Mathieu Guillot
Laval University
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Featured researches published by Mathieu Guillot.
Medical Physics | 2011
Mathieu Guillot; Luc Gingras; Louis Archambault; Sam Beddar; Luc Beaulieu
PURPOSE The purposes of this work were: (1) To determine if a spectral method can accurately correct the Cerenkov light effect in plastic scintillation detectors (PSDs) for situations where the Cerenkov light is dominant over the scintillation light and (2) to develop a procedural guideline for accurately determining the calibration factors of PSDs. METHODS The authors demonstrate, by using the equations of the spectral method, that the condition for accurately correcting the effect of Cerenkov light is that the ratio of the two calibration factors must be equal to the ratio of the Cerenkov light measured within the two different spectral regions used for analysis. Based on this proof, the authors propose two new procedures to determine the calibration factors of PSDs, which were designed to respect this condition. A PSD that consists of a cylindrical polystyrene scintillating fiber (1.6 mm3) coupled to a plastic optical fiber was calibrated by using these new procedures and the two reference procedures described in the literature. To validate the extracted calibration factors, relative dose profiles and output factors for a 6 MV photon beam from a medical linac were measured with the PSD and an ionization chamber. Emphasis was placed on situations where the Cerenkov light is dominant over the scintillation light and on situations dissimilar to the calibration conditions. RESULTS The authors found that the accuracy of the spectral method depends on the procedure used to determine the calibration factors of the PSD and on the attenuation properties of the optical fiber used. The results from the relative dose profile measurements showed that the spectral method can correct the Cerenkov light effect with an accuracy level of 1%. The results obtained also indicate that PSDs measure output factors that are lower than those measured with ionization chambers for square field sizes larger than 25 x 25 cm2, in general agreement with previously published Monte Carlo results. CONCLUSIONS The authors conclude that the spectral method can be used to accurately correct the Cerenkov light effect in PSDs. The authors confirmed the importance of maximizing the difference of Cerenkov light production between calibration measurements. The authors also found that the attenuation of the optical fiber, which is assumed to be constant in the original formulation of the spectral method, may cause a variation of the calibration factors in some experimental setups.
Medical Physics | 2008
Frédéric Lacroix; L. Archambault; Luc Gingras; Mathieu Guillot; A. Sam Beddar; Luc Beaulieu
A clinical prototype of a scintillating fiber dosimeter array for quality assurance applications is presented. The array consists of a linear array of 29 plastic scintillation detectors embedded in a water-equivalent plastic sheet coupled to optical fibers used to guide optical photons to a charge coupled device (CCD) camera. The CCD is packaged in a light-tight, radiation-shielded housing designed for convenient transport. A custom designed connector is used to ensure reproducible mechanical positioning of the optical fibers relative to the CCD. Profile and depth dose characterization measurements are presented and show that the prototype provides excellent dose measurement reproducibility (±0.8%) in-field and good accuracy (±1.6% maximum deviation) relative to the dose measured with an IC10 ionization chamber.
Medical Physics | 2011
Jean Gagnon; Dany Thériault; Mathieu Guillot; Louis Archambault; Sam Beddar; Luc Gingras; Luc Beaulieu
PURPOSE To compare the performance of plastic scintillation detectors (PSD) for quality assurance (QA) in stereotactic radiosurgery conditions to a microion-chamber (IC), Gafchromic EBT2 films, 60 008 shielded photon diode (SD) and unshielded diodes (UD), and assess a new 2D crosshair array prototype adapted to small field dosimetry. METHODS The PSD consists of a 1 mm diameter by 1 mm long scintillating fiber (BCF-60, Saint-Gobain, Inc.) coupled to a polymethyl-methacrylate optical fiber (Eska premier, Mitsubishi Rayon Co., Ltd., Tokyo, Japan). Output factors (S(c,p)) for apertures used in radiosurgery ranging from 4 to 40 mm in diameter have been measured. The PSD crosshair array (PSDCA) is a water equivalent device made up of 49 PSDs contained in a 1.63 cm radius area. Dose profiles measurements were taken for radiosurgery fields using the PSDCA and were compared to other dosimeters. Moreover, a typical stereotactic radiosurgery treatment using four noncoplanar arcs was delivered on a spherical phantom in which UD, IC, or PSD was placed. Using the Xknife planning system (Integra Radionics Burlington, MA), 15 Gy was prescribed at the isocenter, where each detector was positioned. RESULTS Output Factors measured by the PSD have a mean difference of 1.3% with Gafchromic EBT2 when normalized to a 10 × 10 cm(2) field, and 1.0% when compared with UD measurements normalized to the 35 mm diameter cone. Dose profiles taken with the PSD crosshair array agreed with other single detectors dose profiles in spite of the presence of the 49 PSDs. Gamma values comparing 1D dose profiles obtained with PSD crosshair array with Gafchromic EBT2 and UD measured profiles shows 98.3% and 100.0%, respectively, of detector passing the gamma acceptance criteria of 0.3 mm and 2%. The dose measured by the PSD for a complete stereotactic radiosurgery treatment is comparable to the planned dose corrected for its SD-based S(c,p) within 1.4% and 0.7% for 5 and 35 mm diameter cone, respectively. Furthermore, volume averaging of the IC can be observed for the 5 mm aperture where it differs by as much as 9.1% compared to the PSD measurement. The angular dependency of the UD is also observed, unveiled by an under-response around 2.5% of both 5 and 35 mm apertures. CONCLUSIONS Output Factors and dose profiles measurements performed, respectively, with the PSD and the PSDCA were in agreement with those obtained with the UD and EBT2 films. For stereotactic radiosurgery treatment verification, the PSD gives accurate results compared to the planning system and the IC once the latter is corrected to compensate for the averaging effect of the IC. The PSD provides precise results when used as a single detector or in a dense array, resulting in a great potential for stereotactic radiosurgery QA measurements.
Medical Physics | 2011
Mathieu Guillot; Luc Beaulieu; Louis Archambault; Sam Beddar; Luc Gingras
PURPOSE The objective of this work is to present a new 2D plastic scintillation detectors array (2D-PSDA) designed for the dosimetry of megavoltage (MV) energy photon beams in radiation therapy and to characterize its basic performance. METHODS We developed a 2D detector array consisting of 781 plastic scintillation detectors (PSDs) inserted into a plane of a water-equivalent phantom. The PSDs were distributed on a 26 × 26 cm(2) grid, with an interdetector spacing of 10 mm, except for two perpendicular lines centered on the detection plane, where the spacing was 5 mm. Each PSD was made of a 1 mm diameter by 3 mm long cylindrical polystyrene scintillating fiber coupled to a clear nonscintillating plastic optical fiber. All of the light signals emitted by the PSDs were read simultaneously with an optical system at a rate of one measurement per second. We characterized the performance of the optical system, the angular dependency of the device, and the perturbation of dose distributions caused by the hundreds of PSDs inserted into the phantom. We also evaluated the capacity of the system to monitor complex multileaf collimator (MLC) sequences such as those encountered in step-and-shoot intensity modulated radiation therapy (IMRT) plans. We compared our results with calculations performed by a treatment planning system and with measurements taken with a 2D ionization chamber array and with a radiochromic film. RESULTS The detector array that we developed allowed us to measure doses with an average precision of better than 1% for cumulated doses equal to or greater than 6.3 cGy. Our results showed that the dose distributions produced by the 6-MV photon beam are not perturbed (within ±1.1%) by the presence of the hundreds of PSDs located into the phantom. The results also showed that the variations in the beam incidences have little effect on the dose response of the device. For all incidences tested, the passing rates of the gamma tests between the 2D-PSDA and the treatment planning system were higher than 97.5% when the standard clinical tolerances of 3% or 3 mm were used. Excellent agreement was obtained between the doses measured and calculated when we used the 2D-PSDA for monitoring a MLC sequence from a step-and-shoot IMRT plan. CONCLUSIONS We demonstrated the feasibility of using a large number of PSDs in a new 2D-PSDA for the dosimetry of MV energy photon beams in radiation therapy. The excellent precision, accuracy, and low angular dependence of the device indicate that such a prototype could potentially be used as a high-accuracy quality assurance tool for IMRT and arc therapy patient plan verification. The homogeneity and water-equivalence of the prototype we built suggest that this technology could be extended to multiple detection planes by arranging the fibers into more complex orientations, opening the possibility for 3D dosimetry with PSDs.
Medical Physics | 2010
Frédéric Lacroix; Mathieu Guillot; M McEwen; C Cojocaru; Luc Gingras; A. Sam Beddar; Luc Beaulieu
PURPOSE This work presents the experimental extraction of the overall perturbation factor PQ in megavoltage electron beams for NACP-02 and Roos parallel-plate ionization chambers using a plastic scintillation detector (PSD). METHODS The authors used a single scanning PSD mounted on a high-precision scanning tank to measure depth-dose curves in 6, 12, and 18 MeV clinical electron beams. The authors also measured depth-dose curves using the NACP-02 and PTW Roos chambers. RESULTS The authors found that the perturbation factors for the NACP-02 and Roos chambers increased substantially with depth, especially for low-energy electron beams. The experimental results were in good agreement with the results of Monte Carlo simulations reported by other investigators. The authors also found that using an effective point of measurement (EPOM) placed inside the air cavity reduced the variation of perturbation factors with depth and that the optimal EPOM appears to be energy dependent. CONCLUSIONS A PSD can be used to experimentally extract perturbation factors for ionization chambers. The dosimetry protocol recommendations indicating that the point of measurement be placed on the inside face of the front window appear to be incorrect for parallel-plate chambers and result in errors in the R50 of approximately 0.4 mm at 6 MeV, 1.0 mm at 12 MeV, and 1.2 mm at 18 MeV.
Medical Physics | 2009
Frédéric Lacroix; A. Sam Beddar; Mathieu Guillot; Luc Beaulieu; Luc Gingras
PURPOSE The design of novel plastic scintillation detectors (PSDs) is impeded by the lack of a suitable framework to simulate and predict their performance. The authors propose to use the signal-to-noise ratio (SNR) to model the performance of PSDs that use charge-coupled devices (CCDs) as photodetectors. METHODS In PSDs using CCDs, the SNR is inversely related to the normalized standard deviation of the dose measurement. Thus, optimizing the SNR directly optimizes the systems precision. In this work, a model of SNR as a function of the system parameters is derived for optical fiber-based PSD systems. Furthermore, this proposed model is validated using experimental results. A formula for the efficiency of fiber coupling to CCDs is derived and used to simulate the performance of a PSD under varying magnifications. RESULTS The proposed model is shown to simulate the experimental performance of an actual PSD to a suitable degree of accuracy under various conditions. CONCLUSIONS The SNR constitutes a useful tool to simulate the dosimetric precision of PSDs. Using the SNR model, recommendations for the design and optimization of PSDs are provided. Using the same framework, recommendations for non-fiber-based PSDs are also provided.
Journal of Physics: Conference Series | 2010
Mathieu Guillot; Luc Gingras; Louis Archambault; S Beddar; Luc Beaulieu
In this work, we present a novel two Dimensional Plastic Scintillation Detector (2D-PSD) array designed to measure dose distributions generated by high energy photon beams from medical linear accelerators. This study aim to demonstrate that the dose distribution in the irradiated volume is not modified by the presence of several hundred plastic scintillation detectors (PSDs). The 2D-PSD consists of 781 PSDs inserted in a plastic water slab. The dose distributions measured with the 2D-PSD were compared to calculations from a treatment planning system (Pinnacle3, Philips Medical Systems) and with measurements taken with an ionization chambers array (MatriXX Evolution, IBA Dosimetry). Furthermore, a clinical head and neck IMRT plan was delivered on the 2D-PSD. A good agreement is obtained between the measured and planned dose distributions. The results show that the 2D arrangement presented in this work is water equivalent and transparent to x-ray radiation. As a consequence, our design could be extended to multiple detection planes, opening the possibility for 3D dosimetry with PSDs.
Medical Physics | 2011
Frédéric Lacroix; Mathieu Guillot; M McEwen; Luc Gingras; Luc Beaulieu
PURPOSE This work presents the experimental extraction of the perturbation factor in megavoltage electron beams for three models of silicon diodes (IBA Dosimetry, EFD and SFD, and the PTW 60012 unshielded) using a plastic scintillation detector (PSD). METHODS The authors used a single scanning PSD mounted on a high-precision scanning tank to measure depth-dose curves in 6-, 12-, and 18-MeV clinical electron beams. They also measured depth-dose curves using the IBA Dosimetry, EFD and SFD, and the PTW 60012 unshielded diodes. The authors used the depth-dose curves measured with the PSD as a perturbation-free reference to extract the perturbation factors of the diodes. RESULTS The authors found that the perturbation factors for the diodes increased substantially with depth, especially for low-energy electron beams. The experimental results show the same trend as published Monte Carlo simulation results for the EFD diode; however, the perturbations measured experimentally were greater. They found that using an effective point of measurement (EPOM) placed slightly away from the source reduced the variation of perturbation factors with depth and that the optimal EPOM appears to be energy dependent. CONCLUSIONS The manufacturer recommended EPOM appears to be incorrect at low electron energy (6 MeV). In addition, the perturbation factors for diodes may be greater than predicted by Monte Carlo simulations.
Medical Physics | 2010
Jean Gagnon; Dany Thériault; Mathieu Guillot; Louis Archambault; S Beddar; Luc Gingras; Luc Beaulieu
Purpose: To compare the performance of a plastic scintillation detector(PSD) for quality assurance (QA) in stereotactic radiosurgery to micro‐chamber, gafchromic films, shielded and unshielded diodes. Method and Materials: The PSD consists of a 1 mm diameter by 1 mm long scintillating fiber (BCF‐60, Saint‐Gobain Inc.) coupled to a polymethyl‐methacrylate optical fiber (Eska premier, Mitsubitshi). Output factors and dose profiles for apertures used in radiosurgery ranging from 4 mm to 40 mm in diameter have been measured with the PSD, a micro‐chamber (MC) (A16, Exradin), a shielded diode (SD) (type 60008, PTW), an unshielded diode (UD) (SFD stereotactic, IBA Dosimetry) and gafchromic EBT films. Moreover, a typical stereotactic radiosurgery treatment using 4 non‐coplanar arcs was delivered on a spherical phantom in which UD, MC or PSD was placed. Using the Xknife planning system (Radionics), 15 Gy was prescribed at the isocenter, where each detector was positioned. Results: The output factors measured with the PSD are within a maximum discrepancy of 3.5% compared to UD for the small apertures when normalized to the 35 mm cone. For larger cones the PSD is within 1.3% compared to the SD and the MC. When done with a 35 mm cone, the measured dose for an entire typical stereotactic plan by the PSD is within 1.8% of the measurement performed using the MC and within 1% of the planning system. Volume averaging of the MC can be observed for the 5 mm aperture, where the PSD measurement differs by as much as 9.1%. Conclusion: For stereotactic radiosurgery treatment verification, the PSD gives accurate results compared to the MC once the output factor ratio of both dosimeters are taken into account to correct for the averaging effect of the MC. The PSD shows great potential for stereotactic radiosurgery QA measurements.
Medical Physics | 2010
Frédéric Lacroix; Mathieu Guillot; M McEwen; C Cojocaru; Luc Gingras; S Beddar; Luc Beaulieu
Purpose: To present a method to experimentally extract the overall perturbation factor p Q (the product of p wall and p repl ) in megavoltage electron beams for NACP and Roos parallel plate chambers using a perturbation‐free plastic scintillation detector(PSD).Method and Materials: We used a single scanning PSD mounted on a high precision scanning stage to measure depth dose curves in 6 12 and 18 MeV clinical electron beams. We also measured depth doses using NACP and Roos parallel plate chambers. Perturbation factors were extracted by comparing PDDs measured using the Roos and NACP chamber to PDDs measured using the PSD. Monte‐Carlo simulations using EGSnrc were performed to validate that the PSD is a perturbation‐free detector in electron beams.Results: Our experimental results show excellent concordance with the Monte‐Carlo simulation results of various authors on the subject. We show that the perturbation factors for the NACP and Roos chambers increase substantially with depth especially for low energy electron beams. We show that using an effective point of measurement (EPOM) placed inside the air cavity reduces the variation of perturbation factors with depth. The protocol recommendations suggesting to place the point of measurement at the inside face of the front window appear to be incorrect for parallel plate chambers and lead to errors in the R50 of approximately 0.4 mm at 6 MeV 1 mm at 12 MeV and 1.2 mm at 18 MeV. Conclusion: The results indicate that PSDs can be used as perturbation‐free detectors in reference dosimetry and that PSDs can be used to experimentally extract ionization chamberperturbation factors.