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Dive into the research topics where Marina Dias-Neto is active.

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Featured researches published by Marina Dias-Neto.


Nutrition and Cancer | 2010

Salt intake and risk of gastric intestinal metaplasia: systematic review and meta-analysis.

Marina Dias-Neto; Mariana Pintalhao; Mariana Ferreira; Nuno Lunet

The understanding of the association between salt intake and precancerous lesions may contribute to clarify the causal relation with gastric cancer. We systematically reviewed 17 articles addressing the association between dietary salt exposure and gastric intestinal metaplasia and conducted meta-analyses for quantitative synthesis (random effects model). Salt exposure was estimated assessing salted/salty food consumption, preference for salted/salty foods, use of table salt, or sodium urinary excretion. Heterogeneity was also large regarding food items evaluated, consumption categories, and data analysis. The combined odds ratio (OR) was 1.68 (95% confidence interval (CI) = 0.98–2.90; I2 = 55.4%) for the association between salted/salty meat and intestinal metaplasia (4 studies) and the OR was 1.53 (95% CI = 0.72–3.24; I2 = 76.8%) for salt preference. There was a positive, nonstatistically significant association between intestinal metaplasia and urinary sodium excretion. The heterogeneity of methodological options and results preclude quantitative synthesis or its proper interpretation, even if the available evidence may suggest a positive association between salt and intestinal metaplasia.


Vascular | 2017

Strategies to prevent TEVAR-related spinal cord ischemia:

Marina Dias-Neto; Pedro Videira Reis; Dalila Rolim; José Fernando Ramos; José Fernando Teixeira; Sérgio Sampaio

Spinal cord ischemia remains the Achilles’ heel of thoracic and thoracoabdominal diseases management. Great improvements in morbidity and mortality have been obtained with the endovascular approach TEVAR (Thoracic Endovascular Aortic Repair) but this devastating complication continues to severely affect the quality of life, even if the primary success of the procedure – dissection/aneurysm exclusion – has been achieved. Several strategies to deal with this complication have been published in the literature over the time. Knowledge and technology have been evolving from identification of the risk factors associated with spinal cord ischemia, including lessons learned from open surgery, and from developments in the collateral network concept for spinal cord perfusion. In this comprehensive review, the authors cover several topics from the traditional measures comprising haemodynamic control, cerebrospinal drainage and neuroprotective drugs, to the staged-procedures approach, the emerging MISACE (minimally invasive selective segmental artery coil-embolization) and innovative neurologic monitoring such as NIRS (near-infrared spectroscopy) of the collateral network.


Journal of Endovascular Therapy | 2018

Endovascular Treatment of Severely Calcified Femoropopliteal Lesions Using the “Pave-and-Crack” Technique: Technical Description and 12-Month Results:

Marina Dias-Neto; Manuela Matschuck; Yvonne Bausback; Ursula Banning-Eichenseher; Sabine Steiner; Daniela Branzan; Holger Staab; Ramon L. Varcoe; Dierk Scheinert; Andrej Schmidt

Purpose: To report midterm results of the “pave-and-crack” technique to facilitate safe and effective scaffolding of heavily calcified femoropopliteal lesions in preparation for delivery of a Supera interwoven stent. Methods: Data were collected retrospectively on 67 consecutive patients (mean age 71±8 years; 54 men) treated with this technique between November 2011 and February 2017 at a single center. A third (22/64, 34%) of the patients had critical limb ischemia (CLI). Most lesions were TASC D (52/67, 78%), and the majority were occlusions (61/66, 92%). The mean lesion length was 26.9±11.2 cm. Nearly two-thirds (40/64, 62%) had grade 4 calcification (Peripheral Arterial Calcium Scoring System). To prepare for Supera stenting, the most heavily calcified segments of the lesion were predilated aggressively to obliterate recoil. A Viabahn stent-graft was then implanted to “pave” the lesion and protect from vessel rupture as aggressive predilation continued until the calcified plaque was “cracked” before lining the entire lesion with a Supera stent. Patency and target lesion revascularization (TLR) rates were estimated using the Kaplan-Meier method. Results: Procedural success was achieved in 100% and technical success (residual stenosis <30%) in 98% (66/67). The mean cumulative stent lengths were 16±9 cm for the Viabahn and 23±12 cm for the Supera. Only 2 complications occurred (distal embolization and access-site pseudoaneurysm). Two CLI patients died within 30 days, and 3 patients (all claudicants) underwent a TLR. Patients were followed for a mean 19±18 months, during which another 2 CLI patients died and 1 patient had a major amputation. One-year primary and secondary patency estimates were 79% and 91%, respectively; freedom from TLR was 85%. Conclusion: Despite severe lesion calcification, patients experienced high technical success and a safe and durable therapy at midterm follow-up with the femoropopliteal “pave-and-crack” technique.


Nutrition and Cancer | 2010

Salt Intake and Type of Intestinal Metaplasia in Helicobacter Pylori-Infected Portuguese Men

Mariana Pintalhao; Marina Dias-Neto; Bárbara Peleteiro; Carla Lopes; Ceu Figueiredo; Leonor David; Nuno Lunet

The relation between salt intake and intestinal metaplasia (IM) types and the potential interaction with H. pylori virulence are poorly understood and may contribute to further understand gastric carcinogenesis. We quantified the association between dietary salt exposure and complete, incomplete, and mixed IM, taking into account the potential effect modification according to the virulence of H. pylori infecting strains. H. pylori-infected male volunteers (n = 233) underwent an upper digestive endoscopy and completed questionnaires comprising different measures of salt exposure (main food items/groups contributing to dietary salt intake, estimated dietary sodium intake, visual analogical scale for salt intake, preference for salty/salted foods). A histological diagnosis was assigned based on the most severe lesion observed. H. pylori virulence was assessed by characterizing vacA and cagA genes. Odds ratios were estimated through age- and education-adjusted logistic regression models. The risk of IM was not significantly increased in H. pylori infected subjects with higher levels of salt consumption. The lack of association was consistent across measures of salt exposure, categories of H. pylori virulence, and types of IM. In conclusion, in this H. pylori positive population, salt intake did not increase the risk of any IM type, regardless of the virulence of the infecting strains.


Vascular and Endovascular Surgery | 2018

Blunt Injury of the Innominate Artery: What Surprises to Expect? A Case Report:

Marina Dias-Neto; José Fernando Ramos; José Fernando Teixeira

Injuries of the supra-aortic trunk after blunt chest trauma are rare. This is a case report of a blunt traumatic lesion of the innominate artery (IA) origin that exhibited aortic arch involvement with a focus on imaging and treatment. A 41-year-old fisherman presented an IA injury secondary to a high-impact blunt chest trauma. Upon physical examination, vital signs were stable and upper extremity pulses were present. In addition to several bone fractures (costal ribs, clavicle, scapula, temporal, maxillary, and sphenoid), computed tomography angiography revealed dissection/pseudoaneurysm of the IA sparing the bifurcation. The patient underwent emergent angiography, which confirmed that the IA dissection was not ruptured, but it was unclear whether there was a pseudoaneurysm at the origin of the IA or aortic arch involvement. The patient was considered for open surgery. An ascending aorta-to-IA bypass was achieved by the off-pump beating heart approach. The IA stump was carefully observed, but oversewing was not possible due to the extension of the intimal-medial lesions into the artic arch. An on-pump intervention was then required for aortic angioplasty with a pericardial patch that was reinforced by Gel Seal. The postoperative course was uneventful. The patient was discharged without any complications. Conventional surgery provides good results and should remain in the armamentarium for the treatment of traumatic lesions at the IA origin, particularly if aortic arch involvement cannot be ruled out, to ensure a truly patient-tailored approach.


Pediatric Cardiology | 2015

Pathophysiology of Infantile Pulmonary Arterial Hypertension Induced by Monocrotaline

Marina Dias-Neto; Ana Luísa-Neves; Sónia Pinho; Nádia Gonçalves; Maria Aurora Mendes; Catarina Eloy; José Manuel Lopes; Daniel J. S. Gonçalves; Manuel J. Ferreira-Pinto; Adelino F. Leite-Moreira; Tiago Henriques-Coelho


Acta Médica Portuguesa | 2011

Neuregulin1/ErbB system: importance in the control of cardiovascular function

Luisa Lopes-Conceição; Marina Dias-Neto; Ana Patrícia Fontes-Sousa; P. Mendes-Ferreira; C. Maia-Rocha; Tiago Henriques-Coelho; Gilles W. De Keulenaer; Adelino Leite Moreira; Carmen Brás-Silva


European Journal of Vascular and Endovascular Surgery | 2018

High Density of Periaortic Adipose Tissue in Abdominal Aortic Aneurysm

Marina Dias-Neto; Jorn P. Meekel; Theodorus G. van Schaik; Jacqueline Hoozemans; Fábio Sousa-Nunes; Tiago Henriques-Coelho; Rutger J. Lely; Willem Wisselink; Jan D. Blankensteijn; Kak K. Yeung


Angiologia e Cirurgia Vascular | 2017

A transição epidemiológica no aneurisma da aorta abdominal

Marina Dias-Neto; José Fernando Ramos; Sérgio Sampaio; Alberto Freitas


The FASEB Journal | 2010

Exercise training has protective effects in monocrotaline induced pulmonary hypertension

Daniel Moreira-Gonçalves; Tiago Henriques-Coelho; Hélder Fonseca; Nádia Gonçalves; Manuel J. Ferreira-Pinto; Marina Dias-Neto; Francisco Vasques-Nóvoa; Adelino F. Leite-Moreira; José Alberto Duarte

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