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Dive into the research topics where Martin Brassard is active.

Publication


Featured researches published by Martin Brassard.


Bioorganic & Medicinal Chemistry Letters | 2008

Efficient parallel synthesis of macrocyclic peptidomimetics.

Eric Marsault; Hamid R. Hoveyda; René Gagnon; Mark L. Peterson; Martin Vezina; Carl Saint-Louis; Annick Landry; Jean François Pinault; Luc Ouellet; Sophie Beauchemin; Sylvie Beaubien; Axel P. Mathieu; Kamel Benakli; Zhigang Wang; Martin Brassard; David Lonergan; François Bilodeau; Mahesh Ramaseshan; Nadia Fortin; Ruoxi Lan; Shigui Li; Fabrice Galaud; Véronique Plourde; Manon Champagne; Annie Doucet; Patrick Bherer; Maude Gauthier; Gilles Olsen; Gérald Villeneuve; Shridhar Bhat

A new method for solid phase parallel synthesis of chemically and conformationally diverse macrocyclic peptidomimetics is reported. A key feature of the method is access to broad chemical and conformational diversity. Synthesis and mechanistic studies on the macrocyclization step are reported.


Journal of Medicinal Chemistry | 2011

Optimization of the Potency and Pharmacokinetic Properties of a Macrocyclic Ghrelin Receptor Agonist (Part I): Development of Ulimorelin (TZP-101) from Hit to Clinic

Hamid R. Hoveyda; Eric Marsault; René Gagnon; Axel P. Mathieu; Martin Vezina; Annick Landry; Zhigang Wang; Kamel Benakli; Sylvie Beaubien; Carl Saint-Louis; Martin Brassard; Jean François Pinault; Luc Ouellet; Shridhar Bhat; Mahesh Ramaseshan; Xiaowen Peng; Laurence Foucher; Sophie Beauchemin; Patrick Bherer; Daniel F. Veber; Mark L. Peterson; Graeme Fraser


Archive | 2008

Macrocyclic Ghrelin Receptor Modulators and Methods of Using the Same

Hamid R. Hoveyda; Graeme Fraser; Kamel Benakli; Sophie Beauchemin; Martin Brassard; David J. Drutz; Eric Marsault; Luc Ouellet; Mark L. Peterson; Zhigang Wang


Archive | 2010

Macrocyclic ghrelin receptor antagonists and inverse agonists and methods of using the same

Hamid R. Hoveyda; Eric Marsault; Helmut Thomas; Graeme Fraser; Sylvie Beaubien; Axel P. Mathieu; Julien Beignet; Marc-André Bonin; Serge Phoenix; David J. Drutz; Mark L. Peterson; Sophie Beauchemin; Martin Brassard; Martin Vezina


Archive | 2011

Modified macrocyclic ghrelin receptor modulators and methods of using the same

Eric Marsault; Helmut Thomas; Patrick Bherer; Lilian Clohs; Sophie Beauchemin; Martin Brassard; Felix Dupont; Serge Phoenix; Martin Vezina


Advances in Experimental Medicine and Biology | 2009

High Throughput Solid Phase Parallel Synthesis of Macrocyclic Peptidomimetics

Eric Marsault; Hamid R. Hoveyda; Mark L. Peterson; René Gagnon; Martin Vezina; Jean François Pinault; Annick Landry; Carl Saint-Louis; L. G. Ouellet; Sophie Beauchemin; Kamel Benakli; Sylvie Beaubien; Martin Brassard; Zhigang Wang; M. Champagne; F. Galaud; N. Fortin; Daniel Fortin; V. Plourde; Mahesh Ramaseshan; Shridhar Bhat; François Bilodeau; D. Lonergan; Ruoxi Lan; Shigui Li; Gilles Berthiaume; Laurence Foucher; Xiaowen Peng; Yves L. Dory; Pierre Deslongchamps


Archive | 2008

tether intermediates for the synthesis of macrocyclic ghrelin receptor modulators

Hamid Hoveyda; Graeme Fraser; Sophie Beauchemin; Martin Brassard; David J. Drutz; Eric Marsault; Luc Quellet; Mark L. Peterson; Zhigang Wang; Kamel Benkali


Archive | 2008

Productos intermedios conectores para la síntesis de moduladores macrocíclicos del receptor de la grelina

Hamid Hoveyda; Graeme Fraser; Sophie Beauchemin; Martin Brassard; David J. Drutz; Eric Marsault; Luc Quellet; Mark L. Peterson; Zhigang Wang; Kamel Benkali


Archive | 2008

Intermediaten für die Synthese von Makrozyklische Ghrelin-Rezeptormodulatoren

Hamid Hoveyda; Graeme Fraser; Sophie Beauchemin; Martin Brassard; David J. Drutz; Eric Marsault; Luc Quellet; Mark L. Peterson; Zhigang Wang; Kamel Benkali


Archive | 2008

macrocyclic receptor modulators ghrelin and methods of use thereof

Hamid Hoveyda; Graeme Fraser; Sophie Beauchemin; Martin Brassard; David J. Drutz; Eric Marsault; Luc Ouellet; Mark L. Peterson; Zhigang Wang; Kamel Benakli

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Eric Marsault

Université de Sherbrooke

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