Marija Semnic

Cognitive impairment in multiple system atrophy: a position statement by the Neuropsychology Task Force of the MDS Multiple System Atrophy (MODIMSA) study group.

Consensus diagnostic criteria for multiple system atrophy consider dementia as a nonsupporting feature, despite emerging evidence demonstrating that cognitive impairments are an integral part of the disease. Cognitive disturbances in multiple system atrophy occur across a wide spectrum from mild single domain deficits to impairments in multiple domains and even to frank dementia in some cases. Frontal‐executive dysfunction is the most common presentation, while memory and visuospatial functions also may be impaired. Imaging and neuropathological findings support the concept that cognitive impairments in MSA originate from striatofrontal deafferentation, with additional contributions from intrinsic cortical degeneration and cerebellar pathology. Based on a comprehensive evidence‐based review, the authors propose future avenues of research that ultimately may lead to diagnostic criteria for cognitive impairment and dementia associated with multiple system atrophy.

Segmental cavernous carotid ectasia in a patient with cluster-like headache

INTRODUCTION Cluster headache (CH) is a primary headache with severe, unilateral periorbital or temporal pain lasting 15-180 min, accompanied with various cranial autonomic features. A diagnosis of cluster-like headache can be made whenever underlying cause of CLH is present. METHODS AND RESULTS We report a case where an ectatic cavernous segment of the internal carotid artery triggered CHL, most probably due to compression of the ophthalmic nerve within cavernous sinus. The pathological substrate of a vessel ectasia is degeneration of the tunica intima as a consequence of atherosclerosis and hypertension. On the other hand, cavernous sinus is unique space where parasympathetic, sympathetic and nociceptive fibers are in intimate relationship which is of great importance for understanding of CH pathophysiology. CONCLUSION Magnetic resonance imaging and MR angiography are mandatory imaging tools used for precise localization of pathological changes in the cavernous sinus, especially in the group of secondary headaches attributed to vascular disorders.

DIFFERENCES BETWEEN MULTI-INFARCT DEMENTIA AND SMALL-VESSEL DISEASE DEMENTIA IN ATTENTION AND WORKING MEMORY DEFICITS

P3-268 DIFFERENCES BETWEENMULTI-INFARCT DEMENTIA AND SMALL-VESSEL DISEASE DEMENTIA IN ATTENTION ANDWORKING MEMORY DEFICITS Marija D. Semnic, Robert R. Semnic, Vojislava V. Bugarski Ignjatovic, Tijana Stankov, Sanela B. Popovic, Dusko B. Kozic, Faculty of Medicine University of Novi Sad, Novi Sad, Serbia; Neuroradiology Department, Academical Hospital, University of Uppsala, Uppsala, Sweden; Faculty of Medicine University of Novi Sad, Novi Sad, Serbia. Contact e-mail: memoryns@gmail.com

Isolated Inflammatory Arthritis of the Atlantooccipital Joint Confused with Migraine

Magnetic resonance imaging (MRI) was performed in a 52-year-old woman with a several-year history of pharmacologically resistant, migraine-like, left hemicranial pain, lasting 48–72 h, accompanied with left eye “tunnel vision”. The presence of synovial effusion (Figure 1A and 1B) and associated dilated vein without erosions of the joint facets and cartilage (Figure 1C) were revealed on precontrast and postcontrast MRI, consistent with inflammatory arthritis …

Nonspecific perichondritis of the lumbar spine.

A teenage girl with soft tissue inflammation involving the L2‐S1 region of the lumbar region is reported. Magnetic resonance (MR) imaging revealed high‐signal lesions on T2‐weighted images in association with contrast enhancement. Histology revealed nonspecific perichondritis with mononuclear inflammatory infiltration of the perichondrium and connective tissue. Six months after treatment, MR imaging was normal. No similar case of perichondritis with involvement of the lumbar region could be found in the current literature.