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Dive into the research topics where Masutoshi Nojiri is active.

Publication


Featured researches published by Masutoshi Nojiri.


Journal of Applied Microbiology | 2013

Microbial asymmetric hydrolysis of 3-substituted glutaric acid diamides

Masutoshi Nojiri; Ken Uekita; Masatoshi Ohnuki; Naoaki Taoka; Yoshihiko Yasohara

Micro‐organisms were screened for their ability to produce (R)‐3‐(4‐chlorophenyl) glutaric acid monoamide (CGM) from 3‐(4‐chlorophenyl) glutaric acid diamide (CGD) through stereoselective hydrolysis. (R)‐CGM is a useful synthetic intermediate for arbaclofen.


Journal of Applied Microbiology | 2016

Improved efficiency of asymmetric hydrolysis of 3‐substituted glutaric acid diamides with an engineered amidase

Masutoshi Nojiri; Shinichi Yoshida; Hiroyuki Kanamaru; Yoshihiko Yasohara

To improve the efficiency of asymmetric hydrolysis of 3‐(4‐chlorophenyl) glutaric acid diamide (CGD) using a recombinant Comamonas sp. KNK3‐7 amidase (CoAM) produced in Escherichia coli.


Archive | 2008

Method for producing optically active 3-aminopiperidine or salt thereof

Kohei Mori; Masutoshi Nojiri; Akira Nishiyama; Naoaki Taoka


Journal of Molecular Catalysis B-enzymatic | 2014

Characterization of an enantioselective amidase from Cupriavidus sp. KNK-J915 (FERM BP-10739) useful for enzymatic resolution of racemic 3-piperidinecarboxamide

Masutoshi Nojiri; Naoaki Taoka; Yoshihiko Yasohara


Archive | 2015

Production method for optically active cyclic imino acid

Misato Matsui; 松井 美里; Masutoshi Nojiri; 野尻 増俊; Keita Yamashita; 山下 敬太; Yoshinori Hirai; 平井 義則; Akira Nishiyama; 西山 章; Shigeru Kawano; 川野 茂; Yoshihiko Yasohara


Applied Microbiology and Biotechnology | 2015

Imidase catalyzing desymmetric imide hydrolysis forming optically active 3-substituted glutaric acid monoamides for the synthesis of gamma-aminobutyric acid (GABA) analogs

Masutoshi Nojiri; Makoto Hibi; Hiroaki Shizawa; Nobuyuki Horinouchi; Yoshihiko Yasohara; Satomi Takahashi; Jun Ogawa


Tetrahedron-asymmetry | 2015

A practical chemoenzymatic synthesis of (R)-isovaline based on the asymmetric hydrolysis of 2-ethyl-2-methyl-malonamide

Masutoshi Nojiri; Fumi Yoshida; Yoshinori Hirai; Akira Nishiyama; Yoshihiko Yasohara


Archive | 2016

Vector, a transformant and a method to produce a polypeptide having activity to selectively hydrolyze a (R)-tropic acid amide in a racemic mixture

Masutoshi Nojiri; Hiroyuki Kanamaru; Akiko Nishi; Shigeru Kawano; Yoshihiko Yasohara


Archive | 2012

Enzyme function modification method and enzyme variant thereof

Shinichi Yoshida; Shunichi Taira; Masakatsu Nishihachijyo; Masutoshi Nojiri; Shigeru Kawano


Archive | 2012

Procédé de modification d'une fonction enzymatique et variant enzymatique résultant

Shinichi Yoshida; 吉田 慎一; Shunichi Taira; 俊一 平良; Masakatsu Nishihachijyo; 正克 西八條; Masutoshi Nojiri; 増俊 野尻; Shigeru Kawano; 川野 茂

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