Martina Palomba

Recent advances in the chemistry of vinylchalcogenides

GRAPHICAL ABSTRACT ABSTRACT Vinyl selenides, sulfides and tellurides surely represent important compounds in organic chemistry for their relatively easy accessibility and synthetic utility. More than the others vinyl selenides showed interesting biological activities such as the ability to reduce oxidative stress. New methods for the synthesis of vinyl thioethers have been developed in the last few years placing such compounds in a prominent position from an organic chemistry perspective. Tellurides are endowed with unique properties that make them suitable alternatives or precursors to organometallic species. The most recent and interesting examples about the chemistry of vinyl chalcogenides will be collected in this minireview.

Domino Processes for the Synthesis of N-Vinylazoles Starting From Vinyl Selenones

A novel and simple strategy for the synthesis of N-vinylazoles has been developed starting from vinyl selenones. This reaction occurs via aza-Michael addition/elimination cascade. This method is applicable to a wide range of vinyl selenones and mono and di-azoles. N-vinylazoles were obtained in good yields under mild reaction conditions. They are important building blocks in organic synthesis and also key structural motif in medicinal chemistry. Moreover, N-vinylazoles have been shown to serve as monomers for the synthesis of poly(N-vinylazoles).