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Dive into the research topics where Masahiko Sawaguchi is active.

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Featured researches published by Masahiko Sawaguchi.


European Journal of Pharmacology | 1990

Blocking effect of 1389-S on the sodium current in isolated guinea-pig ventricular myocytes.

Ichiro Hisatome; Satoshi Matsuoka; Jiro Miyamoto; Masahiko Sawaguchi; Hiroki Omadani; Shuichi Osaki; Hiroshi Kotake; Hiroto Mashiba; Ryoichi Sato

Under whole cell patch conditions, 1389-S blocked the INa in guinea-pig ventricular myocytes under steady state conditions (Kdrest = 30 microM, Kdi = 2.4 microM) with a shift of the inactivation curve to the hyperpolarizing direction. Both brief and long conditioning pulses could produce a use-dependent block of 1389-S. These results suggest that 1389-S had a higher affinity to the inactivated than to the rested state under steady state conditions and had a higher affinity to the activated state during train pulses as well as to the inactivated state, making channels unavailable for conduction upon activation.


Internal Medicine | 1996

Renal handling of urate in a patient with familial juvenile gouty nephropathy

Ichiro Hisatome; Hiromoto Kosaka; Keiko Ohtahara; Mariko Tsuboi; Ichiro Manabe; Akira Ohtahara; Masahiko Sawaguchi; Osamu Igawa; Yasushi Tanaka; Yukihiro Fujimoto; Akio Yoshida; Akira Takeda; Chiaki Shigemasa


Japanese Circulation Journal-english Edition | 1997

ENT DURING SEQUENTIAL VENTRICULO : ATRIAL PACING IN THE PATIENTS WITH THE WPW SYNDROME

Toshimitsu Suga; Osamu Igawa; Akira Tomokuni; Masahiko Sawaguchi; Masamitsu Adachi; Akio Yano; Yoshiaki Inoue; Junichirou Miake; Shinya Fujita; Yumi Yamanouchi; Ichirou Hisatome; Chiaki Shigemasa


Japanese Circulation Journal-english Edition | 1996

0002 THE RELATIONSHIP BETWEEN THE MORPHOLOGIC FEATURES OF THE CORONARY SINUS AND THE LACATION OF THE ACCESSORY PATHWAY IN THE PATIENTS WITH THE WPW SYNDROMES

Toshimitsu Suga; Osamu Igawa; Akira Tomokuni; Masahiko Sawaguchi; Masamitsu Adachi; Akio Yano; Junichiro Miake; Yoshiaki Inoue; Satoshi Miyazaki; Ichirou Hisatome; Chiaki Shigemasa


Japanese Circulation Journal-english Edition | 1996

0003 THE DIMENSIONS OF KOCH'S TRIANGLE IN JAPANESE PATIENTS

Masamitsu Adachi; Osamu Igawa; Akira Tomokuni; Masahiko Sawaguchi; Toshimitsu Suga; Akio Yano; Junichiro Miake; Yoshiaki Inoue; Satoshi Miyazaki; Ichirou Hisatome; Chiaki Shigemasa


Japanese Circulation Journal-english Edition | 1996

0010 FACTORS RELATED TO IMPAIRMENT OF ATRIOVENTRICULAR CONDUCTION OVER THE FAST PATHWAY IN DELIVERING RADIOFREQUENCY CURRENT NEAR THE CORONARY SINUS OSTIUM

Masahiko Sawaguchi; Osamu Igawa; Akira Tomokuni; Toshimitsu Suga; Akio Yano; Junichiro Miake; Yoshiaki Inoue; Chiaki Shigemasa


Japanese Circulation Journal-english Edition | 1995

-0645- Effects of disopyramide on th electrophysiological characteristics of the retrograde accessory pathway conduction in the standing position(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)

Akira Tomokuni; Osamu Igawa; Masahiko Sawaguchi; Toshimitsu Suga; Akio Yano; Masamitsu Adachi; Junichiro Miake; Satoshi Miyazaki; Hirosi Kotake; Hiroto Mashiba


Japanese Circulation Journal-english Edition | 1995

-P243- The Problems in Evaluating Electrophysiological Characteristics of Accessory Pathway(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)

Toshimitsu Suga; Osamu Igawa; Akira Tomokuni; Masahiko Sawaguchi; Satoshi Miyazaki; Masamitsu Adachi; Akio Yano; Junichiro Miake; Yoshiaki Inoue; Hiroshi Kotake; Hiroto Mashiba


Japanese Circulation Journal-english Edition | 1995

-P240- Changes of Atrial Refractoriness during Atrioventricular Reentrant Tachycardia in Patients with Wolff-Parkinson-White Syndrome:Relevance to Paroxysmal Atrial Fibrillation(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)

Masamitsu Adachi; Osamu Igawa; Akira Tomokuni; Masahiko Sawaguchi; Toshimitsu Suga; Akio Yano; Junichiro Miake; Satoshi Miyazaki; Hiroshi Kotake; Hiroto Mashiba


Japanese Circulation Journal-english Edition | 1994

Changes of coagulation and fibrinolysis after radiofrequency catheter ablation

Osamu Igawa; Akira Tomokuni; Masahiko Sawaguchi; Toshimitsu Suga; Akio Yano; Masamitsu Adachi; Junichiro Miake; Satoshi Miyazaki; Hiroshi Kotake; Hiroto Mashiba

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Satoshi Miyazaki

Memorial Hospital of South Bend

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