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Dive into the research topics where Mary C. Santos is active.

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Featured researches published by Mary C. Santos.


Journal of Pediatric Surgery | 2015

An implemented MRI program to eliminate radiation from the evaluation of pediatric appendicitis

Afif N. Kulaylat; Michael M. Moore; Brett W. Engbrecht; James M. Brian; Aliasgher Khaku; Dorothy V. Rocourt; Michael A. Hulse; Robert P. Olympia; Mary C. Santos; Sosamma Methratta; Peter W. Dillon; Robert E. Cilley

BACKGROUND Recent efforts have been directed at reducing ionizing radiation delivered by CT scans to children in the evaluation of appendicitis. MRI has emerged as an alternative diagnostic modality. The clinical outcomes associated with MRI in this setting are not well-described. METHODS Review of a 30-month institutional experience with MRI as the primary diagnostic evaluation for suspected appendicitis (n=510). No intravenous contrast, oral contrast, or sedation was administered. Radiologic and clinical outcomes were abstracted. RESULTS MRI diagnostic characteristics were: sensitivity 96.8% (95% CI: 92.1%-99.1%), specificity 97.4% (95% CI: 95.3-98.7), positive predictive value 92.4% (95% CI: 86.5-96.3), and negative predictive value 98.9% (95% CI: 97.3%-99.7%). Radiologic time parameters included: median time from request to scan, 71 minutes (IQR: 51-102), imaging duration, 11 minutes (IQR: 8-17), and request to interpretation, 2.0 hours (IQR: 1.6-2.6). Clinical time parameters included: median time from initial assessment to admit order, 4.1 hours (IQR: 3.1-5.1), assessment to antibiotic administration 4.7 hours (IQR: 3.9-6.7), and assessment to operating room 9.1 hours (IQR: 5.8-12.7). Median length of stay was 1.2 days (range: 0.2-19.5). CONCLUSION Given the diagnostic accuracy and favorable clinical outcomes, without the potential risks of ionizing radiation, MRI may supplant the role of CT scans in pediatric appendicitis imaging.


Journal of Pediatric Surgery | 2014

Transumbilical laparoscopic-assisted appendectomy is associated with lower costs compared to multiport laparoscopic appendectomy.

Afif N. Kulaylat; Abigail B. Podany; Mary C. Santos; Dorothy V. Rocourt

BACKGROUND/PURPOSE Single-incision laparoscopic appendectomy has been associated with improved cosmetic benefits, and decreased postoperative pain. Less is known about costs and other outcomes. Our aim was to evaluate the costs and outcomes between transumbilical laparoscopic-assisted appendectomy (TULAA) and multiport laparoscopic appendectomy (MLA). METHODS IRB-approved retrospective review (September 2010-July 2013) of institutional medical records identified 372 pediatric patients undergoing laparoscopic appendectomy. Outcomes included costs, LOS and readmission. Costs were fully loaded operating costs from the hospitals cost accounting database. Generalized linear regression was used to assess costs of MLA and TULAA. A subgroup analysis was performed using only patients with non-perforated appendicitis. RESULTS There were 132 patients (35.5%) that underwent TULAA while 240 patients (65.5%) underwent MLA. Compared to MLA, TULAA was associated with decreased operative time (0.6 vs. 1.0h, p<0.0001), used in comparable proportions of interval appendectomies, but was performed less often for perforated appendicitis (9.8% vs. 22.9%, p=0.002). Readmission and postoperative complications were similar between both groups. In the setting of non-perforated appendicitis, TULAA was associated with lower costs of


Journal of Pediatric Surgery | 2015

Endobronchial occlusion with one-way endobronchial valves: A novel technique for persistent air leaks in children

Jennifer Toth; Abigail B. Podany; Michael F. Reed; Dorothy V. Rocourt; Christopher R. Gilbert; Mary C. Santos; Robert E. Cilley; Peter W. Dillon

1378 relative to MLA (p=0.009). CONCLUSIONS In non-perforated appendicitis, TULAA is associated with lower costs and comparable rates of readmission and postoperative complications.


Clinical Pediatrics | 2014

Short-term Outcomes of Sport- and Recreation-Related Concussion in Patients Admitted to a Pediatric Trauma Service

Harry Bramley; Carol Mcfarland; Mechelle M. Lewis; Michele L. Shaffer; Robert E. Cilley; Brett W. Engbrecht; Mary C. Santos; Susan Rzucidlo; Beverly Shirk; Lynn Simmons; Mark S. Dias

PURPOSE In children, persistent air leaks can result from pulmonary infection or barotrauma. Management strategies include surgery, prolonged pleural drainage, ventilator manipulation, and extracorporeal membrane oxygenation (ECMO). We report the use of endobronchial valve placement as an effective minimally invasive intervention for persistent air leaks in children. METHODS Children with refractory prolonged air leaks were evaluated by a multidisciplinary team (pediatric surgery, interventional pulmonology, pediatric intensive care, and thoracic surgery) for endobronchial valve placement. Flexible bronchoscopy was performed, and air leak location was isolated with balloon occlusion. Retrievable one-way endobronchial valves were placed. RESULTS Four children (16 months to 16 years) had prolonged air leaks following necrotizing pneumonia (2), lobectomy (1), and pneumatocele (1). Patients had 1-4 valves placed. Average time to air leak resolution was 12 days (range 0-39). Average duration to chest tube removal was 25 days (range 7-39). All four children had complete resolution of air leaks. All were discharged from the hospital. None required additional surgical interventions. CONCLUSION Endobronchial valve placement for prolonged air leaks owing to a variety of etiologies was effective in these children for treating air leaks, and their use may result in resolution of fistulae and avoidance of the morbidity of pulmonary surgery.


Journal of the Pancreas | 2013

Isolated pediatric pancreatic transection secondary to ocean-related trauma.

Afif N. Kulaylat; Mary C. Santos

The outcomes of patients admitted to the hospital following a sport-related concussion are largely unknown. Medical records of patients admitted to the pediatric trauma service between 2008 and 2011 after sustaining a sport-related concussion were reviewed. In all, 59 participants were in the high-velocity activities group, and 21 in the field or court sport group. Abnormal CT scans were found in 14 patients in the high-velocity group and 2 in the field or court sport group. The majority of participants in the field or court sport group were football players, all of whom had normal CT scans. Headache was predictive of an abnormal CT scan. Among the patients, 56% clinically improved and were discharged the following day. Patients with field or court sport–related concussion admitted to a pediatric trauma service appear to be at low risk for clinically significant intracranial pathology and do well in the acute setting.


Journal of Pediatric Surgery | 2009

Use of computed tomography to categorize the type of tracheal agenesis

Indira D. Panthagani; Mary C. Santos; Carl T. D'Angio

CONTEXT Isolated pancreatic transection is a rare but well-recognized complication following blunt trauma of the abdomen. Diagnosis at presentation may be difficult and delayed due to subtle initial symptoms and evolving nature of the injury. CASE REPORT We describe an isolated complete pancreatic transection in a 14-year-old female secondary to a previously unreported and highly unusual mechanism (being tossed by a wave). Diagnosis was obtained by computed tomography scan 24 hours following initial trauma. She was managed operatively with an open distal pancreatectomy with splenic preservation and no subsequent complications. CONCLUSIONS The force sustained from the blunt abdominal trauma of being tossed by a wave can be significant. The management of pancreatic injuries in children, particularly in the context of ductal transection, is controversial. Timely recognition and management is critical to optimal outcomes. Early operative intervention may help to avoid complications such as abscess or pseudocyst formation.


Journal of Anesthesia and Clinical Research | 2012

Diagnosis and Airway Management in a Neonate with Laryngeal Atresia, Tracheal Agenesis and a Broncho-Esophageal Fistula: A Case Report

Jodi Bosak; Eric Pauli; Mary C. Santos; Brett W. Engbrecht; Priti G. Dalal

We report a case of type I tracheal agenesis with vertebral defects, anal atresia, tracheoesophageal fistula and/or esophageal atresia, radial dysplasia, renal defects, and cardiovascular defects association in which computed tomography was helpful in categorizing the diagnosis. This rare and fatal condition should always be considered when confronted with a neonate impossible to resuscitate at birth.


Journal of Pediatric Surgery | 2017

Understanding readmissions in children undergoing surgery: A pediatric NSQIP analysis

Afif N. Kulaylat; Dorothy V. Rocourt; Anthony Y. Tsai; Kathryn Martin; Brett W. Engbrecht; Mary C. Santos; Robert E. Cilley; Peter W. Dillon

Tracheal agenesis is a rare congenital anomaly that is usually fatal and occurs in approximately 1:50,000 births. The diagnosis is usually made when there is failure to perform endotracheal intubation in a neonate with severe respiratory distress and absence of audible cry. We present a case of a newborn with suspected trachea-esophageal fistula who presented to the operating room for ligation of the fistula. The diagnosis of laryngeal atresia with tracheal agenesis was made intraoperatively when attempts at surgical ligation of the fistula resulted in difficulty with ventilation and a loss of the capnograph. Ventilation of the lungs was possible with an esophageally placed tube via an esophago-bronchial fistula. This case highlights the importance and need for good communication and teamwork between surgeons, anesthesiologist, radiologist and neonatologists.


Pediatric Emergency Care | 2016

Delayed Presentation of Jejuno-Jejunal Fistula With Stricture After Physical Child Abuse

Adil Z. Solaiman; Afif N. Kulaylat; Mary C. Santos; Dorothy V. Rocourt; Sosamma Methratta; Karmaine Millington; Chandran Alexander

BACKGROUND Readmission is increasingly being utilized as an important clinical outcome and measure of hospital quality. Our aim was to delineate rates, risk factors, and reasons for unplanned readmission in pediatric surgery. MATERIALS AND METHODS Retrospective review of pediatric patients (n=130,274) undergoing surgery (2013-2014) at hospitals enrolled in the Pediatric National Surgical Quality Improvement Program (NSQIP-P) was performed. Logistic regression was used to model factors associated with unplanned 30-day readmission. Reasons for readmission were reviewed to determine the most common causes of readmission. RESULTS There were 6059 (n=4.7%) readmitted children within 30days of the index operation. Of these, 5041 (n=3.9%) were unplanned, with readmission rates ranging from 1.3% in plastic surgery to 5.2% in general pediatric surgery, and 10.8% in neurosurgery. Unplanned readmissions were associated with emergent status, comorbidities, and the occurrence of pre- or postdischarge postoperative complications. Overall, the most common causes for readmission were surgical site infections (23.9%), ileus/obstruction/gastrointestinal (16.8%), respiratory (8.6%), graft/implant/device-related (8.1%), neurologic (7.0%), or pain (5.8%). Median time from discharge to readmission was 8days (IQR: 3-14days). Reasons for readmission, time until readmission, and need for reoperative procedure (overall 28%, n=1414) varied between surgical specialties. CONCLUSION The reasons for readmission in children undergoing surgery are complex, varied, and influenced by patient characteristics and postoperative complications. These data inform risk-stratification for readmission in pediatric surgical populations, and help to identify potential areas for targeted interventions to improve quality. They also highlight the importance of accounting for case-mix in the interpretation of hospital readmission rates. LEVEL OF EVIDENCE 3.


Journal of Surgical Education | 2014

Collaborating to increase access to clinical and educational resources for surgery: a case study.

Jonathan M. Tomasko; Nancy E. Adams; Frank G. Garritano; Mary C. Santos; Peter W. Dillon

Abstract Small intestinal injury is seldom described in the context of child abuse. Signs and symptoms are subtle, often leading to delays in diagnosis. We describe a 3-year-old boy initially admitted with severe blunt abdominal trauma from physical child abuse. He was successfully managed nonoperatively. The child was then hospitalized several times for nonspecific abdominal symptoms until diagnostic laparoscopy discovered a jejunal stricture with a proximal jejuno-jejunal fistula. Symptoms fully resolved after resection. Delayed presentation of small intestinal injury should remain on the differential diagnosis in the evaluation of persistent abdominal symptoms in a child with a prior history of physical abuse, even if imaging studies do not reveal specific abnormalities.

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Afif N. Kulaylat

Pennsylvania State University

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Brett W. Engbrecht

Pennsylvania State University

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Peter W. Dillon

Pennsylvania State University

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Robert E. Cilley

Pennsylvania State University

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Abigail B. Podany

Penn State Milton S. Hershey Medical Center

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Sosamma Methratta

Penn State Milton S. Hershey Medical Center

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Adil Z. Solaiman

Pennsylvania State University

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Aliasgher Khaku

Pennsylvania State University

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Anthony Y. Tsai

Boston Children's Hospital

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