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Dive into the research topics where Masayuki Ando is active.

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Featured researches published by Masayuki Ando.


Thorax | 1984

Surface morphology and function of human pulmonary alveolar macrophages from smokers and non-smokers.

Masayuki Ando; M Sugimoto; R Nishi; Moritaka Suga; S Horio; H Kohrogi; K Shimazu; S Araki

Pulmonary alveolar macrophages were obtained by saline lavage from 23 healthy male volunteers--10 non-smokers and 13 cigarette smokers. Lavage produced three times as many alveolar macrophages in smokers than in non-smokers. When macrophages from smokers and from non-smokers were incubated in vitro, more cells from smokers adhered to glass, spread out, and showed enhanced nitroblue tetrazolium (NBT) reduction. The surface morphology of alveolar macrophages from smokers showed more with a plate like appearance and ridge like membrane surface, while the macrophages from non-smokers were predominantly spherical with ruffles. The proportions of cells which stained highly for beta galactosidase were 55% in smokers and 11% in non-smokers. Thus, in a resting state in vitro, alveolar macrophages from smokers were more active than those from non-smokers. When, however, macrophages from smokers and non-smokers were incubated with immunobeads and with opsonised or non-opsonised BCG, the phagocytic activity and stimulated NBT reduction of alveolar macrophages from smokers were similar to or somewhat less than those of non-smokers.


Thorax | 1996

Hypersensitivity pneumonitis induced by a smut fungus Ustilago esculenta.

Kazuko Yoshida; Moritaka Suga; Hisato Yamasaki; Kenji Nakamura; Toyozo Sato; Makoto Kakishima; James A. Dosman; Masayuki Ando

A case of hypersensitivity pneumonitis caused by a smut fungus Ustilago esculenta is presented.


Clinical & Experimental Allergy | 1999

Effects of erythromycin on experimental extrinsic allergic alveolitis

Masafumi Miyajima; Moritaka Suga; Kazuko Nakagawa; K. Ito; Masayuki Ando

Recent clinical studies have demonstrated the efficacy of erythromycin for treating patients with chronic lower respiratory tract inflammation. Mechanisms related to the anti‐inflammatory action are yet to be determined.


Occupational and Environmental Medicine | 1995

Occupational hypersensitivity pneumonitis in Japan : data on a nationwide epidemiological study

Kazuko Yoshida; Moritaka Suga; Yuriko Nishiura; K Arima; R Yoneda; M Tamura; Masayuki Ando

OBJECTIVES--Diagnostic criteria were prepared for hypersensitivity pneumonitis (HP) and a nationwide survey was conducted to investigate epidemiological and clinical characteristics of HP in Japan. The results are presented with special focus on occupational HP and on the key to the diagnosis of HP. METHODS--A questionnaire was completed by 185 doctors from 185 hospitals (response rate 89.5%). All cases were verified according to diagnostic criteria; 835 cases were classified as HP (653 definite and 182 probable). These 835 cases (total HP) and 99 possible cases of HP diagnosed during the 1980s were analysed and presented as a case series study. RESULTS--Occupational HP was noted in 115 cases (13.8%). 21 occupations, and 20 aetiological antigens were listed. Farmers lung: 68 cases (59% of occupational HP) was the most prevalent diagnosis followed by 19 industrial workers who handled chemicals (for example, isocyanate) and 10 office workers. Unique cases of mushroom, greenhouse, and silkworm farmers, and a new type of bagassosis are also described. Adverse environmental conditions, immunological findings on examination, antigen challenge, and pathological findings were all significantly lower for possible than for total HP. This was not true for clinical findings. The differences in antibody analysis (6% positive of possible HP v 59% of total HP) and environmental challenge (3% v 74%) were notable. CONCLUSION--These data suggest that a careful interview about the environment and an antigen panel matched to variations in exposure are the key to the diagnosis.


Respirology | 1997

Summer-type hypersensitivity pneumonitis outside Japan: a case report and the state of the art.

Chul-Gyu Yoo; Young Whan Kim; Sung Koo Han; Kazuko Nakagawa; Moritaka Suga; Yuriko Nishiura; Masayuki Ando; Young-Soo Shim

Abstract A 61‐year‐old Korean housewife developed dyspnoea, cough and weight loss in the summer of 1994. The case was diagnosed as definite summer‐type hypersensitivity pneumonitis (SHP) according to the criteria proposed for hypersensitivity pneumonitis and for SHP. Her serum antibodies to Trichosporon were positive. Her symptoms were exacerbated after she returned home and Trichosporon was isolated from the patients home, indicating Trichosporon as the causative antigen. This is the first confirmed case of SHP outside Japan. On the basis of our research in SHP to date, we propose that SHP occurs in other Asian countries and that the assay of anti‐Trichosporon antibodies is useful for the diagnosis of the disease.


The American review of respiratory disease | 1984

Hypersensitivity pneumonitis induced by Trichosporon cutaneum

Kazuyoshi Shimazu; Masayuki Ando; Tetsunori Sakata; Kazuko Yoshida; Shukuro Araki


The Journal of Allergy and Clinical Immunology | 1990

Serotype-related antigen of Trichosporon cutaneum in the induction of summer-type hypersensitivity pneumonitis: Correlation between serotype of inhalation challenge-positive antigen and that of the isolates from patients' homes

Masayuki Ando; Tetsunori Sakata; Kazuko Yoshida; Hisato Yamasaki; Shukuro Araki; Kaoru Onoue; Takako Shinoda


Medical Mycology | 1997

Assignment and serotyping of Trichosporon species: The causative agents of summer-type hypersensitivity pneumonitis

Yuriko Nishiura; Kazuko Nakagawa-Yoshida; M. Suga; Takako Shinoda; E. Guého; Masayuki Ando


Sarcoidosis Vasculitis and Diffuse Lung Diseases | 1997

Mechanisms accounting for granulomatous responses in hypersensitivity pneumonitis

Moritaka Suga; Hisato Yamasaki; Kazuko Nakagawa; Hirotsugu Kohrogi; Masayuki Ando


The American review of respiratory disease | 1989

HLA-DQw3 in Japanese Summer-type Hypersensitivity Pneumonitis Induced by Trichosporon cutaneum

Masayuki Ando; Kenji Hirayama; Kyosei Soda; Ryoko Okubo; Shukuro Araki; Takehiko Sasazuki

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