Masami Senma
Kanazawa Medical University
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Featured researches published by Masami Senma.
Archives of Environmental Health | 1993
Hideaki Nakagawa; Muneko Nishijo; Yuko Morikawa; Masaji Tabata; Masami Senma; Yumiko Kitagawa; Shunichi Kawano; Masao Ishizaki; Naomichi Sugita; Masami Nishi; Teruhiko Kido; Koji Nogawa
A 9-y follow-up study of 3,178 persons who lived in a cadmium-polluted area was conducted to assess the influence of environmental cadmium exposure on long-term outcome. The standardized mortality ratios of the urinary beta 2-microglobulin-positive subjects (> 1,000 micrograms/g creatinine) of both sexes were higher than those of the general Japanese population, whereas the cumulative survival curves were lower than those of the urinary beta 2-microglobulin-negative group. A significant association was also found between urinary beta 2-microglobulin and mortality, using a Coxs proportional hazards model. Moreover, mortality rates increased in proportion to increases in the amount of urinary beta 2-microglobulin excreted. These results suggest that the prognosis for cadmium-exposed subjects with proximal tubular dysfunction is unfavorable. The mortality rate tended to become higher as the severity of renal dysfunction progressed.
Archives of Environmental Health | 1990
Hideaki Nakagawa; Masaji Tabata; Yuko Morikawa; Masami Senma; Yumiko Kitagawa; Shunichi Kawano; Teruhiko Kido
A follow-up study was conducted from 1967 to 1987 for patients diagnosed as having itai-itai disease, subjects who were suspected of having the disease, and controls. Ninety-five subjects per category were selected after matching for age, sex, and residential area. The cumulative survival rate of the patients who had a definite diagnosis of itai-itai disease was significantly lower than that of the control group in every period after the first 3 y. The cumulative survival rate of the subjects who were suspected of having itai-itai disease and who had severe renal dysfunction due to cadmium pollution was significantly lower than that of the control group. These results demonstrate (1) the enduring negative influence of itai-itai disease on prognosis and (2) that the cadmium pollution-induced renal disorder adversely affects the health of the inhabitants of a cadmium-polluted area.
Journal of Hypertension | 1995
Katsuyuki Miura; Hideaki Nakagawa; Muneko Nishijo; Masaji Tabata; Yuko Morikawa; Masami Senma; Katsushi Yoshita; Masao Ishizaki; Shunichi Kawano
Objective To determine whether blood pressure within the normal range is associated with plasma insulin concentration in a Japanese population with normal glucose tolerance. Methods We studied 491 normotensive Japanese men with normal glucose tolerance, who had never been treated with antihypertensive medications. Plasma glucose and insulin response during a 75-g oral glucose-tolerance test, blood pressure, body mass index, serum lipids, alcohol consumption and smoking status were obtained. The subjects were divided into quartiles according to mean blood pressure level (< 79, 79–84, 85–91 and ≥92 mmHg). To eliminate possible confounding factors, analysis of covariance was also performed. Results In univariate analyses the plasma insulin response after an oral glucose load, especially after 60min, was significantly related to blood pressure level. Plasma glucose was related to blood pressure level only at fasting. When adjusted for age, body mass index, plasma glucose response and alcohol consumption, plasma insulin concentrations after 30 and 60min in the highest quartile were significantly higher than those in the lowest quartile. Conclusions: Blood pressure was significantly and independently related to plasma insulin level after an oral glucose load in normotensive Japanese men with normal glucose tolerance. The results suggest that the relationship between blood pressure and insulin resistance already exists in a prehypertensive state even in a lean Asian population.
Nippon Eiseigaku Zasshi (japanese Journal of Hygiene) | 1994
Muneko Nishijo; Hideaki Nakagawa; Yuko Morikawa; Masaji Tabata; Masami Senma; Katsuyuki Miura; Ikiko Tsuritani; Ryumon Honda; Teruhiko Kido; Hidetoyo Teranishi; Shunichi Kawano
Nippon Eiseigaku Zasshi (japanese Journal of Hygiene) | 1990
Hideaki Nakagawa; Masaji Tabata; Yuko Morikawa; Yumiko Kitagawa; Masami Senma; Chieko Kanamori; Shunichi Kawano
Nippon Eiseigaku Zasshi (japanese Journal of Hygiene) | 1992
Yuko Morikawa; Hideaki Nakagawa; Masaji Tabata; Muneko Nishijo; Masami Senma; Yumiko Kitagawa; Shunichi Kawano; Hidetoyo Teranishi; Teruhiko Kido
Nippon Eiseigaku Zasshi (japanese Journal of Hygiene) | 1994
Katsushi Yoshita; Hideaki Nakagawa; Masaji Tabata; Yuko Morikawa; Muneko Nishijo; Masami Senma; Katsuyuki Miura; Masao Ishizaki; Teruhiko Kido; Shunichi Kawano
Japanese Journal of Health and Human Ecology | 1993
Zhao-Cheng Li; Yuko Morikawa; Hideaki Nakagawa; Masaji Tabata; Muneko Nishijo; Masami Senma; Yumiko Kitagawa; Shunichi Kawano; Teruhiko Kido; Yu-De Chen
Japanese Journal of Health and Human Ecology | 1992
Zhao-Cheng Li; Yuko Morikawa; Hideaki Nakagawa; Katsushi Yoshita; Masaji Tabata; Muneko Nishijo; Masami Senma; Shunichi Kawano; Teruhiko Kido; Yu-De Chen
Journal of The Japanese Association of Rural Medicine | 1990
Hideaki Nakagawa; Yuchi Naruse; Masaji Tabata; Yuko Morikawa; Masami Senma; Takako Kakiuchi; Hironari Kakiuchi; Sadanobu Kagamimori; Shunichi Kawano