Marta Fernández-Ayala

Surgical Site Infection During Hospitalization and After Discharge in Patients Who Have Undergone Cardiac Surgery

During a 13-month period, 513 patients who were scheduled to undergo cardiac surgery were prospectively observed for surgical site infection during hospitalization after surgery and for 1 month after hospital discharge. Fifty-three patients showed evidence of surgical site infection (during hospitalization for 31 patients and after discharge for 22). Multivariate analysis identified that risk factors for surgical site infection differed between infections that occurred during hospitalization and those that occurred after discharge.

Henoch-Schönlein purpura after intravesical administration of bacillus Calmette-Guérin

The administration of intravesical bacille Calmette-Guérin (BCG) in early stages of bladder cancer is usually a safe therapy. Side-effects of BCG immunotherapy can be of both local and systemic nature. We report the first case of Henoch-Schönlein purpura following intravesical administration of BCG.

Diabetes mellitus following cisplatin treatment.

The association between cisplatin treatment and diabetes mellitus was analyzed retrospectively in 219 patients with locally advanced squamous cell head and neck cancer treated in two consecutive trials with cisplatin-based induction chemotherapy. It was found that 11 patients (5%) developed diabetes mellitus during the treatment period, two cases presenting as hyperosmolar coma. The literature contains only sporadic descriptions of cases of hyperosmolar coma related to cisplatin chemotherapy. The present study was initiated owing to a case of hyperosmolar coma observed by us. We suggest that glycemia levels in patients receiving chemotherapy with a cisplatin-based regimen should be monitored regularly.

Varicella-Zoster Virus (VZV) Infection as a Possible Cause of Ogilvie's Syndrome in an Immunocompromised Host

ABSTRACT We describe an immunodeficient adult with Ogilvies syndrome preceding a disseminated papulovesicular skin rash in whom varicella-zoster virus infection was demonstrated by PCR assay in cutaneous and colonic biopsy specimens. In view of the significant morbidity and mortality that this condition carries, early and accurate molecular diagnosis and timely treatment are strongly recommended.

Postoperative Mediastinitis due to Salmonella

Mediastinitis remains one of the most serious and dreaded complications of median sternotomy. Salmonella is a rare cause of mediastinal infection. The case is reported of a patient who underwent heart valve surgery and developed a Salmonella enteritidis bacteraemia in the postoperative period, which caused aortic dissection and mediastinitis.