Masao Kim

Surgical clinicopathologic study of malignant fibrous histiocytoma.

Fifteen men and six women, ranging in age from 20 to 79 years, with malignant fibrous histiocytoma comprised this series. Amputation of the right lower extremity was performed in one patient, wide resection in 7 and marginal excision in 9, respectively. In the other 4 patients, a non-curative resection was carried out. Adjuvant chemotherapy was prescribed post-operatively for 12 patients. Histologic grade of the surgical specimens was Stage I in 3, II in 6, III in 8 and IV in 4. Among fourteen patients living from 10 months to 9 years and 9 months after the operation, the 7 subjected to a wide resection are all disease free. Seven patients died of a local recurrence or a distant metastases. The survival rate of the patients with Stages I, II is significantly higher than those with Stages III, IV. These results show that a wide resection is to be favored and that staging is useful to estimate the prognosis.

PARENTERAL NUTRITION FOR CANCER PATIENTS

教室にて高カロリー輸液を施行した癌患者141名を基に臨床的検討を行った. この結果多くの症例において栄養維持改善が得られ, また種々の消化器症状を呈したものではその軽快・消失を見た.制癌剤との併用を行ったものでは高カロリー輸液は施行が副作用の出現をかなり防止しうる事が判明した. 殊に5FUの如く強い消化器副作用を呈する薬剤と併用した場合本輸液は極めて有用であり, 従来における癌治療の限界を大きく打破るものと期待できる.