Martin A. Cheever
Corixa Corporation
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Publication
Featured researches published by Martin A. Cheever.
Laryngoscope | 2000
Douglas B. Villaret; Tongtong Wang; Davin C. Dillon; Jiangchun Xu; Dhileep Sivam; Martin A. Cheever; Steven G. Reed
Objectives/Hypothesis To discover unique genes specific for squamous cell carcinoma of the head and neck for eventual development as tumor markers and vaccine candidates.
Vaccine | 2001
Teresa M. Foy; Jeannette Bannink; Robert A Sutherland; Patricia D. Mcneill; Garner G Moulton; John M. Smith; Martin A. Cheever; Kenneth H. Grabstein
The present study utilizes an in vivo murine tumor expressing human Her-2/neu to evaluate potential Her-2/neu vaccines consisting of either full length or various subunits of Her-2/neu delivered in either protein or plasmid DNA form. Our results demonstrate that protective immunity against Her-2/neu-expressing tumor challenge can be achieved by vaccination with plasmid DNA encoding either full length or subunits of Her-2/neu. Partial protective immunity was also observed following vaccination with the intracellular domain (ICD), but not extracellular domain (ECD), protein subunit of Her-2/neu. The mechanism of protection elicited by plasmid DNA vaccination appeared to be exclusively CD4 dependent, whereas the protection observed with ICD protein vaccination required both CD4 and CD8 T cells.
Archive | 2000
Martin A. Cheever; Dirk Gheysen
Molecular Therapy | 2006
John Nemunaitis; Thomas Meyers; Neil Senzer; C. C. Cunningham; Howard West; Eric Vallieres; Stephen P. Anthony; Svetislava J. Vukelja; Barry Berman; Heather Tully; Beena Pappen; Stephen Sarmiento; Rosemarie Arzaga; Steven Duniho; Susan Engardt; Madeleine Joy Meagher; Martin A. Cheever
Archive | 2001
Alexander Gaiger; Martin A. Cheever; Susan Hand-Zimmermann
Archive | 2001
Susan Hand-Zimmermann; Martin A. Cheever; Teresa M. Foy; Michael J. Lodes; Michael Kalos; Patricia D. Mcneill; Thomas S. Vedvick
Clinical Breast Cancer | 2003
Michael A. Morse; Timothy M. Clay; Kirsten Colling; Amy Hobeika; Ken Grabstein; Martin A. Cheever; H. Kim Lyerly
Archive | 2001
Martin A. Cheever; Alexander Gaiger
Archive | 2001
Martin A. Cheever; Susan Hand-Zimmermann
Vaccine | 2005
Robert A. Henderson; Sally Mossman; Natalie Nairn; Martin A. Cheever