Masaya Kotsuka
Kansai Medical University
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Featured researches published by Masaya Kotsuka.
Nutrition and Cancer | 2016
Hiroaki Yanagimoto; Sohei Satoi; Tomohisa Yamamoto; Satoshi Hirooka; So Yamaki; Masaya Kotsuka; Hironori Ryota; Taku Michiura; Kentaro Inoue; Yoichi Matsui; Koji Tsuta; Masanori Kon
ABSTRACT The present study was conducted to determine whether active hexose correlated compound (AHCC), a functional food extracted from cultured basidiomycetes, possesses the potential to attenuate adverse events in unresectable pancreas ductal adenocarcinoma (PDAC) patients receiving chemotherapy. Unresectable PDAC patients receiving gemcitabine treatment (GEM) as the first-line chemotherapy were prospectively divided into 2 groups according to AHCC intake (AHCC group, n = 35) or not (control group, n = 40). The patients in the AHCC group ingested 6.0 g of AHCC for 2 mo. Hematological and nonhematological toxicity was compared between the AHCC and control groups. The C-reactive protein (CRP) elevation and albumin decline of the AHCC group were significantly suppressed as compared to the control group during the GEM administration (P = 0.0012, P = 0.0007). Patients in the AHCC group had less frequency of taste disorder caused by GEM (17% vs. 56%, P = 0.0007). Frequency of grade 3 in the modified Glasgow Prognostic Score (mGPS) during chemotherapy was found significantly less in the AHCC group (14%) than the control group (53%, P = 0.0005). AHCC intake can be effective in reducing the adverse events associated with chemotherapy and may contribute to maintaining the QOL of patients with PDAC during GEM administration.
Surgery | 2018
Yoichi Matsui; Satoshi Hirooka; Masaya Kotsuka; So Yamaki; Tomohisa Yamamoto; Hisashi Kosaka; Sohei Satoi
Background: Bile leakage after subtotal cholecystectomy (SC) is clinically serious. To prevent such leakage, we developed a new surgical technique in which a free piece of omentum is plugged into the gallbladder stump (omentum plugging technique). We evaluated whether the omentum plugging technique prevents bile leakage after subtotal cholecystectomy. Methods: Prospectively collected data of patients who had undergone subtotal cholecystectomy without cystic duct closure in the Department of Surgery of Kansai Medical University during the 12 years from January 2006 to March 2018 were reviewed retrospectively. The outcomes of patients who had undergone subtotal cholecystectomy with the omentum plugging technique (omentum plugging technique group) were compared with those of patients who had undergone subtotal cholecystectomy without the omentum plugging technique (Control group). The outcomes of interest were perioperative data and postoperative complications including bile leakage, necessity for interventions for complications, and duration of hospitalization. Results: Fifty of 2,447 consecutive patients (2.0%) had undergone subtotal cholecystectomy. Of these 50 patients, 18 were treated with the omentum plugging technique (omentum plugging technique group) and 32 were treated without the omentum plugging technique (Control group). One of 18 patients in the omentum plugging technique group and 14 of 32 in the Control group developed postoperative bile leakage. One postoperative interventional treatment for complications was performed in the omentum plugging technique group and 12 in the Control group. The duration of postoperative hospitalization was less in the omentum plugging technique group. Conclusion: The omentum plugging technique appears to be an effective operative technique for preventing postoperative bile leakage in selected situations when a “difficult gallbladder” is encountered.
Annals of Gastroenterological Surgery | 2018
Tomohisa Yamamoto; Sohei Satoi; Tsutomu Fujii; Suguru Yamada; Hiroaki Yanagimoto; So Yamaki; Hideki Takami; Satoshi Hirooka; Hisashi Kosaka; Masaya Kotsuka; Takayuki Miyara; Yasuhiro Kodera
The aim of this dual‐center randomized controlled trial was to determine the optimal duration of antimicrobial prophylaxis in patients treated with pancreaticoduodenectomy (PD) who underwent preoperative biliary drainage (PBD) but were without cholangitis.
International Journal of Surgery | 2017
Tomohisa Yamamoto; Sohei Satoi; Hiroaki Yanagimoto; Satoshi Hirooka; So Yamaki; Hironori Ryota; Masaya Kotsuka; Yoichi Matsui; Masanori Kon
Surgical Case Reports | 2016
Ilhan Karabicak; Sohei Satoi; Hiroaki Yanagimoto; Tomohisa Yamamoto; Satoshi Hirooka; So Yamaki; Hisashi Kosaka; Masaya Kotsuka; Kentoro Inoue; Yoichi Matsui; Masanori Kon
Pancreatology | 2017
Ilhan Karabicak; Sohei Satoi; Hiroaki Yanagimoto; Tomohisa Yamamoto; So Yamaki; Hisashi Kosaka; Satoshi Hirooka; Masaya Kotsuka; Taku Michiura; Kentaro Inoue; Yoichi Matsui; Masanori Kon
Cancer Chemotherapy and Pharmacology | 2016
Hiroaki Yanagimoto; Sohei Satoi; Masayuki Sho; Takahiro Akahori; Tomohisa Yamamoto; Satoshi Hirooka; So Yamaki; Masaya Kotsuka; Hironori Ryota; Shoichi Kinoshita; Satoshi Nishiwada; Minako Nagai; Naoya Ikeda; Koji Tsuta; Yoshiyuki Nakajima; Masanori Kon
Pancreatology | 2018
Hironori Ryota; Mitsuaki Ishida; Sohei Satoi; Hiroaki Yanagimoto; Yamamoto Tomohisa; Hisashi Kosaka; Satoshi Hirooka; So Yamaki; Masaya Kotsuka; Yoichi Matsui; Kazuichi Okazaki; Koji Tsuta
Pancreatology | 2018
So Yamaki; Sohei Satoi; Tomohisa Yamamoto; Hiroaki Yanagimoto; Hisashi Kosaka; Satoshi Hirooka; Masaya Kotsuka; Hironori Ryota; Yoichi Matsui
Pancreatology | 2018
Sohei Satoi; Yomohisa Yamamoto; Tsutomu Fujii; Suguru Yamada; Hiroaki Yanagimoto; So Yamaki; Hideki Takami; Satoshi Hirooka; Hisashi Kosaka; Masaya Kotsuka; Yasuhiro Kodera