Masahide Yamada

Preparation of a water-soluble acylating agent: benzoylation of acids, amines, and phenols with 2-benzoylthio-1-methylpyridinium chloride in aqueous phase

2-Benzoylthio-1-methylpyridinium chloride, prepared from benzoyl chloride and 1-methyl-2(1H)-pyridothione, is found to act as an acylating agent in aqueous phase.

Reduction of 1,2;5,6-di-O-isopropylidene-α-d-glucofuranose derivatives with lithium aluminium hydride; a facile syntehtic method for 3,6-imino derivatives

Abstract Treatment of 3-acylamido- or alkylimino-3-deoxy-1,2;5,6-di- O -isopropylidene-α- d -glucofuranose with lithium aluminum hydride in boiling 1,4-dioxane afforded unusual products, namely, 3,6- N -alkylimino-3,6-dideoxy-1,2- O -isopropylidene-α- d -glucofuranose or 6- O -isopropyl-1,2- O -isopropylidene-α- d -glucofuranose derivatives. 3,6- N -(Benzyloxy)imino-3,6-dideoxy-1,2- O -isopropylidene-β- l -idofuranose, a key intermediate for synthesis of anisomycin, was prepared by use of this reaction.