Marina Belaya
Russian Academy of Sciences
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Featured researches published by Marina Belaya.
Langmuir | 2013
Victor Levadny; Taka-aki Tsuboi; Marina Belaya; Masahito Yamazaki
We investigated the effects of tension induced by micropipet aspiration on giant unilamellar vesicles (GUVs) composed of dioleoylphosphatidylglycerol (DOPG) and dioleoylphosphatidylcholine (DOPC). We analyzed the time course of the fraction of intact GUVs among all of the GUVs under constant tension σ and obtained the rate constants of pore formation kp(σ). To determine kp, we developed an approach using the mean first passage time. The fitting of the theoretical curves of kp versus σ to the experimental data determined the line tension of a prepore, Γ. The value of Γ of a DOPG/DOPC bilayer was smaller than that of a DOPC bilayer.
Biochimica et Biophysica Acta | 1998
Victor Levadny; Vicente M. Aguilella; Marina Belaya
We have considered the access resistance (AR) of a single conducting channel placed in a membrane bathed by an electrolyte. The classical expression for AR is due to Hall, who modeled the electrolyte as an ohmic conducting homogeneous medium. This approach is discussed in the present paper and it is shown that it is not valid in all cases, but depends on the ion concentration in solution and the ratio between solution and channel resistivities. To get a new expression for AR, we have combined the use of one-dimensional Nernst-Planck and Poisson (NPP) equations for the mouth of the channel and three-dimensional NPP equations for the outside solution. The influence of ion gradients and the channel itself on AR tums out to be considerable in diluted solutions (and also in the case of small channels in any solution). This influence is weaker in concentrated solutions, for which AR is well described by Halls expression.
Journal of Controlled Release | 1997
Vicente M. Aguilella; Marina Belaya; Victor Levadny
Some previous streaming potential and EMF measurements on human stratum corneum in vitro (J. Control. Release 32 (1994) 249) are explained in terms of a simple physical model based on the intercellular pathway for passive transport of small inorganic ions. These are assumed to diffuse across the hydrophilic region of the lipid lamellae. The polar region is assumed to have a finite thickness and to be partly penetrable by ions from solution. The hypothesis that the lipid ionized groups give rise to a point charge distribution together with a permanent dipole distribution helps to explain the observed, apparent change in skin selectivity with concentration.
Thin Solid Films | 1996
Vicente M. Aguilella; Marina Belaya; Victor Levadny
Abstract A membrane with soft permeable interfaces in an aqueous solution has been modelled by taking into account the spatial distribution of structural electric charges and dipoles in the interfaces. The model was developed with special stress on its application to biological membranes. The electric potential distribution and the ion transport across the membrane are studied and the important role of the interface thickness L on ion transport and membrane selectivity is shown. An interesting result is found for certain combinations of charge and dipole densities: a cation selective membrane may become anion selective when L changes. It is discussed how the results obtained can help to explain experimental results for membrane selectivity.
Langmuir | 1997
David A. Pink; Marina Belaya; Victor Levadny; Bonnie Quinn
Langmuir | 1994
Marina Belaya; Victor Levadny; David A. Pink
Physical Review E | 2015
Mohammad Abu Sayem Karal; Victor Levadnyy; Taka-aki Tsuboi; Marina Belaya; Masahito Yamazaki
Langmuir | 1994
Marina Belaya; Victor Levadny; David A. Pink
Physical Review E | 2004
Victor Levadny; Vicente M. Aguilella; Marcelo Aguilella-Arzo; Marina Belaya
Langmuir | 1998
Victor Levadny; Vicente M. Aguilella; Marina Belaya; Masahito Yamazaki