-Dubois
From the roots of Atriplex glauca L. var. ifiniensis (Caball) Maire (syn. of Atriplex parvifolia Lowe var. genuina Maire), three new saikosaponins designated as glaucasides A–C (1–3) were isolated together with the known 3‐O‐
Nutrition Research | 2010
Sherazede Bouderbala; Josiane Prost; Marie Aleth Lacaille-Dubois; Malika Bouchenak
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Phytochemistry | 2015
Sinem Aslan Erdem; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Murat Kartal; Marie Aleth Lacaille-Dubois
‐D‐glucopyranosyl‐(1 → 2)‐
Phytochemistry | 2013
Alida Pérez Colmenares; Luis B. Rojas; Anne Claire Mitaine-Offer; Laurent Pouységu; Stéphane Quideau; Tomofumi Miyamoto; Chiaki Tanaka; Thomas Paululat; Alfredo Usubillaga; Marie Aleth Lacaille-Dubois
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Phytochemistry | 2016
Abdelmalek Rezgui; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Chiaki Tanaka; Stéphanie Delemasure; Patrick Dutartre; Marie Aleth Lacaille-Dubois
‐D‐galactopyranosyl‐saikogenin F (4). The structures of the new compounds were elucidated by extensive analysis of one‐dimensional and two‐dimensional NMR spectroscopy, FABMS, HR‐ESIMS and chemical evidence as 13
Fitoterapia | 2016
Karima Ounaissia; David Pertuit; Anne Claire Mitaine-Offer; Tomofumi Miyamoto; Chiaki Tanaka; Stéphanie Delemasure; Patrick Dutartre; Dalila Smati; Marie Aleth Lacaille-Dubois
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