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Masaji Kasai

Arai Helmet

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Publication

Featured researches published by Masaji Kasai.

Expert Opinion on Therapeutic Patents | 1995

Review: Anti-infectives Novel mitomycin derivatives

Masaji Kasai; Hitoshi Arai

Modification studies describing the synthesis of a number of mitomycin derivatives that have appeared in the patent literature during recent years are reviewed. Particular emphasis is placed on the design of the derivatives and their preparation. Biological activities, reaction schemes and structure-activity relationships for the derivatives are also mentioned in this review.

Synthetic Communications | 1989

Improved Synthesis of Mitomycin G

Motomichi Kono; Masaji Kasai; Kunikatsu Shirahata

Abstract Mitomycin G 2 was derived from mitomycin B 5 by 3 steps in an overall yield of 43 %.

The Journal of Antibiotics | 1980

Novel Antitumor Antibiotics, Tetrocarcins

Fusao Tomita; Tatsuya Tamaoki; Kunikatsu Shirahata; Masaji Kasai; Makoto Morimoto; Shuji Ohkubo; Kazuyuki Mineura; Shinzo Ishii

The Journal of Antibiotics | 1980

Tetrocarcins, novel antitumor antibiotics. II. Isolation, characterization and antitumor activity.

Tatsuya Tamaoki; Masaji Kasai; Kunikatsu Shirahata; Shuji Ohkubo; Makoto Morimoto; Kazuyuki Mineura; Shinzo Ishii; Fusao Tomita

Cancer Research | 1993

Adducts of Mitomycin C and DNA in EMT6 Mouse Mammary Tumor Cells: Effects of Hypoxia and Dicumarol on Adduct Patterns

Roland Bizanek; Dondapati Chowdary; Hitoshi Arai; Masaji Kasai; Christine S. Hughes; Alan C. Sartorelli; Sara Rockwell; Maria Tomasz

Cancer Research | 1991

Antitumor Activity of 7-N-{{2-{[2-(γ-l-Glutamylamino)ethyl]dithio}ethyl}}-mitomycin C

Makoto Morimoto; Tadashi Ashizawa; Hiroe Ohno; Mitsuhiko Azuma; Eiji Kobayashi; Masami Okabe; Katsushige Gomi; Motomichi Kono; Yutaka Saitoh; Yutaka Kanda; Hitoshi Arai; Akira Sato; Masaji Kasai; Takashi Tsuruo

Chemical & Pharmaceutical Bulletin | 1989

SYNTHESIS AND ANTITUMOR ACTIVITY OF A NOVEL WATER SOLUBLE MITOMYCIN ANALOG; 7-N-[2-[[2-(γ-L-GLUTAMYLAMINO)ETHYL]DITHIO]ETHYL]MITOMYCIN C

Motomichi Kono; Yutaka Saitoh; Masaji Kasai; Akira Sato; Kunikatsu Shirahata; Makoto Morimoto; Tadashi Ashizawa

The Journal of Antibiotics | 1982

TETROCARCINS E1, E2, F AND F-1, NEW ANTIBIOTICS FERMENTATION, ISOLATION AND CHARACTERIZATION

Tatsuya Tamaoki; Masaji Kasai; Kunikatsu Shirahata; Fusao Tomita

Oncology Research | 1998

Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C.

Yolanda Palom; Michael F. Belcourt; Gopinatha Suresh Kumar; Hitoshi Arai; Masaji Kasai; Alan C. Sartorelli; Sara Rockwell; Maria Tomasz

Bulletin of the Chemical Society of Japan | 1982

The Crystal and Molecular Structures of Tetronolide

Noriaki Hirayama; Masaji Kasai; Kunikatsu Shirahata; Yuji Ohashi; Yoshio Sasada

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Kunikatsu Shirahata

Tohoku University

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Akira Sato

Toshiba

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Eiji Kobayashi

Osaka University

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Fusao Tomita

Hokkaido University

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Shiro Akinaga

National Institutes of Health

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Tadashi Ashizawa

Eli Lilly and Company

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Noriaki Hirayama

Tokai University

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Yoshio Sasada

Osaka University

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Yuji Ohashi

Tohoku University

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Alan C. Sartorelli

Yale University

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