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Dive into the research topics where Mark G. Currie is active.

Publication


Featured researches published by Mark G. Currie.


Bioorganic & Medicinal Chemistry Letters | 2008

In vitro and in vivo evaluation of O-alkyl derivatives of tramadol.

Liming Shao; Michael Charles Hewitt; Thomas P. Jerussi; Frank Xinhe Wu; Scott Christopher Malcolm; Paul Grover; Kevin Q. Fang; Patrick Koch; Chris H. Senanayake; Nandkumar N. Bhongle; Seth Ribe; Roger P. Bakale; Mark G. Currie

Tramadol is a centrally acting opioid analgesic structurally related to codeine and morphine. O-Alkyl, N-desmethyl, and non-phenol containing derivatives of tramadol were synthesized to probe their effect on metabolic stability and both in vitro and in vivo potency.


Arthritis & Rheumatism | 2002

Cyclooxygenase 2‐dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants

Medora M. Hardy; Karen Seibert; Pamela T. Manning; Mark G. Currie; B. Mark Woerner; Dorothy Edwards; Alane T. Koki; Catherine S. Tripp


Archive | 2003

Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide

Thomas P. Jerussi; Qun Kevin Fang; Mark G. Currie


Archive | 2002

Tramadol analogs and uses thereof

Chris H. Senanayake; Thomas P. Jerussi; Paul Grover; Qun Kevin Fang; Mark G. Currie


Archive | 2002

D-amino acid oxidase inhibitors for learning and memory

Donald L. Heefner; Mark G. Currie; Richard F. Rossi; Charles M. Zepp


Archive | 2010

Treatment of CNS Disorders with trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine

Thomas P. Jerussi; Qun Kevin Fang; Mark G. Currie


Archive | 2008

Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists

Mark G. Currie; Steve Jones; Paul Grover; Chris H. Senanayake; Q.Kevin Fang


Archive | 2002

Methods of using norfluoxetine

Mark G. Currie; Steven W. Jones; Chrisantha H. Senanayake; Zhi-hiu Lu


Archive | 2002

Methods of preparing and using 2-hydroxy derivatives of sibutramine and its metabolites

Chris H. Senanayake; Thomas P. Jerussi; Mark G. Currie; Qun K. Fang; Bob Hsu


Archive | 2004

Methods for treating depression and other CNS disorders using enantiomerically enriched desmethyl-and didesmethyl-metabolites of citalopram

Larry R. Bush; Mark G. Currie; Qun Kevin Fang; Chris H. Senanayake

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Paul T. Grover

Indiana University Bloomington

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