Marie Baudyšová
Czechoslovak Academy of Sciences
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Featured researches published by Marie Baudyšová.
FEBS Letters | 1991
Josef Houštěk; Peter Tvrdík; Stanislav Pavelka; Marie Baudyšová
The mRNA levels of ATPase β, ATPase 6, cytochrome oxidase (COX) VIb and COX I subunits were found to be 2.4–13.8‐fold higher in brown adipose tissue (BAT) than in heart, skeletal muscle, brain and liver of mice. The comparison with tissue contents of ATPase and COX revealed that the selective, 5–11‐fold reduction of ATPase in BAT is not caused by decreased transcription of ATPase genes. Likewise, the ATPase β and COX VIb mRNA levels in cultured brown adipocytes were also not influenced by norepinephrine, which activated the expression of the UCP gene by two orders of magnitude. The results indicate that the biosynthesis of mitochondrial ATPase in BAT is post‐transcriptionally regulated.
Archive | 1992
Josef Houstek; Jan Kopecky; Stanislav Pavelka; Petr Tvrdík; Marie Baudyšová; Karel Vízek; Jana Hermanska; Dagmar Janíková
Biogenesis of two energy-converting and adenine nucleotide-binding proteins of brown adipose tissue mitochondria — the uncoupling protein (UCP) and ATP synthase (ATPase) has been investigated in situ and in cell cultures. Highly differentiated synthesis of these proteins was found to result from distinct regulatory events. Tissue-specific, heat-producing UCP is transcriptionally regulated by a cAMP-dependent and triiodothyronine-dependent mechanism which is operated through β3 adrenoreceptors and involves de-novo synthesis of intracellular iodothyronine 5′-deiodinase. UCP gene can be rapidly turned on and the rate of its expression can differ by several orders of magnitude. In contrast, the synthesis of ATPase which is highly depressed in brown adipose tissue appears to be posttranscriptionally controled and does not exhibit apparent sensitivity to catecholamines.
Advances in Experimental Medicine and Biology | 1975
E. Holečková; Marie Baudyšová
In adult rats acclimated to 5 degrees C, the kidney weight increases with the length of the exposure. Kidney cells of younger rats survive explantation better than the cells of control rats of the same age. Kidney cells of older rats after cold acclimation and after unilateral nephrectomy have a lower vitality in vitro than corresponding control cells. Unilateral nephrectomy performed in rats aged 3 and 6 months, exposed previously to low temperature, leads to a better survival of explanted kidney cells than nephrectomy or cold only. Old rats do not survive exposure to 5 degrees C for more than 18 hr.
Journal of Biological Chemistry | 1990
Jan Kopecký; Marie Baudyšová; F Zanotti; Dagmar Janíková; Stanislav Pavelka; J Houstĕk
Biochimica et Biophysica Acta | 1990
Josef Houštěk; Jan Kopecký; Marie Baudyšová; Dagmar Janíková; Stanislav Pavelka; Petr Klement
FEBS Letters | 1990
Josef Houšteˇk; Stanislav Pavelka; Marie Baudyšová; Jan Kopecký
Biochemical Journal [IF=3.659 (1992); SCI #cit.] | 1993
Stanislav Pavelka; Jana Heřmanská; Marie Baudyšová; Josef Houštěk
Archive | 1992
Josef Houštěk; Petr Tvrdík; Štefan Kužela; Stanislav Pavelka; Marie Baudyšová; Jan Kopecký
Archive | 1991
Stanislav Pavelka; Marie Baudyšová; Jan Kopecký; Josef Houštěk
Journal of Cellular Biochemistry [IF=2.778 (1990)] | 1991
Jan Kopecký; Marie Baudyšová; Stanislav Pavelka; Francesco Zanotti; Dagmar Janíková; Josef Houštěk