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Dive into the research topics where Martin A. Cheever is active.

Publication


Featured researches published by Martin A. Cheever.


Laryngoscope | 2000

Identification of genes overexpressed in head and neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis.

Douglas B. Villaret; Tongtong Wang; Davin C. Dillon; Jiangchun Xu; Dhileep Sivam; Martin A. Cheever; Steven G. Reed

Objectives/Hypothesis To discover unique genes specific for squamous cell carcinoma of the head and neck for eventual development as tumor markers and vaccine candidates.


Vaccine | 2001

Vaccination with Her-2/neu DNA or protein subunits protects against growth of a Her-2/neu-expressing murine tumor

Teresa M. Foy; Jeannette Bannink; Robert A Sutherland; Patricia D. Mcneill; Garner G Moulton; John M. Smith; Martin A. Cheever; Kenneth H. Grabstein

The present study utilizes an in vivo murine tumor expressing human Her-2/neu to evaluate potential Her-2/neu vaccines consisting of either full length or various subunits of Her-2/neu delivered in either protein or plasmid DNA form. Our results demonstrate that protective immunity against Her-2/neu-expressing tumor challenge can be achieved by vaccination with plasmid DNA encoding either full length or subunits of Her-2/neu. Partial protective immunity was also observed following vaccination with the intracellular domain (ICD), but not extracellular domain (ECD), protein subunit of Her-2/neu. The mechanism of protection elicited by plasmid DNA vaccination appeared to be exclusively CD4 dependent, whereas the protection observed with ICD protein vaccination required both CD4 and CD8 T cells.


Archive | 2000

Her-2/neu fusion proteins

Martin A. Cheever; Dirk Gheysen


Molecular Therapy | 2006

Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small-Cell Lung Cancer

John Nemunaitis; Thomas Meyers; Neil Senzer; C. C. Cunningham; Howard West; Eric Vallieres; Stephen P. Anthony; Svetislava J. Vukelja; Barry Berman; Heather Tully; Beena Pappen; Stephen Sarmiento; Rosemarie Arzaga; Steven Duniho; Susan Engardt; Madeleine Joy Meagher; Martin A. Cheever


Archive | 2001

Methods for diagnosis and therapy of hematological and virus-associated malignancies

Alexander Gaiger; Martin A. Cheever; Susan Hand-Zimmermann


Archive | 2001

Compositions and methods for the therapy and diagnosis of Her-2/neu-associated malignancies

Susan Hand-Zimmermann; Martin A. Cheever; Teresa M. Foy; Michael J. Lodes; Michael Kalos; Patricia D. Mcneill; Thomas S. Vedvick


Clinical Breast Cancer | 2003

HER2 Dendritic Cell Vaccines

Michael A. Morse; Timothy M. Clay; Kirsten Colling; Amy Hobeika; Ken Grabstein; Martin A. Cheever; H. Kim Lyerly


Archive | 2001

Compositions and methods for diagnosis and therapy of malignant mesothelioma

Martin A. Cheever; Alexander Gaiger


Archive | 2001

Compounds and methods for prevention and treatment of HER-2/neu associated malignancies

Martin A. Cheever; Susan Hand-Zimmermann


Vaccine | 2005

Cancer vaccines and immunotherapies: emerging perspectives

Robert A. Henderson; Sally Mossman; Natalie Nairn; Martin A. Cheever

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