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Dive into the research topics where Mark Oram is active.

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Featured researches published by Mark Oram.


Molecular Biotechnology | 1995

A general assay for restriction endonucleases and other DNA-modifying enzymes with plasmid substrates

I. Barry Vipond; Geoffrey S. Baldwin; Mark Oram; Symon G. Erskine; Lois M. Wentzell; Mark D. Szczelkun; Timothy J. Nobbs; Stephen E. Halford

A procedure for measuring the activities of enzymes that alter the covalent structure of DNA is described. The assay utilizes covalently closed circles of DNA as the substrate and yields quantitative data on the fraction of this DNA converted to both open-circle and linear forms.


Current Biology | 1995

Recombination: Pieces of the site-specific recombination puzzle

Mark Oram; Mark D. Szczelkun; Stephen E. Halford

Understanding how nucleoprotein complexes interact with specific DNA sequences has come closer with structural and mechanistic studies of the interaction between the recombination enzyme resolvase and DNA.


Journal of Molecular Biology | 1997

Communications between distant sites on supercoiled DNA from non-exponential kinetics for DNA synapsis by resolvase.

Mark Oram; John F. Marko; Stephen E. Halford


Journal of Molecular Biology | 1997

Random walk models for DNA synapsis by resolvase

Richard B. Sessions; Mark Oram; Mark D. Szczelkun; Stephen E. Halford


Journal of Molecular Biology | 1995

Site-specific Recombination atresSites Containing DNA-binding Sequences for both Tn21 and Tn3 Resolvases

Panos Soultanas; Mark Oram; Stephen E. Halford


Current Biology | 1995

Pieces of the site-specific recombination puzzle

Mark Oram; Mark D Szczelkun; Stephen E. Halford


Biochemical Society Transactions | 1994

Synapsis by Tn3 resolvase: speed and dependence on DNA supercoiling

Mark Oram; Emma Shipstone; Stephen E. Halford


Biochemical Society Transactions | 1994

Purification and characterisation of the SfiI restriction endonuclease.

Lois M. Wentzell; Mark Oram; Stephen E. Halford


Biochemical Society Transactions | 1994

Purification and characterisation of the Sfil restriction endonuclease

Lois M. Wentzell; Mark Oram; Stephen E. Halford


Journal of Molecular Biology | 1997

Communications between distant sites on supercoiled DNA from non-exponential kinetics for DNA synapsis by resolvase 1 1 Edited by A. R. Fersht

Mark Oram; John F. Marko; Stephen E. Halford

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