Mark T. Jefferson
Pfizer
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Publication
Featured researches published by Mark T. Jefferson.
Journal of Industrial Microbiology & Biotechnology | 1988
Walter P. Cullen; Walter D. Celmer; Larry R. Chappel; Liang H. Huang; Mark T. Jefferson; Masaru Ishiguro; Hiroshi Maeda; Satoshi Nishiyama; John R. Oscarson; Riichiro Shibakawa; Junsuke Tone
SummaryCP-61,405 (C26H29N2O7Na) is a novel polycyclic pyrrolether antibiotic produced by a new species,Streptomyces routienii Huang sp. nov. (ATCC 39446). Recovery, fractionation and purification were achieved using standard procedures. The crystalline form includes the CP-61,405 sodium salt, m.p. 334–335°C, [α]D25°C+315°C (c=1, chloroform). The structure is shown below. CP-61,405 was co-produced with the polycyclic ether antibiotics salinomycin and epi-17-deoxy-(0–8)-salinomycin. It exhibited activity in vitro against gram-positive and anaerobic bacteria, efficacy against poultry coccidia and stimulation in vitro of propionic acid production.
The Journal of Antibiotics | 1989
Michael J. Range; John Cornish Ruddock; Michael S. Pacey; Walter P. Cullen; Liang H. Huang; Mark T. Jefferson; Earl B. Whipple; Hiroshi Maeda; Junsuke Tone
Archive | 1992
Walter P. Cullen; Mark T. Jefferson; Mikel P. Moyer
Journal of Organic Chemistry | 1986
Arthur Adam Nagel; Walter D. Celmer; Mark T. Jefferson; Lawrence A. Vincent; Earl B. Whipple; Gayle K. Schulte
Archive | 1975
Walter D. Celmer; Charles E. Moppett; Walter P. Cullen; John B. Routien; Mark T. Jefferson; Riichiro Shibakawa; Junsuke Tone
The Journal of Antibiotics | 1992
John P. Dirlam; Jon Bordner; Walter P. Cullen; Mark T. Jefferson; Laura Presseau-Linabury
Archive | 1978
Walter D. Celmer; Walter P. Cullen; Charles E. Moppett; Mark T. Jefferson; Liang H. Huang; Riichiro Shibakawa; Junsuke Tone
Archive | 1976
Walter D. Celmer; Liang H. Huang; Mark T. Jefferson; Hiroshi Maeda; Kozo Inoue; Riichiro Shibakawa
Archive | 1978
Walter D. Celmer; Walter P. Cullen; Charles E. Moppett; John B. Routien; Mark T. Jefferson; Riichiro Shibakawa; Junsuke Tone
Archive | 1977
Walter D. Celmer; Walter P. Cullen; Charles E. Moppett; John B. Routien; Mark T. Jefferson; Riichiro Shibakawa; Junsuke Tone
