Masao Wada

A removable functional group in a photochemical macrocyclic synthesis : Remote photocyclization with a pair system of phthalimide and 1,3-dithiolanyl groups

Abstract Based on a regioselective remote photocyclization of a pair system consisting of a phthalimide group and a dithiolanyl group, a variety of aza-cyclic compounds with methylene, ester, or amide groups in their frameworks were synthesized. The dithiolanyl group provides a removable donor, which effects a needed reaction followed by removal to give a new carbon skeleton leaving little trace of the precursor form.

Application of the remote photocyclization with a pair system of phthalimide and methylthio groups: A photochemical synthesis of macrolide models

Abstract Based on the regioselective remote photocyclization of a pair system consisting of a phthalimide group and a terminal sulfide group in their side chain, a variety of azathiacyclic compounds containing 9- to 27-membered rings were synthesized.

A synthetic approach to crown ether analogs by the remote photocyclization with a pai system of phthalimide and methylthio groups

Abstract Upon irradiation a homologous series of certain phthalimides ( 2a - c ) possessing a terminal sulfide function in their N-poly-ether side chain undergo regioselective remote photocyclization affording seven to fifteen-membered crown ether analogs ( 3a - c ) in moderate yields.