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Dive into the research topics where Mary A Fletcher is active.

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Featured researches published by Mary A Fletcher.


Journal of Psychosomatic Research | 2003

Emotional expression and depth processing of trauma and their relation to long-term survival in patients with HIV/AIDS

Conall O'Cleirigh; Gail Ironson; Michael H. Antoni; Mary A Fletcher; Lisa McGuffey; Elizabeth Balbin; Neil Schneiderman; George F. Solomon

OBJECTIVE This study examined the relationship between emotional expression and depth processing of trauma and long-term survival of patients living with AIDS. A further purpose was to examine the immune, health behavior and psychosocial correlates of emotional disclosure and depth processing. METHOD Subjects wrote essays describing their reactions to past traumas; these were scored for emotional expression and depth processing (positive cognitive appraisal change, experiential involvement, self-esteem enhancement and adaptive coping strategies). Two HIV-seropositive groups were recruited for this study; long-term survivors (LTS; n=46) patients who had survived at least 4 years past a Category C (AIDS defining) symptom prior to starting protease inhibitors and an equivalent HIV-seropositive comparison group (ECOMP(LTS); n=89) who had CD4+ cells between 150 and 500, and had no history of Category C symptoms. The groups were equivalent on age, gender, ethnicity, education, employment, income, sexual orientation and route of infection. RESULTS The group LTS were significantly higher than the ECOMP(LTS) group on emotional expression and depth processing. Depth processing mediated the relationship between emotional expression and long-term survival status. Depth processing was positively related to CD4+ cell number for women. Emotional expression was also significantly related to viral load (negatively) and to CD4+ cell number (positively) for women only. Interestingly, only depth processing (and not emotional expression) was related to medication adherence and to psychosocial variables (perceived stress and social support). CONCLUSIONS Emotional expression and depth processing were related to long-term survival, however, depth processing was the mediator for this relationship and only depth processing was associated with medication adherence, perceived stress and social support. Our results underscore the importance of depth processing (and not just emotional expression) of traumatic experiences for people living with HIV/AIDS.


American Society for Microbiology | 1992

Lymphocyte Proliferation Assays

Mary A Fletcher; Nancy G. Klimas; R. Morgan; George F. Gjerset


Journal of Psychosomatic Research | 2006

Anger suppression mediates the relationship between optimism and natural killer cell cytotoxicity in men treated for localized prostate cancer.

Frank J. Penedo; Jason R. Dahn; Dave Kinsinger; Michael H. Antoni; Ivan Molton; Jeffrey S. Gonzalez; Mary A Fletcher; Bernard A. Roos; Charles S. Carver; Neil Schneiderman


Archive | 2006

View of God is Associated with Disease Progression in HIV

Mary A Fletcher; Gail Ironson; R. Stuezle


Archive | 2014

Analyzing immune signaling networks for identification of therapeutic targets in complex chronic medical disorders

Mary A Fletcher; Gordon Broderick; Nancy G. Klimas


Archive | 2011

The Use of Comprehensive Molecular Profiling with Network and Control Theory to Better Understand GWI and Model Therapeutic Strategies

Nancy G. Klimas; Mary A Fletcher


Archive | 2007

Perceived stress and norepinepherine predict the effectiveness of the response to protenase inhibitor medication in HIV

Mary A Fletcher; Gail Ironson; Elizabeth Balbin; E. Stieren; K. Detz; N. Scheniderman; Mahendra Kumar


Archive | 2002

Psychosocial factors related to sustained health in HIV. . 7th International Congress of Behavioral Medicine

Mary A Fletcher; Gail Ironson; George F. Solomon; Elizabeth Balbin; Conall O'Cleirigh; N. Schneiderman


Archive | 1999

Associations Between Viral Load, Natural Killer Cell (CD56+CD3-) Number, and State Anxiety among HIV Seropositive Men

Mary A Fletcher; Kevin Maher; Dean G. Cruess; M. Antoni; N. Schneiderman; Nancy G. Klimas


Archive | 1998

Patterns of Immune Reconstitution in HIV-1 Infection Following Highly Active Anti-Retro-viral Therapy

Mary A Fletcher; Kevin Maher; Nancy G. Klimas; Gordon M. Dickinson; J. Triplett; C. Maggio; R. Valenzuela

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